ID A0A0J1FDR0_9FIRM Unreviewed; 796 AA.
AC A0A0J1FDR0;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Signal transduction histidine-protein kinase/phosphatase DegS {ECO:0000313|EMBL:KLU61562.1};
DE EC=2.7.13.3 {ECO:0000313|EMBL:KLU61562.1};
DE EC=3.1.3.- {ECO:0000313|EMBL:KLU61562.1};
GN Name=degS_2 {ECO:0000313|EMBL:KLU61562.1};
GN ORFNames=CEB3_c19940 {ECO:0000313|EMBL:KLU61562.1};
OS Peptococcaceae bacterium CEB3.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Peptococcaceae.
OX NCBI_TaxID=999898 {ECO:0000313|EMBL:KLU61562.1, ECO:0000313|Proteomes:UP000035957};
RN [1] {ECO:0000313|EMBL:KLU61562.1, ECO:0000313|Proteomes:UP000035957}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CEB3 {ECO:0000313|EMBL:KLU61562.1,
RC ECO:0000313|Proteomes:UP000035957};
RA Poehlein A., Petzsch P., Johnson B.D., Schloemann M., Daniel R.,
RA Muehling M.;
RT "Genome sequence of the moderately acidophilic sulfate reducing
RT Peptococcaceae bacterium strain CEB3.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KLU61562.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LDXJ01000053; KLU61562.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0J1FDR0; -.
DR STRING; 999898.CEB3_c19940; -.
DR PATRIC; fig|999898.3.peg.2237; -.
DR OrthoDB; 9781904at2; -.
DR Proteomes; UP000035957; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR041489; PDZ_6.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR PANTHER; PTHR24421:SF37; SIGNAL TRANSDUCTION HISTIDINE-PROTEIN KINASE_PHOSPHATASE UHPB; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07730; HisKA_3; 1.
DR Pfam; PF17820; PDZ_6; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000313|EMBL:KLU61562.1};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:KLU61562.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000035957};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:KLU61562.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 122..140
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 152..168
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 180..199
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 211..235
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 241..261
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 273..295
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 307..328
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 340..358
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 370..391
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 23..95
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 698..789
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 405..432
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 796 AA; 88862 MW; 90F9C9C52839AD37 CRC64;
MRKVLSGRPP YYLASAVFLL ISVIYLGVML DRAYVGLELA DVNGRWIVVG SDPNGAAYKA
GVRVGDRILE INQKDPGAYG DVRTWNEAEG ITTLKFRGPG QSGGRVVKVQ QGAVRLESLS
EIFMIILGYL FANLGLLAWL RRPLWGPARL LFWLNWSIAL ALVLAPASGR DLLFAREFEY
ITLSFVPVLM TKFFSVFPVE RETRINRYAG RVLICVSIAI VTLTVLQSAG VLQAAAWLRK
FALATVLTGI LISLGNLAAI RRLPGRTPEK NQAGILLLGT VIGFLPFTLL TALPLMCNFP
PIENTELSYL FVAAVPITWS YVIVKRYLPD SRRLMRRVCS FSLAVAVVSF VLTYAFFFAG
VLKSLDLEGF LAVFSLTTVV SLSFTGVRLT FAELFKRLGF LAVEQEGVDQ RVSQLNERLV
SLREEEDRIL EEVATSLGVE GALLIVENAD GRGLKKAVGR FLARPDEQTM LERYFQTDKR
GQLGTTRLPE DWPAEICIRV AGKDFVSGTF LGHRYSRIKF QGQELPSLTL ICGQTVRQLS
SAQAIEELSQ EIRNMVQRSE IYERKIRRLR GITGSLFKNV EQERKTIARD LHDGPLQLAL
DLSRWLDELA DHFADGEESC HGKAIAHMRE VSQNLNFELR TICSDLRPPS LTDLGLVYSV
RILCEEKMES EPFEFSLDCV GISEKTRLRE EVELVAYRFL QEGIANAMRH TGSGKINLGI
ELKESELELV VRDSGKGFDP VRIDDLPLTN EHLGLVGMRE RIESLGGKLH ICSVPCQGTV
LKACIPTSGR ERKRVV
//
