ID A0A0J6FRB1_9BACI Unreviewed; 464 AA.
AC A0A0J6FRB1;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=L-cystine uptake protein TcyP {ECO:0000256|ARBA:ARBA00022031};
DE AltName: Full=Transporter of cystine TcyP {ECO:0000256|ARBA:ARBA00031293};
GN ORFNames=AB986_13220 {ECO:0000313|EMBL:KMM36872.1};
OS Alkalihalobacillus macyae.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Alkalihalobacillus.
OX NCBI_TaxID=157733 {ECO:0000313|EMBL:KMM36872.1, ECO:0000313|Proteomes:UP000035996};
RN [1] {ECO:0000313|EMBL:KMM36872.1, ECO:0000313|Proteomes:UP000035996}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16346 {ECO:0000313|EMBL:KMM36872.1,
RC ECO:0000313|Proteomes:UP000035996};
RA Liu B., Wang J., Zhu Y., Liu G., Chen Q., Zheng C., Che J., Ge C., Shi H.,
RA Pan Z., Liu X.;
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the dicarboxylate/amino acid:cation symporter
CC (DAACS) (TC 2.A.23) family. {ECO:0000256|ARBA:ARBA00006148}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KMM36872.1}.
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DR EMBL; LELK01000004; KMM36872.1; -; Genomic_DNA.
DR RefSeq; WP_048311585.1; NZ_LELK01000004.1.
DR AlphaFoldDB; A0A0J6FRB1; -.
DR STRING; 157733.AB986_13220; -.
DR PATRIC; fig|157733.3.peg.689; -.
DR OrthoDB; 7778689at2; -.
DR Proteomes; UP000035996; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015293; F:symporter activity; IEA:InterPro.
DR Gene3D; 1.10.3860.10; Sodium:dicarboxylate symporter; 1.
DR InterPro; IPR001991; Na-dicarboxylate_symporter.
DR InterPro; IPR036458; Na:dicarbo_symporter_sf.
DR PANTHER; PTHR42865:SF5; L-CYSTINE TRANSPORTER TCYP; 1.
DR PANTHER; PTHR42865; PROTON/GLUTAMATE-ASPARTATE SYMPORTER; 1.
DR Pfam; PF00375; SDF; 1.
DR PRINTS; PR00173; EDTRNSPORT.
DR SUPFAM; SSF118215; Proton glutamate symport protein; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000035996};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..22
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 34..52
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 72..96
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 108..131
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 185..204
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 225..245
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 265..284
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 337..359
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 371..389
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 464 AA; 48644 MW; 1317819FA0F53D06 CRC64;
MNTFLVILNI AILLVLIGVL IKMQQKHVSF SKRVFAGLGF GVTLGVYLQV VFGASSDIVS
QTSDWYSIVG SGYVRLLMMI VIPLVMVSII QSITNLEKTS ELGKMSGWII GILVSTAMVA
AIVGVGSSLV FDLNAEQIEA GQAEQDRGSY LEETLGSVQD MSTPDKILAF IPANPFEDMT
GARPTSTIAV VIFSAIVGIA ALGVRRKNPE QAAVFTKGVN AVYAIVMRIV TLVLRLTPFG
IMGLMATTVA QTNVGGILEL GKFVLASYLA LLVMFIIHLL LIATGGLNPL TYLKKVLPVL
TFAFTSRSSA GTIPLNISAQ KNSLGVDEGT ANMSASFGAT IGQNGCAGIY PAMLAVMIAP
TVGIDPLSPS FLIQLVLIVG ISSFGVAGVG GGATFAALIV LSSMNLPVYL AGLLISVEPL
IDMGRTALNV NGAMTSGTLT SRILGKLNHD KFNDSHAVEK DIAV
//
