ID A0A0J5S4I4_9PAST Unreviewed; 777 AA.
AC A0A0J5S4I4;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=LPS-assembly protein LptD {ECO:0000256|HAMAP-Rule:MF_01411};
DE Flags: Precursor;
GN Name=lptD {ECO:0000256|HAMAP-Rule:MF_01411};
GN ORFNames=RO21_05060 {ECO:0000313|EMBL:KMK51717.1};
OS Muribacter muris.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Muribacter.
OX NCBI_TaxID=67855 {ECO:0000313|EMBL:KMK51717.1, ECO:0000313|Proteomes:UP000036270};
RN [1] {ECO:0000313|EMBL:KMK51717.1, ECO:0000313|Proteomes:UP000036270}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ackerman80-443D {ECO:0000313|EMBL:KMK51717.1,
RC ECO:0000313|Proteomes:UP000036270};
RA Christensen H., Nicklas W., Bisgaard M.;
RT "Reclassification of Actinobacillus muris as Muribacter muris.";
RL Submitted (DEC-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Together with LptE, is involved in the assembly of
CC lipopolysaccharide (LPS) at the surface of the outer membrane.
CC {ECO:0000256|HAMAP-Rule:MF_01411}.
CC -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC complex. Interacts with LptE and LptA. {ECO:0000256|HAMAP-
CC Rule:MF_01411}.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000256|HAMAP-
CC Rule:MF_01411}.
CC -!- SIMILARITY: Belongs to the LptD family. {ECO:0000256|HAMAP-
CC Rule:MF_01411}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|HAMAP-Rule:MF_01411}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KMK51717.1}.
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DR EMBL; JWIZ01000024; KMK51717.1; -; Genomic_DNA.
DR RefSeq; WP_047976706.1; NZ_JWIZ01000024.1.
DR AlphaFoldDB; A0A0J5S4I4; -.
DR STRING; 67855.RO21_05060; -.
DR PATRIC; fig|67855.3.peg.877; -.
DR Proteomes; UP000036270; Unassembled WGS sequence.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR GO; GO:0015920; P:lipopolysaccharide transport; IEA:InterPro.
DR GO; GO:0010033; P:response to organic substance; IEA:InterPro.
DR Gene3D; 2.60.450.10; Lipopolysaccharide (LPS) transport protein A like domain; 1.
DR HAMAP; MF_01411; LPS_assembly_LptD; 1.
DR InterPro; IPR020889; LipoPS_assembly_LptD.
DR InterPro; IPR007543; LptD_C.
DR InterPro; IPR005653; OstA-like_N.
DR PANTHER; PTHR30189; LPS-ASSEMBLY PROTEIN; 1.
DR PANTHER; PTHR30189:SF1; LPS-ASSEMBLY PROTEIN LPTD; 1.
DR Pfam; PF04453; LptD; 1.
DR Pfam; PF03968; LptD_N; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Cell outer membrane {ECO:0000256|ARBA:ARBA00023237, ECO:0000256|HAMAP-
KW Rule:MF_01411};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_01411};
KW Reference proteome {ECO:0000313|Proteomes:UP000036270};
KW Signal {ECO:0000256|HAMAP-Rule:MF_01411}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01411"
FT CHAIN 23..777
FT /note="LPS-assembly protein LptD"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01411"
FT /id="PRO_5008989818"
FT DOMAIN 52..186
FT /note="Organic solvent tolerance-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF03968"
FT DOMAIN 297..682
FT /note="LptD C-terminal"
FT /evidence="ECO:0000259|Pfam:PF04453"
SQ SEQUENCE 777 AA; 88893 MW; 91827CBC74A243B6 CRC64;
MKHYRYSLLS VAIITACYSQ YAAADLRHQC LAGVPHFEGE VLTGDQTQMP VYIEADNALI
NQPTDATYTG DVSIKQGNRT VWADQVRVEQ NGGQARTAYL NGRFDYRDNL IRATGQNAQI
DLTGNQATLG NADYQLVGRQ GRGTAESVSA NEQTRILKNA SFTACLPNDN AWSIDAGEMI
QHVKEEYAEL WHARFRVMGV PVFYSPYLQF PIGDRRRSGL LIPNAGRSSR DGYYYSQPIY
WNIAPNMDAT ITPTYYTRRG WQISPEFRYL TAFGEGKMAG EYVKRDRLPS WTEKDRSRHL
FFWQHNINFL SDWRFSVDYT HVSDKRYFSD FDSVYGNSTD GYATQNFKLG YFQPHYNIAI
SGKRFQTFDD SGSKPYRVLP KVELNYYKND LVKHGDFSLY AQSAYFANDS KEMPTAWRFH
LQPALNFPLA NRYASLNLET KLYATYYLQK KGGAENAEAI ERSVTRVLPQ LKLDLKTVLS
AKQNVFSGFS QTFEPRVQYL YRPYKNQANI GSQRQSSLGL GYDSALLQQD YYALFNDRRY
SGLDRIASAN QITAGGTTRF FSNETGEEVF NFSAGQIYYL SPSKIDSTSI NSTAKRSSSW
ALESNWKFHP KWNWHGSYQY DTRLNETSLA NIALQYKPKA NNVVQLNYRY ASKNYIDQNL
SSNRYGQDIK QVGAVIGWEL TDSVSMMASH YRDIALKKPV ESQLGLTYNT CCWSATFYAA
RKLTATPEGK PDTLNDFYYD NRFGLNFELR FGSGYNSGVS RMLKRGMIPY TEAFNIN
//
