ID A0A0J5GPC4_9BACI Unreviewed; 1741 AA.
AC A0A0J5GPC4;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE RecName: Full=Carrier domain-containing protein {ECO:0000259|PROSITE:PS50075};
DE Flags: Fragment;
GN ORFNames=AB685_24515 {ECO:0000313|EMBL:KMJ55958.1};
OS Bacillus sp. LL01.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=1665556 {ECO:0000313|EMBL:KMJ55958.1, ECO:0000313|Proteomes:UP000036436};
RN [1] {ECO:0000313|EMBL:KMJ55958.1, ECO:0000313|Proteomes:UP000036436}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LL01 {ECO:0000313|EMBL:KMJ55958.1,
RC ECO:0000313|Proteomes:UP000036436};
RA Vilo C., Galetovic A., Araya J., Gomez Silva B., Dong Q.;
RT "Draft Genome Sequence of a Bacillus Bacterium from the Atacama Desert
RT Wetlands Metagenome.";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC Evidence={ECO:0000256|ARBA:ARBA00001957};
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KMJ55958.1}.
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DR EMBL; LFEL01000076; KMJ55958.1; -; Genomic_DNA.
DR PATRIC; fig|1665556.3.peg.5988; -.
DR OrthoDB; 9765680at2; -.
DR Proteomes; UP000036436; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd05930; A_NRPS; 1.
DR CDD; cd19531; LCL_NRPS-like; 1.
DR Gene3D; 3.30.300.30; -; 2.
DR Gene3D; 3.40.50.980; -; 2.
DR Gene3D; 1.10.1200.10; ACP-like; 2.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 2.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 2.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR010060; NRPS_synth.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR NCBIfam; TIGR01720; NRPS-para261; 1.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 2.
DR Pfam; PF00668; Condensation; 2.
DR Pfam; PF00550; PP-binding; 2.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 2.
DR SUPFAM; SSF47336; ACP-like; 2.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 4.
DR PROSITE; PS00455; AMP_BINDING; 1.
DR PROSITE; PS50075; CARRIER; 2.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 3: Inferred from homology;
KW Antibiotic biosynthesis {ECO:0000256|ARBA:ARBA00023194};
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
FT DOMAIN 171..246
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 1206..1280
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KMJ55958.1"
SQ SEQUENCE 1741 AA; 199535 MW; 266439C3732EA6AA CRC64;
CGIGIPGELC ITGSGVSRGY LNSEELTREK FVENPFGEGK MYKSGDLVRW LPDGNIEFLG
RIDHQVKIRG FRVELQEIEE VFNKQAGVKE TVVLAKELDE GVQALFAYVV MKENEALDLA
AIKEGARKEL PEYMIPSYMM AIDEIPLTVN GKTDKKALPD IGFERQDDYI APSNPIEEAL
CKVFEEVLGV EKVGIKDNFF ELGGHSLRAM NVVNLLEEKL KKRIEVKYIF ESPTPESLSK
RIEAMEEGNY QPIPRADWKE AYPMSSAQKR LFLINQMDET ELSYNMPVCL SYTGKVQEEK
VQHVFDELVK RHESLRTSFH FEGEEAIQKI AAESRILVET EERDASPFPE VYLEEFVRPF
DLREAPLLRV KIIKTNDNQG YLLFDMHHII SDGMSMNILI KDFCQLYEGN ALASLDVHYK
DYSEWMGKKD LGKQEKYWLD THKERPYVLD FPLDAKRPQL QSFKGDSVKE RLGKDITVEL
KTFARREGYT DYMVMLGALM VCISKYSRQE DIVIGSPISG RTHPDTASIV GMFVNTLAMR
GYPEKEKSIK AFLDEIKEHS LNSYENQEYP FEELVEKTVT NRDLSRNPMF DIMFTLQNNE
EVIFETKDFT LGTISQKPVA KFDLDFHMEY GNEHYNLNLI YSQALFNKES MIILVKQYFN
ILREIVVNPE RTIGELTLSN EAETLTILTD FNHTEKTMEK GKTVQELFEE AVERNPGRIA
IVDGSIELSY EEFNHKINHL ADKLRSLGVK PGERVAILSK RSAAMMVGIY AVIKAGGSYI
PIDPDYPLER KKFVLDDSEP KIILRGESEW LSKEELGSVN STILDLDEEC HVSVHQIDNL
PKIHNENDLV YIMYTSGTTG KPKGVMVKHS NLFNYLEYGK RSYLPEEVSA PLFTSVGFDL
TVTTLFLPLC SGGKLVIKEH DVEETIREIF QEDKYSFAKM TPAHLKMAVQ ERPKRLKNLH
TLIVGGEELG TRLAQDILDK FGDHLKIHNE YGPTEATVGS CDFIFPGLVH GEEAKGVSIG
KAIDNAKIFI MDKDKLCDIN VPGELCISGA GVSKGYFNQE ELTKEKFVDN PFGEGIIYRT
GDLARWLPNG RLEYLGRIDE QFSIRGYRIE PGEIEEVLRK QEGIEDAVVI AKESGEDKTL
VAFVVMETDK ELDISRLKGD LRKELPSYMI PTYXAAIEGI PLTINGKIDK NALPAIEYNR
QDEYIAPRNP VEEILCSIFE EVLGMEQVGI RDNFFELGGD SIKAIRVVPK ARELGYEISF
GDIMRLHCVE NLAKEVKEIT VHYEQGEVNG EIDLSPIQKM FFDWDLTNRN HYNQAVMLES
KNSLSASVIR DVLDVLVETH DMLRVVLKDH HPTILPMDLS KKYTLKVFEC EDWENLEDKM
EEESTKLQRT MNLEHGPLMK VALFKTNDCD YLMIAIHHFI IDGVSWRILL EDFVTSYGLA
MENKEIVLPN KTASYKQWTN AIEEYSNSTI FVEESKYWEE VYNHITKSQL ERETNQPFNG
FGHESFDIDS EITRKLIFES FKAYGTEVND LLLTSLMLAM KKWKKMNKVT IDLESHGRND
IVSNIHLDRT LGWFTSIYPI HLQSFSSMKE SIVETKEMLR RVPNLGIGYS LWKQQNPKER
NLNSSIAFNY MGDMDLSISD EYGYQMSSKN PGVTIDENNE LLYDISIDIQ KIDKKLYGYV
NYKEDKFTKE SIGEFCRLYA ESLIEVINHC LTQEEVVATP SDFDALEMEM EELEDILNVF
S
//
