ID A0A0J0YSY1_9NEIS Unreviewed; 382 AA.
AC A0A0J0YSY1;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Hemolysin D {ECO:0000313|EMBL:KLT73219.1};
GN ORFNames=PL75_04320 {ECO:0000313|EMBL:KLT73219.1};
OS Neisseria arctica.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC Neisseria.
OX NCBI_TaxID=1470200 {ECO:0000313|EMBL:KLT73219.1, ECO:0000313|Proteomes:UP000036027};
RN [1] {ECO:0000313|EMBL:KLT73219.1, ECO:0000313|Proteomes:UP000036027}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KH1503 {ECO:0000313|EMBL:KLT73219.1,
RC ECO:0000313|Proteomes:UP000036027};
RA Hansen C.M., Hueffer K., Choi S.C.;
RT "Genome of a novel goose pathogen.";
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KLT73219.1}.
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DR EMBL; JTDO01000005; KLT73219.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0J0YSY1; -.
DR STRING; 1470200.PL75_04320; -.
DR PATRIC; fig|1470200.3.peg.2012; -.
DR Proteomes; UP000036027; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR043602; CusB_dom_1.
DR InterPro; IPR032317; HlyD_D23.
DR PANTHER; PTHR30386; MEMBRANE FUSION SUBUNIT OF EMRAB-TOLC MULTIDRUG EFFLUX PUMP; 1.
DR PANTHER; PTHR30386:SF19; MULTIDRUG EXPORT PROTEIN EMRA-RELATED; 1.
DR Pfam; PF00529; CusB_dom_1; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 3.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022519};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000036027};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 16..38
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 52..282
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT DOMAIN 283..340
FT /note="Cation efflux system protein CusB"
FT /evidence="ECO:0000259|Pfam:PF00529"
SQ SEQUENCE 382 AA; 41654 MW; 278DB4D80AD27444 CRC64;
MTVRKTGISG HRKRNLTLLT LFFIIIGLGF LLIYLLVWQH QEETEDAYVA GHLVQITPQV
AGTVRKVAVE DTDIVKKGDV LVILDDSDFQ LAYDRAQSEL IQAIRQYQQQ NAGNAEAQAR
VLAAKADLAK AQADLRRRES LAGTDAISGE ELSHARAAVV QAQTALKAVQ AQESSVQAAL
GKNIPLRQQP AVQTAVSHIK DAWLNLQRTQ IRAPTSGQIA KRNIQIGQKT TPGAPMMAVV
PLQDLWVDAN FKEVQLSKMR IGQPVVMTSD LYGNKVKYRG KIMGLSAGTG SAFSMLPPQN
ATGNWIKVVQ RVPVRISLDP QELQKNPLRV GLSMSVTVDT KNENGQNMAA AAAKNIIAPE
ADPVDWAAAD ALIDQIFEKY AK
//
