ID A0A0H5SBD7_BRUMA Unreviewed; 1472 AA.
AC A0A0H5SBD7;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 13-SEP-2023, entry version 42.
DE SubName: Full=BMA-DENN-4 {ECO:0000313|EMBL:CRZ25852.1, ECO:0000313|WBParaSite:Bm4253a.1};
GN Name=Bma-denn-4 {ECO:0000313|EMBL:CRZ25852.1,
GN ECO:0000313|WBParaSite:Bm4253a.1};
GN ORFNames=BM_Bm4253 {ECO:0000313|EMBL:CRZ25852.1};
OS Brugia malayi (Filarial nematode worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Brugia.
OX NCBI_TaxID=6279 {ECO:0000313|EMBL:CRZ25852.1};
RN [1] {ECO:0000313|EMBL:CRZ25852.1, ECO:0000313|Proteomes:UP000006672}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CRZ25852.1,
RC ECO:0000313|Proteomes:UP000006672};
RX PubMed=17885136; DOI=10.1126/science.1145406;
RA Ghedin E., Wang S., Spiro D., Caler E., Zhao Q., Crabtree J., Allen J.E.,
RA Delcher A.L., Guiliano D.B., Miranda-Saavedra D., Angiuoli S.V., Creasy T.,
RA Amedeo P., Haas B., El-Sayed N.M., Wortman J.R., Feldblyum T., Tallon L.,
RA Schatz M., Shumway M., Koo H., Salzberg S.L., Schobel S., Pertea M.,
RA Pop M., White O., Barton G.J., Carlow C.K., Crawford M.J., Daub J.,
RA Dimmic M.W., Estes C.F., Foster J.M., Ganatra M., Gregory W.F.,
RA Johnson N.M., Jin J., Komuniecki R., Korf I., Kumar S., Laney S., Li B.W.,
RA Li W., Lindblom T.H., Lustigman S., Ma D., Maina C.V., Martin D.M.,
RA McCarter J.P., McReynolds L., Mitreva M., Nutman T.B., Parkinson J.,
RA Peregrin-Alvarez J.M., Poole C., Ren Q., Saunders L., Sluder A.E.,
RA Smith K., Stanke M., Unnasch T.R., Ware J., Wei A.D., Weil G.,
RA Williams D.J., Zhang Y., Williams S.A., Fraser-Liggett C., Slatko B.,
RA Blaxter M.L., Scott A.L.;
RT "Draft genome of the filarial nematode parasite Brugia malayi.";
RL Science 317:1756-1760(2007).
RN [2] {ECO:0000313|EMBL:CRZ25852.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=FR3 {ECO:0000313|EMBL:CRZ25852.1};
RA Gao Y.W., Fan S.T., Sun H.T., Wang Z., Gao X.L., Li Y.G., Wang T.C.,
RA Zhang K., Xu W.W., Yu Z.J., Xia X.Z.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|WBParaSite:Bm4253a.1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (DEC-2020) to UniProtKB.
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DR EMBL; LN857014; CRZ25852.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0H5SBD7; -.
DR STRING; 6279.A0A0H5SBD7; -.
DR EnsemblMetazoa; Bm4253a.1; Bm4253a.1; WBGene00224514.
DR WBParaSite; Bm4253a.1; Bm4253a.1; WBGene00224514.
DR InParanoid; A0A0H5SBD7; -.
DR OMA; NAFFDDC; -.
DR OrthoDB; 1079051at2759; -.
DR Proteomes; UP000006672; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR Gene3D; 2.100.10.50; -; 1.
DR Gene3D; 3.40.50.11500; -; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR001194; cDENN_dom.
DR InterPro; IPR005112; dDENN_dom.
DR InterPro; IPR043153; DENN_C.
DR InterPro; IPR023341; MABP.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR037516; Tripartite_DENN.
DR InterPro; IPR005113; uDENN_dom.
DR PANTHER; PTHR12296; DENN DOMAIN-CONTAINING PROTEIN 4; 1.
DR PANTHER; PTHR12296:SF30; DENN DOMAIN-CONTAINING PROTEIN CRAG; 1.
DR Pfam; PF03455; dDENN; 1.
DR Pfam; PF02141; DENN; 1.
