ID A0A0J1G4H2_9FIRM Unreviewed; 1318 AA.
AC A0A0J1G4H2;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Diguanylate cyclase {ECO:0008006|Google:ProtNLM};
GN ORFNames=RHS_3740 {ECO:0000313|EMBL:KLU70474.1};
OS Robinsoniella sp. RHS.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Robinsoniella.
OX NCBI_TaxID=1504536 {ECO:0000313|EMBL:KLU70474.1, ECO:0000313|Proteomes:UP000036477};
RN [1] {ECO:0000313|EMBL:KLU70474.1, ECO:0000313|Proteomes:UP000036477}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RHS {ECO:0000313|EMBL:KLU70474.1};
RX PubMed=25284151; DOI=10.1016/j.cell.2014.09.008;
RA Seedorf H., Griffin N.W., Ridaura V.K., Reyes A., Cheng J., Rey F.E.,
RA Smith M.I., Simon G.M., Scheffrahn R.H., Woebken D., Spormann A.M.,
RA Van Treuren W., Ursell L.K., Pirrung M., Robbins-Pianka A., Cantarel B.L.,
RA Lombard V., Henrissat B., Knight R., Gordon J.I.;
RT "Bacteria from diverse habitats colonize and compete in the mouse gut.";
RL Cell 159:253-266(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KLU70474.1}.
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DR EMBL; JNGB01000041; KLU70474.1; -; Genomic_DNA.
DR PATRIC; fig|1504536.3.peg.4963; -.
DR Proteomes; UP000036477; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 2.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.450.40; -; 2.
DR Gene3D; 3.30.70.270; -; 2.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 2.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR PANTHER; PTHR33121:SF71; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF00990; GGDEF; 2.
DR Pfam; PF08447; PAS_3; 2.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 2.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55781; GAF domain-like; 2.
DR SUPFAM; SSF55073; Nucleotide cyclase; 2.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 2.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Reference proteome {ECO:0000313|Proteomes:UP000036477}.
FT DOMAIN 296..429
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 940..1066
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 1065..1318
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 1318 AA; 152465 MW; FE9CA775846D9FF8 CRC64;
MEESSMKSQN ITDDFRVGIV KCRKDEYLSI KEVNKGFLRL FGYKVADLEE CFGSGLVNII
HADDRQKLLL NIKESNQNKD RIVCCCRMVC KDRTYLWVQY FGQSIKDVSG EEIILGMITE
RIMDQEEAKG FLHTKCGVGP FLKDLDVASE QSEVMIFEWD VVTDTMAYSS DFQNSAHIIR
EISSHLVSSH YTHPDDKKVL MNLRESVKQG KLYSTSEFRI RNEKNEYIWY RIHAITQYDS
DEKPAKAVGM MFCINEEMQV IEQLRARAER DVLTGLYNRE ETEERIKRHL QGKPANSCAL
LMIDTDNFKQ INDTKGHMLG DVVLSELAAS MKNRMRKSDI VGRVGGDEFI IFMKDIASRE
AASKKTEELL QGFSHLFKNE KMAVQITCSI GIAVYPEDGN EFKTLYRHAD QALYQAKIQG
KNQYVMYDYQ HSYQIEEAGY SNLVTAIDSE IKSSGQQSNV LSDIFKILYR TEDTEQAINL
TLEIVGRRFD VSRAYIFEST EDGKYHSNTY EWCNKGINPE MENLQNIDAS EAGDYKTMFD
DNSIFYCRDT HLLPTTQREL LEKQGIYSTL QCAFWKEKEF AGFVGFDECT GLRLWTREEV
DVLSMVSQML TTFLQKKRVM ERNAEMELQM RTILDSQSSC IYIVEKNTFA LLFLNSKAKE
FRQGIRQGEC CYSVLFDKKE PCGFCPLLED RVWEGKMAED SIHSKIHASS TKWFGKEAYL
VSFRIESNAA LLNTRQDMEH HITAEKSIVD CIQCLTSSEY LEDAIEYVLE IVQDYYQSDR
VYIIEIDESM GVVSNTYEIC AEGVEPQINM LQNVPLEAIT FWMEQFELKD YINIENVDEL
GDERHLEFEI LKEQGINSLM AIPLYVKGEM KGFLGIDDPK IHKENFYYLK ELSYFLENEI
SKNSLKKKLV KMSYQDSMTG LENRNSYMTY CDDFLESHPA PVGVAFMDIN GLKKLNDLKG
HLCGNMLINH IAEKMKEFFP KERCFRLSGD EFLIVTQSMS YDEFRKQLTG LTESLTEDGH
SSIAIGTTWS DVEADLIDLV NKADRLMYIN KQDYYKETKD ISVTKIPLLR GLLESILNNE
YLIYLQPKLN VQTGKIDSAE VLVRYREKDG TISSPAKFIP MLESEGLISN IDFFVMEEVC
RLLTKWKAAH LSDMKLAINF SRITLFDHHF LKQFQDIFER YSLRPGQLEV EVTETQETLN
KKLMARLLDE LSNRGFRIAL DDFGVEYSSY EFLLMANFNL MKIDKGIVQR YGETKKCETL
MKHIVDMGHD LGISCCAEGV ETEEQFHFIK SIGCDYIQGY LIGKPVSIEQ FEIKYLEK
//
