ID A0A0J5FWC8_9GAMM Unreviewed; 164 AA.
AC A0A0J5FWC8;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Leucine-responsive regulatory protein {ECO:0000256|ARBA:ARBA00039227};
GN ORFNames=AB204_03245 {ECO:0000313|EMBL:KMJ46506.1};
OS Xenorhabdus khoisanae.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Xenorhabdus.
OX NCBI_TaxID=880157 {ECO:0000313|EMBL:KMJ46506.1, ECO:0000313|Proteomes:UP000036277};
RN [1] {ECO:0000313|EMBL:KMJ46506.1, ECO:0000313|Proteomes:UP000036277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MCB {ECO:0000313|EMBL:KMJ46506.1,
RC ECO:0000313|Proteomes:UP000036277};
RA Naidoo S., Featherston J., Gray V.M.;
RT "Draft Whole-Genome Sequence of the Entomopathogenic Bacterium Xenorhabdus
RT khoisanae.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Mediates a global response to leucine. Exogenous leucine
CC affects the expression of a number of different operons; lrp mediates
CC this effect for at least some of these operons. For example it is
CC regulator of the branched-chain amino acid transport genes.
CC {ECO:0000256|ARBA:ARBA00037041}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KMJ46506.1}.
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DR EMBL; LFCV01000018; KMJ46506.1; -; Genomic_DNA.
DR RefSeq; WP_004256338.1; NZ_LFCV01000018.1.
DR AlphaFoldDB; A0A0J5FWC8; -.
DR SMR; A0A0J5FWC8; -.
DR STRING; 880157.AB204_03245; -.
DR GeneID; 84569092; -.
DR PATRIC; fig|880157.4.peg.674; -.
DR OrthoDB; 166264at2; -.
DR Proteomes; UP000036277; Unassembled WGS sequence.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProt.
DR CDD; cd00090; HTH_ARSR; 1.
DR Gene3D; 3.30.70.920; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011991; ArsR-like_HTH.
DR InterPro; IPR000485; AsnC-type_HTH_dom.
DR InterPro; IPR011008; Dimeric_a/b-barrel.
DR InterPro; IPR019888; Tscrpt_reg_AsnC-like.
DR InterPro; IPR019887; Tscrpt_reg_AsnC/Lrp_C.
DR InterPro; IPR019885; Tscrpt_reg_HTH_AsnC-type_CS.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30154; LEUCINE-RESPONSIVE REGULATORY PROTEIN; 1.
DR PANTHER; PTHR30154:SF0; LEUCINE-RESPONSIVE REGULATORY PROTEIN; 1.
DR Pfam; PF01037; AsnC_trans_reg; 1.
DR Pfam; PF13412; HTH_24; 1.
DR PRINTS; PR00033; HTHASNC.
DR SMART; SM00344; HTH_ASNC; 1.
DR SUPFAM; SSF54909; Dimeric alpha+beta barrel; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00519; HTH_ASNC_1; 1.
DR PROSITE; PS50956; HTH_ASNC_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 12..73
FT /note="HTH asnC-type"
FT /evidence="ECO:0000259|PROSITE:PS50956"
SQ SEQUENCE 164 AA; 18861 MW; 1735D96F61767197 CRC64;
MIDNKKRPGK DLDRIDRNIL NELQKDGRIS NVELSKRVGL SPTPCLERVR RLERQGFISG
YTALLNPHYL DASLLVFVEI TLNRGAADVF EQFNTAVQKL EEIQECHLVS GDFDYLLKTR
VPDMSAYRKL LGETLLRLPG VNDTRTYVVM EEVKQSNRLV IKTR
//
