ID A0A0J1GF01_9FIRM Unreviewed; 652 AA.
AC A0A0J1GF01;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=EAL domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=RHS_0192 {ECO:0000313|EMBL:KLU74097.1};
OS Robinsoniella sp. RHS.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Robinsoniella.
OX NCBI_TaxID=1504536 {ECO:0000313|EMBL:KLU74097.1, ECO:0000313|Proteomes:UP000036477};
RN [1] {ECO:0000313|EMBL:KLU74097.1, ECO:0000313|Proteomes:UP000036477}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RHS {ECO:0000313|EMBL:KLU74097.1};
RX PubMed=25284151; DOI=10.1016/j.cell.2014.09.008;
RA Seedorf H., Griffin N.W., Ridaura V.K., Reyes A., Cheng J., Rey F.E.,
RA Smith M.I., Simon G.M., Scheffrahn R.H., Woebken D., Spormann A.M.,
RA Van Treuren W., Ursell L.K., Pirrung M., Robbins-Pianka A., Cantarel B.L.,
RA Lombard V., Henrissat B., Knight R., Gordon J.I.;
RT "Bacteria from diverse habitats colonize and compete in the mouse gut.";
RL Cell 159:253-266(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KLU74097.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JNGB01000001; KLU74097.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0J1GF01; -.
DR PATRIC; fig|1504536.3.peg.198; -.
DR Proteomes; UP000036477; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR PANTHER; PTHR33121:SF71; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000036477};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 45..70
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 76..100
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 112..132
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 152..174
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 186..201
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 258..389
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 398..652
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 652 AA; 74213 MW; 0473BEB516FE147F CRC64;
MLDDKEEEGE VLRWNVAAEC ISVVFLVIIW SYARKGDLLP SLKNRLFQCC FLATFCAMVS
NILSTAALAF PHYVPYQFSW AVTIIYFIST PLMGMAYFFY TTATVYENHK GISKVIGWSS
IPGILYLLLA IANLPCKLLF NIMPDGTYTQ GPLIITTYLV FYIYSLAAMV IVLIKHSWIE
KKIRRILAIF PFIAMIVIVI QQLFPNILLS GSAATSALLL IYLYLQNKQI SFDYLTDIPN
RQEFLKMLEL MIRKNEKTSF TIIVLSLRGF KQINDTFGQQ SGDAFLKAVS AYLHTIIEKQ
YLFRFSGDEF AILEKNTEKE KIYHIIDTLK ERMTIPWTVK EYSCIIQSAM GIVSYPETAD
SVEGLINGIE YAVSKAKQDR TKAVCYCGQE MMRELRRRIQ IAEILKAKLE SNDFDVYYQP
IVDTRTNKFV LAESLLRIPS SPIGAVYPDE FIPIAEETGM IIEMTYQILA KVCRYINRLM
EQGIELDGIH VNFSTVQFTQ IDLAEKVLNI IEEHHTPYSK IKIEITESVL AESAQLVIGF
AEEMHKHGVM MGLDDFGTGY SNIVSVMETP LDVIKIDKSL VWSSMTVPKS AGMLRSMTGI
FHDMDLKVLA EGVETPEQDQ FIKESGIDYI QGFLYARPMP GDDMLKLLQA EK
//
