ID A0A0J6HLG7_9BACI Unreviewed; 790 AA.
AC A0A0J6HLG7;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=ATP-dependent RecD-like DNA helicase {ECO:0000256|HAMAP-Rule:MF_01488};
DE EC=3.6.4.12 {ECO:0000256|HAMAP-Rule:MF_01488};
GN Name=recD2 {ECO:0000256|HAMAP-Rule:MF_01488};
GN ORFNames=AB447_212685 {ECO:0000313|EMBL:KRT95439.1}, COP00_08175
GN {ECO:0000313|EMBL:ATH95459.1};
OS Bacillus glycinifermentans.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=1664069 {ECO:0000313|EMBL:KRT95439.1, ECO:0000313|Proteomes:UP000036168};
RN [1] {ECO:0000313|EMBL:KRT95439.1, ECO:0000313|Proteomes:UP000036168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GO-13 {ECO:0000313|EMBL:KRT95439.1,
RC ECO:0000313|Proteomes:UP000036168};
RX PubMed=26297378; DOI=10.1099/ijsem.0.000462;
RA Kim S.J., Dunlap C.A., Kwon S.W., Rooney A.P.;
RT "Bacillus glycinifermentans sp. nov., isolated from fermented soybean
RT paste.";
RL Int. J. Syst. Evol. Microbiol. 65:3586-3590(2015).
RN [2] {ECO:0000313|EMBL:KRT95439.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=GO-13 {ECO:0000313|EMBL:KRT95439.1};
RA Gilbert D.G.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ATH95459.1, ECO:0000313|Proteomes:UP000218414}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KBN06P03352 {ECO:0000313|EMBL:ATH95459.1,
RC ECO:0000313|Proteomes:UP000218414};
RA Yu W.-S., Do H.-N., Cheong H.-M., Hwang K.-J.;
RT "Whole genome sequencing of Bacillus glycinfermentans NCCP 15922.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase.
CC Has no activity on blunt DNA or DNA with 3'-overhangs, requires at
CC least 10 bases of 5'-ssDNA for helicase activity. {ECO:0000256|HAMAP-
CC Rule:MF_01488}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|HAMAP-Rule:MF_01488};
CC -!- SIMILARITY: Belongs to the RecD family. RecD-like subfamily.
CC {ECO:0000256|HAMAP-Rule:MF_01488}.
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DR EMBL; CP023481; ATH95459.1; -; Genomic_DNA.
DR EMBL; LECW02000004; KRT95439.1; -; Genomic_DNA.
DR RefSeq; WP_048406433.1; NZ_LECW02000004.1.
DR AlphaFoldDB; A0A0J6HLG7; -.
DR STRING; 1664069.BGLY_3199; -.
DR PATRIC; fig|1664069.3.peg.2561; -.
DR OrthoDB; 9803432at2; -.
DR Proteomes; UP000036168; Unassembled WGS sequence.
DR Proteomes; UP000218414; Chromosome.
DR GO; GO:0043139; F:5'-3' DNA helicase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd17933; DEXSc_RecD-like; 1.
DR CDD; cd18809; SF1_C_RecD; 1.
DR Gene3D; 1.10.10.2220; -; 1.
DR Gene3D; 2.30.30.940; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR HAMAP; MF_01488; RecD_like; 1.
DR InterPro; IPR006345; DNA_helicase_RecD-like.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR029493; RecD-like_HHH.
DR InterPro; IPR041451; RecD-like_SH13.
DR InterPro; IPR027785; UvrD-like_helicase_C.
DR NCBIfam; TIGR01448; recD_rel; 1.
DR PANTHER; PTHR43788; DNA2/NAM7 HELICASE FAMILY MEMBER; 1.
DR PANTHER; PTHR43788:SF6; RECBCD ENZYME SUBUNIT RECD; 1.
DR Pfam; PF13245; AAA_19; 1.
DR Pfam; PF14490; HHH_4; 1.
DR Pfam; PF18335; SH3_13; 1.
DR Pfam; PF13538; UvrD_C_2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|HAMAP-
KW Rule:MF_01488}; DNA-binding {ECO:0000256|HAMAP-Rule:MF_01488};
KW Helicase {ECO:0000256|HAMAP-Rule:MF_01488, ECO:0000313|EMBL:ATH95459.1};
KW Hydrolase {ECO:0000256|HAMAP-Rule:MF_01488};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|HAMAP-
KW Rule:MF_01488}.
FT DOMAIN 151..241
FT /note="RecD helicase-like helix-hairpin-helix"
FT /evidence="ECO:0000259|Pfam:PF14490"
FT DOMAIN 586..654
FT /note="RecD-like DNA helicase SH3"
FT /evidence="ECO:0000259|Pfam:PF18335"
FT DOMAIN 673..721
FT /note="UvrD-like helicase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13538"
FT BINDING 362..366
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01488"
SQ SEQUENCE 790 AA; 88912 MW; C52E91DC2686B21D CRC64;
MQMDEASFLK GTVTTVIYHN ETNLYTVLKV KVQETSESFD EKTVSVTGYF PAIFEDETYT
FYGKKASHPK FGLQFQTDHF KKEVPTTKEG VIQYLSSDLF EGIGKKTAEE IVNKLGEGAI
NRILGDASVL YDVPKLSKKK ADKLAAALQQ HQGLEQIMIS LSEFGFGPQL SMKIYQAYES
ETLDKIRENP YQLVKDVEGI GFVKADELGG RMGISGRHPE RVKAAILFTI EAACLQEGHT
YIETKQLIIE TQKLLNQSSG EEKVTEMDVA DSIISLGEQK ELFIEDDRCY YPSLYYAEQS
FAKRVLTIAE QTEYDDQFPE SEFLLALGEL EERMQVQYAP SQKEAIQKAL MSPMLLLTGG
PGTGKTTVIR GIVELYSELH GLSLNPADYK KDEAFPFVLA APTGRAAKRM SESTGLPAVT
IHRLLGWNGS EGFTHDEDNP IEGRLVIIDE TSMLDIWLAN QLFKAIPNRI QVIMVGDEDQ
LPSVGPGQVL RDLLASNVIA SVRLTDIYRQ AEGSSIVELA HDMKKGRLPQ NLTAPTKDRS
FIRCRQQQMK EVVEKVVQNA LQKGYSARDI QVLAPMYRGP AGINELNALL QNILNPPKQK
GRELKYGDVV YRTGDKVLQL VNQPEHNVFN GDMGEIVSIF YAKENTEKED MAVVSFDGNE
ITFTKKDFNQ FTHAYCCSIH KSQGSEFPIV ILPVVKSYYR MLRRNLLYTA ITRSKKFLIL
CGEEEALQWG IKNKDSSERQ TSLKRRLQQA AHEEDEELAA LQKELPFSVY DANIGMEGIT
PFDFMEKEAE
//
