ID A0A0J0XHU7_9TREE Unreviewed; 1195 AA.
AC A0A0J0XHU7;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 22-FEB-2023, entry version 34.
DE RecName: Full=DNA mismatch repair protein {ECO:0000256|PIRNR:PIRNR037677};
GN ORFNames=CC85DRAFT_287262 {ECO:0000313|EMBL:KLT40648.1};
OS Cutaneotrichosporon oleaginosum.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Trichosporonales; Trichosporonaceae; Cutaneotrichosporon.
OX NCBI_TaxID=879819 {ECO:0000313|EMBL:KLT40648.1, ECO:0000313|Proteomes:UP000053611};
RN [1] {ECO:0000313|EMBL:KLT40648.1, ECO:0000313|Proteomes:UP000053611}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IBC0246 {ECO:0000313|EMBL:KLT40648.1,
RC ECO:0000313|Proteomes:UP000053611};
RG DOE Joint Genome Institute;
RA Kourist R., Kracht O., Bracharz F., Lipzen A., Nolan M., Ohm R.,
RA Grigoriev I., Sun S., Heitman J., Bruck T., Nowrousian M.;
RT "Genomics and transcriptomics of the oil-accumulating basidiomycete yeast
RT T. oleaginosus allow insights into substrate utilization and the diverse
RT evolutionary trajectories of mating systems in fungi.";
RL Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the post-replicative DNA mismatch repair system
CC (MMR). {ECO:0000256|PIRNR:PIRNR037677, ECO:0000256|RuleBase:RU003756}.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC {ECO:0000256|PIRNR:PIRNR037677, ECO:0000256|RuleBase:RU003756}.
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DR EMBL; KQ087231; KLT40648.1; -; Genomic_DNA.
DR RefSeq; XP_018277139.1; XM_018423792.1.
DR AlphaFoldDB; A0A0J0XHU7; -.
DR STRING; 879819.A0A0J0XHU7; -.
DR GeneID; 28984395; -.
DR OrthoDB; 168255at2759; -.
DR Proteomes; UP000053611; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR Gene3D; 1.10.1420.10; -; 2.
DR Gene3D; 3.40.1170.10; DNA repair protein MutS, domain I; 1.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR007695; DNA_mismatch_repair_MutS-lik_N.
DR InterPro; IPR017261; DNA_mismatch_repair_MutS/MSH.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR016151; DNA_mismatch_repair_MutS_N.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11361:SF148; DNA MISMATCH REPAIR PROTEIN MSH6; 1.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR Pfam; PF01624; MutS_I; 1.
DR Pfam; PF05188; MutS_II; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF05190; MutS_IV; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF037677; DNA_mis_repair_Msh6; 1.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF55271; DNA repair protein MutS, domain I; 1.
DR SUPFAM; SSF53150; DNA repair protein MutS, domain II; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PIRNR:PIRNR037677};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763, ECO:0000256|PIRNR:PIRNR037677};
KW DNA repair {ECO:0000256|PIRNR:PIRNR037677, ECO:0000256|RuleBase:RU003756};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PIRNR:PIRNR037677};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|PIRNR:PIRNR037677};
KW Reference proteome {ECO:0000313|Proteomes:UP000053611}.
FT DOMAIN 1026..1042
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
FT REGION 1..160
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 183..245
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 767..794
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 20..57
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 84..98
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 105..158
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 186..202
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 214..245
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1195 AA; 131473 MW; 45BD8DFD73170E8C CRC64;
MPSTKQTTLA SFFGVPKKGP APKPSTPALS KPSCAPPPTS SPPSSSLHTP PSDPIDSPSL
PKRAKRASIV VAVNDDHLTP PPVMSPKKRA PALAPATPSP EPVTDDAMDV DHQDSPLVSR
RRAKRKVVYV ESDASSDEDV SKANGRKPRK SLKADDSEDE FVFDADDDAA LAAAADEYDA
MISDAPSPSI ASTYSRSASP VKQPARKKTA VSKSASKKAT TSGGSTPASA SRAPPLVSRT
SSSGGGSSLF LTAAERKKLQ AKEDKREAET CFSFLNDIKD KEGNRPEDPE YDPRTIYIPS
RAWNEFTPFE KQFWEIKQNH YDTVLFFQKG KFYELYENDA MIGHQEFDLK LTDRVKMKMV
GVPEQTFEFW AAKFLAAGYK VGKVEQAETA IGMEMRTKGG GKEIVRRELA QVFTNGTIVD
GSYLTSDEAN HCVSIKEFTG DANTPSAFGI CVMDASTGEF NLTAFEDDIC RTRLETMFRQ
IRPKELVFAK GNLSVPTTRL LRNILPASTL WQSFKLGKEF MSKEDAVEAL REIFSSDGSG
DPELPEAITA MMDQPLAMEA LGGMIFYLRS LNLDKDLISQ KNFNIYDPIR NGKSLVLDGQ
TLAHMEVLMN NEGTEAGTLL SLLQRCLTPF GKRLFRIWLT APLRDVKAIN ERLDAVDDLI
ANPAFTGQFT QLVRGLPDLE RLVSRIHAGS IRQTDFLKVV DQFSNIQSAI DLLVGESEKF
ASSSVRGLLR TAPDLSANIA HLKSMYEVEN TTKTITILPT PGADPDCDDA KEAVEEIEQK
LELLKQQAMK TLGTRDVSFW SNAQSNKEIF HLLVPASAKV PKNWTKCGGT KKQTRYITPQ
TQPVIREMQE ARETEATAKR NFFRKLLAEF DSDRTAWLSM VRVVAELDCL VSLAKASHDM
DEPKCRPEFM ETEQAFVDFG DLRHPSMCLQ RDFIANNVQL GADVARTTLL TGPNMAGKST
LLRMTAAAVI MAQLGCYVPA AHARLSPIDK IQTRMGAYDN MFASASTFKV ELDECSKILR
EAGPKSLVIL DELGRGTSTF DGMAIAGAVL HQLATHTLPL GFFATHYGSL TDEYAYHPNI
RNMHMQVHVD DSDGVVFLYK LITGHAESSH GTHVAKLAGV PKSVIARADE VSAQFFRAFQ
EKLESRRQSA LPLPAQADFA WLVKLASDKA EETTATVAQQ LDVVCRATTK YEYAA
//
