ID A0A0J5FWC7_9GAMM Unreviewed; 394 AA.
AC A0A0J5FWC7;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Multidrug transporter {ECO:0000313|EMBL:KMJ46287.1};
GN ORFNames=AB204_04640 {ECO:0000313|EMBL:KMJ46287.1};
OS Xenorhabdus khoisanae.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Xenorhabdus.
OX NCBI_TaxID=880157 {ECO:0000313|EMBL:KMJ46287.1, ECO:0000313|Proteomes:UP000036277};
RN [1] {ECO:0000313|EMBL:KMJ46287.1, ECO:0000313|Proteomes:UP000036277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MCB {ECO:0000313|EMBL:KMJ46287.1,
RC ECO:0000313|Proteomes:UP000036277};
RA Naidoo S., Featherston J., Gray V.M.;
RT "Draft Whole-Genome Sequence of the Entomopathogenic Bacterium Xenorhabdus
RT khoisanae.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KMJ46287.1}.
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DR EMBL; LFCV01000026; KMJ46287.1; -; Genomic_DNA.
DR RefSeq; WP_047962222.1; NZ_LFCV01000026.1.
DR AlphaFoldDB; A0A0J5FWC7; -.
DR STRING; 880157.AB204_04640; -.
DR PATRIC; fig|880157.4.peg.963; -.
DR OrthoDB; 9811754at2; -.
DR Proteomes; UP000036277; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1990961; P:xenobiotic detoxification by transmembrane export across the plasma membrane; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR InterPro; IPR043602; CusB_dom_1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR005694; MFP_proteobact.
DR NCBIfam; TIGR00998; 8a0101; 1.
DR PANTHER; PTHR30386; MEMBRANE FUSION SUBUNIT OF EMRAB-TOLC MULTIDRUG EFFLUX PUMP; 1.
DR PANTHER; PTHR30386:SF19; MULTIDRUG EXPORT PROTEIN EMRA-RELATED; 1.
DR Pfam; PF00529; CusB_dom_1; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 2.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022519};
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 24..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 37..347
FT /note="Cation efflux system protein CusB"
FT /evidence="ECO:0000259|Pfam:PF00529"
FT DOMAIN 62..293
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT COILED 88..115
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 394 AA; 43500 MW; D5C380EB06A9E3FB CRC64;
MQLSPSNPKT SQKSSNKKRQ RRNIITSLTL LFLTLGVIYT VYWFLVLRHH QETDNAYVTG
NQVQIMSQVA GSVITVNFDN TDYVKSGHVL IQLDARDAEL ALKKAENELA NTVRITHQRM
IDSKKYQATI ELKKIALKKA QSDLNRREVL GAKEMIGKEE LQHMRENVST AQADLDIAIA
QYKSNQATIL DTPLEKQPAV EKAASGVRDA WLALQRTKIV SPVDGYVARR SVQVGSRINS
GTPLMAIVPA NNMWVEANFK ETQLANMRIG QPATIISDFY GKNVVYTGKV AGIDMGTGSA
FSLLPAQNAS GNWIKVIQRL PVRIEIDAEQ LKQHPLRIGL STTINVDTAN TDGTTLATTE
RSLPAYHTNA LTIDMVPANQ IVTDVINSNL GNPI
//
