ID A0A0J1H8Z4_9GAMM Unreviewed; 791 AA.
AC A0A0J1H8Z4;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=endopeptidase La {ECO:0000256|PROSITE-ProRule:PRU01122};
DE EC=3.4.21.53 {ECO:0000256|PROSITE-ProRule:PRU01122};
GN ORFNames=ABT57_15330 {ECO:0000313|EMBL:KLV08174.1};
OS Photobacterium ganghwense.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Photobacterium.
OX NCBI_TaxID=320778 {ECO:0000313|EMBL:KLV08174.1, ECO:0000313|Proteomes:UP000035909};
RN [1] {ECO:0000313|EMBL:KLV08174.1, ECO:0000313|Proteomes:UP000035909}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 22954 {ECO:0000313|EMBL:KLV08174.1,
RC ECO:0000313|Proteomes:UP000035909};
RA Machado H., Gram L.;
RT "Photobacterium galathea sp. nov.";
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of proteins in presence of ATP.; EC=3.4.21.53;
CC Evidence={ECO:0000256|PROSITE-ProRule:PRU01122};
CC -!- SIMILARITY: Belongs to the peptidase S16 family. {ECO:0000256|PROSITE-
CC ProRule:PRU01122}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KLV08174.1}.
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DR EMBL; LDOU01000015; KLV08174.1; -; Genomic_DNA.
DR RefSeq; WP_047886063.1; NZ_PYMI01000004.1.
DR AlphaFoldDB; A0A0J1H8Z4; -.
DR PATRIC; fig|320778.3.peg.3335; -.
DR OrthoDB; 9758568at2; -.
DR Proteomes; UP000035909; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004176; F:ATP-dependent peptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0030163; P:protein catabolic process; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR041699; AAA_32.
DR InterPro; IPR046844; Lon-like_helical.
DR InterPro; IPR008269; Lon_proteolytic.
DR InterPro; IPR027065; Lon_Prtase.
DR InterPro; IPR046843; LonB_AAA-LID.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR PANTHER; PTHR10046:SF46; ARCHAEAL LON PROTEASE; 1.
DR PANTHER; PTHR10046; ATP DEPENDENT LON PROTEASE FAMILY MEMBER; 1.
DR Pfam; PF13654; AAA_32; 1.
DR Pfam; PF05362; Lon_C; 1.
DR Pfam; PF20436; LonB_AAA-LID; 1.
DR Pfam; PF20437; LonC_helical; 1.
DR PRINTS; PR00830; ENDOLAPTASE.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR PROSITE; PS51786; LON_PROTEOLYTIC; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Hydrolase {ECO:0000256|PROSITE-ProRule:PRU01122};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01122}; Reference proteome {ECO:0000313|Proteomes:UP000035909};
KW Serine protease {ECO:0000256|PROSITE-ProRule:PRU01122}.
FT DOMAIN 567..762
FT /note="Lon proteolytic"
FT /evidence="ECO:0000259|PROSITE:PS51786"
FT COILED 213..244
FT /evidence="ECO:0000256|SAM:Coils"
FT ACT_SITE 657
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01122"
FT ACT_SITE 700
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01122"
SQ SEQUENCE 791 AA; 88626 MW; 2D5B7F6280DDA9BD CRC64;
MTIKTLSSDK LYRVSELHGL PEDCKSTKNL TPLDEIVGQE RAQQAVEFAM SIKEKGYNIY
AIGRNGLGKR TMVLRYLNRH DPNGSGHPQH DWCYVANFEE SRNPKVLKMP AGRGTQFKKD
VEKMMTKLVK ALPLAFDNEV YYSRSEKLKN QLDQKQQGAL LALTQEAKEH SISLTVTMAG
EYQLVALNGE EPHTEESFAQ LSDKEQKVFE DTINALEKKL RSIVRELTEL EEDFSEKMQK
LNEEIALEVV SHFIHDLLIE YKSLPEVKNY LKAMRKDILE NLDIFLEESE EDVALAYATL
DKKMPRRYQV NVLVANDTET KFPIVVEESP NYHSIFGYVE NATYKGTIFT DFSLIRSGSL
HRANGGVLLM DAVKVLERPY VWDGLKRALR SRKLSVSSLE KEVTLSGTIS LDPEPIPLSV
KIILFGDYQT YQLLQHYDPE FSELFRVTAD FEDEMCRTDE SEAQYAKFIS SIVNDNNMLH
CDRKAIARII EYSSRQADDQ NKLSLHSADI ANLLRESNYA AKSSNATMIR ANHVEQALHS
QEKRVSRLKD HVMQTFTNGT TLIDTEGAVV GQINGLSVIS TSDYQFGAPN RITATTSYGE
GGVFDIERSV DLGGRIHSKG VMILSAYLAS IFGRSSRVPL TTHLTFEQSY GGVDGDSASM
AELCAIVSAY SQIPLRQDVA ITGSMNQFGQ AQPIGGVNEK IEGFFDVCTI KGRHAAQGVI
IPQSNAHNLM LRKDVVEAVE KGEFHIWAIS HVTDAIEIMT GKQAGQASLD GTYPVESVLG
QAQMKLNALR R
//