DR Pfam; PF03456; uDENN; 1.
DR SMART; SM00801; dDENN; 1.
DR SMART; SM00799; DENN; 1.
DR SMART; SM00800; uDENN; 1.
DR PROSITE; PS50211; DENN; 1.
DR PROSITE; PS51498; MABP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006672}.
FT DOMAIN 38..195
FT /note="MABP"
FT /evidence="ECO:0000259|PROSITE:PS51498"
FT DOMAIN 187..645
FT /note="UDENN"
FT /evidence="ECO:0000259|PROSITE:PS50211"
FT REGION 1110..1133
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1472 AA; 165632 MW; 626AA05416F52B47 CRC64;
MGECRRLFEY FVIVGLEDGA EDLVPTAQEC GCRNSAPLAP ITDICVIFPG LGETVPDGFE
RITSTPMGYA ADLNHGSLRT PSVFLCFRRG YHKPPLVDIG VLDEGRGEKP MLDSNTVLTT
PFGRSANVNN ASPGVFLTYR RAQANSAPSQ LVVTHICVIL ANKGETAPHT YYKIPKNLNK
GMVGSDVFLC YKKSQGASKR IAYKPAVLDH FPLDNKFTLA QNIPMFCLPV GALIECWPAR
CQPPDKSFST FVLTDQDGSK LYGSSVTFYE PYTKPLSMEQ MEKLELVNET VTRGTVEDSS
NTNDPAEQMT FHSNMSICII SKYPFFNAFK RFLFYLHRIS LSGAHSVPVE RYISHLLYEV
SFPSPRCPRV LVQLGNETIS FESHDDSQLP LSGAAFFDTL KCLGPQNLMY LMLLALLEQK
ILVHSLRPWL LTAVAESVCA LMFPFHWQCP YIPQCPLSLA GVLHAPLPFI AGVDSRYFDL
YEDPPSDVTC FDLDTSTISF SSVRQTLKLS MLPKKASRQL KNTLEKLHRR LYQEEFNVIA
LRKNMDFMPL DIDYDIQRKK RMLEISVQDA FLRFMASLMQ GYTAYLRPIR CAPRCVGATD
TGSLFDLDAF LHSRDRSSLE FFKRFSETQS FNRFIEERSF VSDKNTYNAF FDECIAKISQ
NDNRSSNDSL VEYEMSASCQ TEFVPPPEST LNSDGQELTY KYEYFPRTLE PALFQLENLH
KMSIEMKGSD YLESALIRTK QEARSALETA ILNARHSPVT WPKTLLFYAY SIWFMLLPSL
VHLAKSKVKI LRLALHVLDR MEYSGILPLD QVCYRIVIQL CGDFGYPILA VKVLQAMQRS
GMEQNAVTYG IYHQAVLKGG WPVGDRVEAV KAWNRLAIVV RAISLFKMNL SLASSRHSLQ
FGSISAADSW SHSENASYGS ATKENEPVSV EVPTATALNM NEDESALNQS SQLRNTVAAF
SEGNNSSDLL VDPLGAINMT QNLSTTASRQ AGETMSPSRL RFIKEHSTSP FANELLHNEL
VDSRLNEKSN SWLRGLTSSP IVSKLMRSNT ASNFDSPFDK NDSSLTLSPS LASLVNQMKK
GYDDVLQAGS LSSRLREGVN TLVNEVRSLN RSYTKDGGES THSSQREVNE QSDQQLHLND
PLFQLDSGSH CSLLPSDWWL ADQIFASAST PHELIDVAIS SASLCPACKM VVYDEDLMSG
WTVDESNLNT SCVYCECAFV PSLTVKIHPR EMPVEGSWYL LSSFATKTSD DDNTPRYNGD
NESIASQLSV PFLSPLVLRR ELENLLSGNY LLPVYSSLRH SNPIVFWNVL YYSRRLSLPT
HFPSWLGQSV HVRCVYDVPV LHTEFTPLFF VNPSHKDGLL PSSERSVSIW RHVITAVQQS
SILRALQVIL SENRNATDNG KFPRRFPLFR DVQFVALDKY GSAVDRDQLD EQYRSDFERL
PPRILPLLPY SDYPPKSLSR ICRKIFLPLD VF
//
