ID A0A0H5S9F0_BRUMA Unreviewed; 795 AA.
AC A0A0H5S9F0;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 08-NOV-2023, entry version 31.
DE SubName: Full=BMA-SET-11, isoform a {ECO:0000313|EMBL:CRZ25009.1};
GN Name=Bma-set-11 {ECO:0000313|EMBL:CRZ25009.1};
GN ORFNames=Bm10440 {ECO:0000313|WormBase:Bm10440a}, BM_Bm10440
GN {ECO:0000313|EMBL:CRZ25009.1};
OS Brugia malayi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX NCBI_TaxID=6279 {ECO:0000313|EMBL:CRZ25009.1};
RN [1] {ECO:0000313|EMBL:CRZ25009.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CRZ25009.1};
RX PubMed=17885136; DOI=10.1126/science.1145406;
RA Ghedin E., Wang S., Spiro D., Caler E., Zhao Q., Crabtree J., Allen J.E.,
RA Delcher A.L., Guiliano D.B., Miranda-Saavedra D., Angiuoli S.V., Creasy T.,
RA Amedeo P., Haas B., El-Sayed N.M., Wortman J.R., Feldblyum T., Tallon L.,
RA Schatz M., Shumway M., Koo H., Salzberg S.L., Schobel S., Pertea M.,
RA Pop M., White O., Barton G.J., Carlow C.K., Crawford M.J., Daub J.,
RA Dimmic M.W., Estes C.F., Foster J.M., Ganatra M., Gregory W.F.,
RA Johnson N.M., Jin J., Komuniecki R., Korf I., Kumar S., Laney S., Li B.W.,
RA Li W., Lindblom T.H., Lustigman S., Ma D., Maina C.V., Martin D.M.,
RA McCarter J.P., McReynolds L., Mitreva M., Nutman T.B., Parkinson J.,
RA Peregrin-Alvarez J.M., Poole C., Ren Q., Saunders L., Sluder A.E.,
RA Smith K., Stanke M., Unnasch T.R., Ware J., Wei A.D., Weil G.,
RA Williams D.J., Zhang Y., Williams S.A., Fraser-Liggett C., Slatko B.,
RA Blaxter M.L., Scott A.L.;
RT "Draft genome of the filarial nematode parasite Brugia malayi.";
RL Science 317:1756-1760(2007).
RN [2] {ECO:0000313|EMBL:CRZ25009.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CRZ25009.1};
RA Gao Y.W., Fan S.T., Sun H.T., Wang Z., Gao X.L., Li Y.G., Wang T.C.,
RA Zhang K., Xu W.W., Yu Z.J., Xia X.Z.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LN856992; CRZ25009.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0H5S9F0; -.
DR WormBase; Bm10440a; BM40505; WBGene00230701; -.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0140938; F:histone H3 methyltransferase activity; IEA:UniProt.
DR GO; GO:0002039; F:p53 binding; IEA:InterPro.
DR GO; GO:0016279; F:protein-lysine N-methyltransferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR043550; EHMT1/EHMT2.
DR InterPro; IPR007728; Pre-SET_dom.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR PANTHER; PTHR46307; G9A, ISOFORM B; 1.
DR PANTHER; PTHR46307:SF4; G9A, ISOFORM B; 1.
DR Pfam; PF00856; SET; 1.
DR SMART; SM00317; SET; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF82199; SET domain; 1.
DR PROSITE; PS50867; PRE_SET; 1.
DR PROSITE; PS50280; SET; 1.
PE 4: Predicted;
KW Chromosome {ECO:0000256|ARBA:ARBA00022454}.
FT DOMAIN 515..578
FT /note="Pre-SET"
FT /evidence="ECO:0000259|PROSITE:PS50867"
FT DOMAIN 581..697
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
FT REGION 742..765
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 795 AA; 91969 MW; 89BDE9F6CA151EC5 CRC64;
MEEEKTNCKF DPCTAGSSEN KYPCECYCFR LSRNETPLEQ NVHCLCTGEN RRYGIKYRCR
RKALTFLSNI IDGKTVEQSF CSIHSEMVHQ HRLCLVCYAF CTEGELKVCN ELGVQHWMHA
DCYHSWKEAC CHCNILYSAS SHFTLFPYKD PLFEKLETVF PKMTRGLQLN VLALCEKENY
SWLISELDTF QSVRSNSLST ERPFYMKSQL LLRELWETFR ADKSPYEHRK YYLDSIKFAI
QCCDRLSLLI ILQFLDVTVD GECLLFAVEA NDAFSVRVLL HHGAPISFQK KSGEKIDSLS
VAFILGNCAS AEEILKFLNY RSTRMQEFMR NRLLEFINHH DYRVVDLLLA YGANIYDRSE
KGKSVFHRMT QNNDQQLAIA TATKLFEKTV IVPSFIDAED YRHRTALQLA CARCHWKLAE
FFLQRGAAPK GLWTDMRLPE FLRSYIDRVG RELKLRKFLS VSRKYITHDI TMGRERVAIP
LENGTDDGAT LDPNFEYVNA VDDHDSFQTH IDFSLACRCA NDCQVDCPCL ARCTYDADGH
LTGRAVELAD KAELGVLLEC SSCCFCSNKC RSRVAQKGVH CGLEVYRTRK YGWAVRTCSL
IMKGSFVCEY TGELISDADA DKREDDTYLF EIVDETSAYC IDAKFKGNVS RFINHSCEAN
LVTLRVVWDA NIRHLPHICF YAKRDIQQGE ELTIDYGNQW WDVKLRNFPC QCGSKSCKYT
STVREELLRD GLITAEENRE LEEPFGGPEG YRHSTNHKTS GPQIKRSCHE RDRGIYKYRN
PWSVCEQTYN PLIFF
//
