ID A0A0J5QBQ6_9RHOB Unreviewed; 818 AA.
AC A0A0J5QBQ6;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Malic enzyme {ECO:0000313|EMBL:KMK66313.1};
DE EC=1.1.1.40 {ECO:0000313|EMBL:KMK66313.1};
GN ORFNames=IMCC21224_111163 {ECO:0000313|EMBL:KMK66313.1};
OS Puniceibacterium sp. IMCC21224.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Puniceibacterium.
OX NCBI_TaxID=1618204 {ECO:0000313|EMBL:KMK66313.1, ECO:0000313|Proteomes:UP000036046};
RN [1] {ECO:0000313|EMBL:KMK66313.1, ECO:0000313|Proteomes:UP000036046}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IMCC21224 {ECO:0000313|EMBL:KMK66313.1,
RC ECO:0000313|Proteomes:UP000036046};
RA Cho J.-C., Yang S.-J., Kang I.;
RT "Complete genome sequence of IMCC21224 belonging to the
RT Alphaproteobacteria.";
RL Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KMK66313.1}.
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DR EMBL; LDPY01000001; KMK66313.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0J5QBQ6; -.
DR STRING; 1618204.IMCC21224_111163; -.
DR PATRIC; fig|1618204.4.peg.1183; -.
DR Proteomes; UP000036046; Unassembled WGS sequence.
DR GO; GO:0016746; F:acyltransferase activity; IEA:InterPro.
DR GO; GO:0004473; F:malate dehydrogenase (decarboxylating) (NADP+) activity; IEA:UniProtKB-EC.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0008948; F:oxaloacetate decarboxylase activity; IEA:UniProtKB-EC.
DR CDD; cd05311; NAD_bind_2_malic_enz; 1.
DR Gene3D; 3.40.50.10950; -; 1.
DR Gene3D; 3.40.50.10750; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
DR Gene3D; 3.40.50.10380; Malic enzyme, N-terminal domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR046346; Aminoacid_DH-like_N_sf.
DR InterPro; IPR012301; Malic_N_dom.
DR InterPro; IPR037062; Malic_N_dom_sf.
DR InterPro; IPR012302; Malic_NAD-bd.
DR InterPro; IPR045213; Malic_NAD-bd_bact_type.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR042113; P_AcTrfase_dom1.
DR InterPro; IPR042112; P_AcTrfase_dom2.
DR InterPro; IPR002505; PTA_PTB.
DR PANTHER; PTHR43237; NADP-DEPENDENT MALIC ENZYME; 1.
DR PANTHER; PTHR43237:SF4; NADP-DEPENDENT MALIC ENZYME; 1.
DR Pfam; PF00390; malic; 1.
DR Pfam; PF03949; Malic_M; 1.
DR Pfam; PF01515; PTA_PTB; 1.
DR SMART; SM01274; malic; 1.
DR SMART; SM00919; Malic_M; 1.
DR SUPFAM; SSF53223; Aminoacid dehydrogenase-like, N-terminal domain; 1.
DR SUPFAM; SSF53659; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:KMK66313.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000036046}.
FT DOMAIN 81..214
FT /note="Malic enzyme N-terminal"
FT /evidence="ECO:0000259|SMART:SM01274"
FT DOMAIN 226..463
FT /note="Malic enzyme NAD-binding"
FT /evidence="ECO:0000259|SMART:SM00919"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 818 AA; 87673 MW; 3875DAA06EEAEB8D CRC64;
MLRSQQAECK RAREPTPPAL WSATAPDVPP DSDPTLSACG KTVYQVLQNA ATGAALGGPE
MSDANDSLRQ AALAYHEFPK PGKLEIRATK PLANGRDLAR AYSPGVAEAC LEIKADPANA
ARYTARGNLV AVVTNGTAVL GLGNIGALAS KPVMEGKAVL FKKFANIDCF DIEVNEPDPV
KLADIVCALE PTFGAINLED IKAPDCFIVE KLCRERMNIP VFHDDQHGTA IVVGAAARNA
LFVADKSFEE IKIVSTGGGA AGIACLNMLV KLGVKRENIW LCDVHGLVYE GRDVDMNPQK
TCFAQATDKR TLDDVIDGAD LFLGLSGPNV LKPEMVARMA ARPIIFALAN PNPEIMPDVA
RSVVPDAIIA TGRSDFPNQV NNVLCFPFIF RGALDVGATE INDEMEIACV EGIAAMARAT
TSAEAAAAYK GEQLTFGADY LIPKPFDPRL SGVVSTAVAK AAMDTGVAAR PLDDLVAYKA
RLDASVYKSA LLMRPIFHAS ASAERRIVFA EGEDERVLRA AQAILEETVE TPILIGRPDV
IEMRCERLGL NIRPGRDFHI VNPENDPRYR DYWESYHSLM ARRGVSPDLA RAIMRTNTTA
IGAVMVNMGD ADSLICGTFG EYRWHLKYIE EVLGGPSLHP QGALSLMILE DGPLFIADTH
VRALPTPEQL AETVISAARH VRRFGVTPNI ALCAQSNFGS QTQGSGARLR DAIAILDRMP
RDFCYEGEMN IDTALDPELR ARLMPSNRMS GAANVLIFAH ADAASGVRNI LKMKGGGLEV
GPILMGMGNK AHIVTPAITA RGLLNMAAIA GTPVSAYG
//
