ID A0A0H5S5F9_BRUMA Unreviewed; 436 AA.
AC A0A0H5S5F9;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=XK-related protein {ECO:0000256|RuleBase:RU910716};
GN Name=bma-ced-8 {ECO:0000313|WormBase:Bm3197};
GN Synonyms=Bma-ced-8 {ECO:0000313|EMBL:CRZ23854.1,
GN ECO:0000313|WBParaSite:Bm3197.1};
GN ORFNames=Bm3197 {ECO:0000313|WormBase:Bm3197}, BM_Bm3197
GN {ECO:0000313|EMBL:CRZ23854.1};
OS Brugia malayi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX NCBI_TaxID=6279 {ECO:0000313|EMBL:CRZ23854.1};
RN [1] {ECO:0000313|EMBL:CRZ23854.1, ECO:0000313|Proteomes:UP000006672}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CRZ23854.1,
RC ECO:0000313|Proteomes:UP000006672};
RX PubMed=17885136; DOI=10.1126/science.1145406;
RA Ghedin E., Wang S., Spiro D., Caler E., Zhao Q., Crabtree J., Allen J.E.,
RA Delcher A.L., Guiliano D.B., Miranda-Saavedra D., Angiuoli S.V., Creasy T.,
RA Amedeo P., Haas B., El-Sayed N.M., Wortman J.R., Feldblyum T., Tallon L.,
RA Schatz M., Shumway M., Koo H., Salzberg S.L., Schobel S., Pertea M.,
RA Pop M., White O., Barton G.J., Carlow C.K., Crawford M.J., Daub J.,
RA Dimmic M.W., Estes C.F., Foster J.M., Ganatra M., Gregory W.F.,
RA Johnson N.M., Jin J., Komuniecki R., Korf I., Kumar S., Laney S., Li B.W.,
RA Li W., Lindblom T.H., Lustigman S., Ma D., Maina C.V., Martin D.M.,
RA McCarter J.P., McReynolds L., Mitreva M., Nutman T.B., Parkinson J.,
RA Peregrin-Alvarez J.M., Poole C., Ren Q., Saunders L., Sluder A.E.,
RA Smith K., Stanke M., Unnasch T.R., Ware J., Wei A.D., Weil G.,
RA Williams D.J., Zhang Y., Williams S.A., Fraser-Liggett C., Slatko B.,
RA Blaxter M.L., Scott A.L.;
RT "Draft genome of the filarial nematode parasite Brugia malayi.";
RL Science 317:1756-1760(2007).
RN [2] {ECO:0000313|EMBL:CRZ23854.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CRZ23854.1};
RA Gao Y.W., Fan S.T., Sun H.T., Wang Z., Gao X.L., Li Y.G., Wang T.C.,
RA Zhang K., Xu W.W., Yu Z.J., Xia X.Z.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|WBParaSite:Bm3197.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (DEC-2019) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU910716}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU910716}.
CC -!- SIMILARITY: Belongs to the XK family. {ECO:0000256|ARBA:ARBA00008789,
CC ECO:0000256|RuleBase:RU910716}.
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DR EMBL; LN856931; CRZ23854.1; -; Genomic_DNA.
DR STRING; 6279.A0A0H5S5F9; -.
DR EnsemblMetazoa; Bm3197.1; Bm3197.1; WBGene00223458.
DR WBParaSite; Bm3197.1; Bm3197.1; WBGene00223458.
DR WormBase; Bm3197; BM26645; WBGene00223458; Bma-ced-8.
DR OMA; SWIARCT; -.
DR OrthoDB; 2879793at2759; -.
DR Proteomes; UP000006672; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR018629; XK-rel.
DR PANTHER; PTHR16024:SF6; CELL DEATH ABNORMALITY PROTEIN 8; 1.
DR PANTHER; PTHR16024; XK-RELATED PROTEIN; 1.
DR Pfam; PF09815; XK-related; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU910716};
KW Reference proteome {ECO:0000313|Proteomes:UP000006672};
KW Transmembrane {ECO:0000256|RuleBase:RU910716};
KW Transmembrane helix {ECO:0000256|RuleBase:RU910716}.
FT TRANSMEM 88..110
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 130..155
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 188..208
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 220..239
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 287..307
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 319..339
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 345..366
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 378..398
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
SQ SEQUENCE 436 AA; 50555 MW; 1AD0CAA3F84E5391 CRC64;
MREIGNEGPL RNESNGTAYF WKYPVKRNIR FEDDAFKDCT DRLPHTLTVR NFDIFCFIFS
AASYLADIGS DATVAYIHYC EHRMWASIFI SILTVLPSLI LNIVSFIWWI DDVSAHAVQQ
GMKHAYSKQF TLRIIMCLLQ ISPLVWYVEA ILAAIKFRMT KKRNEKLSSY IAMIQAERDA
ALLRFFEAFL ESVPQMLVQG IALTHAFYSL NPSNNFPKWM LTQVVSISFS LLSSCWSFVI
QHRSLRLSRP DKENITPSGA LMQLLWRIFT VSSRYICFVL FILNYQYWIL ALFIIHFIIS
VTHVSVLQPF ETKFKNKSVK VGLIVICAAV HFFAPYNMAE GRSRYRYTVA YCIEAIEIVI
LSKMAMSNER YTLPYKEYVE IGIYVLFLVG IFFMLLYYGC FHPNIVHCHR TGGVSSSCIR
TCQIVLYPSN RVMEES
//
