ID   A0A0H5MIF9_YERIN        Unreviewed;       511 AA.
AC   A0A0H5MIF9;
DT   14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2015, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   RecName: Full=Protein CyaE {ECO:0000256|PIRNR:PIRNR001892};
GN   Name=ttgC {ECO:0000313|EMBL:CRY56891.1};
GN   ORFNames=ERS008476_03938 {ECO:0000313|EMBL:CRY56891.1};
OS   Yersinia intermedia.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=631 {ECO:0000313|EMBL:CRY56891.1, ECO:0000313|Proteomes:UP000043316};
RN   [1] {ECO:0000313|Proteomes:UP000043316}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=R148 {ECO:0000313|Proteomes:UP000043316};
RG   Pathogen Informatics;
RL   Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: CyaE is necessary for transport of calmodulin-sensitive
CC       adenylate cyclase-hemolysin (cyclolysin).
CC       {ECO:0000256|PIRNR:PIRNR001892}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane
CC       {ECO:0000256|PIRNR:PIRNR001892}; Peripheral membrane protein
CC       {ECO:0000256|PIRNR:PIRNR001892}.
CC   -!- SIMILARITY: Belongs to the outer membrane factor (OMF) (TC 1.B.17)
CC       family. {ECO:0000256|ARBA:ARBA00007613, ECO:0000256|PIRNR:PIRNR001892}.
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DR   EMBL; CWJI01000018; CRY56891.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0H5MIF9; -.
DR   Proteomes; UP000043316; Unassembled WGS sequence.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015562; F:efflux transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1600.10; Outer membrane efflux proteins (OEP); 1.
DR   InterPro; IPR028351; CyaE.
DR   InterPro; IPR003423; OMP_efflux.
DR   PANTHER; PTHR30203; OUTER MEMBRANE CATION EFFLUX PROTEIN; 1.
DR   PANTHER; PTHR30203:SF29; PROTEIN CYAE; 1.
DR   Pfam; PF02321; OEP; 2.
DR   PIRSF; PIRSF001892; CyaE; 1.
DR   SUPFAM; SSF56954; Outer membrane efflux proteins (OEP); 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane {ECO:0000256|PIRNR:PIRNR001892};
KW   Cytolysis {ECO:0000256|PIRNR:PIRNR001892};
KW   Hemolysis {ECO:0000256|PIRNR:PIRNR001892};
KW   Membrane {ECO:0000256|PIRNR:PIRNR001892}; Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022452};
KW   Transmembrane beta strand {ECO:0000256|ARBA:ARBA00022452};
KW   Transport {ECO:0000256|PIRNR:PIRNR001892}.
FT   SIGNAL          1..29
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           30..511
FT                   /note="Protein CyaE"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5005221642"
SQ   SEQUENCE   511 AA;  53860 MW;  9F747973D52523E0 CRC64;
     MTHAILKARI AKISLTFSVL GLSMLIAGCA TDRLDLAPAS YAEPWAPNAN TGASMVGGNF
     SVPANPLVAE LAQPLSIKSE HRYSLPELID IAQNQNPDTR IAWQQARQAA LAVGMGEAIF
     LPIISASVIG GYQSTTTPLP YAIGNEKDLK TSGSAVVPAL ALQWLIFDFG QRSALLDAAK
     HISYASNVTF NGMHQKVIYD VTRTYFQYGA AQNQQKIAEE TLKNSLKIQD AAEERRKNGI
     ATTVEVALAR QQVAQSELRR VMTKGTERDA YQALLSAMGV SPTLAINVAY AEDRALPDVA
     SPPTEKMIRL ALSQRPDVLA SYAAAEAAKA GIKAAEADFL PKVYLAGAVA GGDGRFDIQG
     LPGISPQTSS SSILLGVSVP LYDGGIRAAR VKEAESRAAV AAEGFKKTQE LAVREIVVAA
     DTLRSALESN QAALNLVKTS FITYDAALES YRNGVGTITV ANEAANGLLN AQQMSTDAHA
     ASLVAAANLA FVMGKMTNSA DLPGTLTASV P
//