ID   A0A0J6XXU6_COCIT        Unreviewed;       604 AA.
AC   A0A0J6XXU6;
DT   14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2015, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   SubName: Full=Retrograde regulation protein 2 {ECO:0000313|EMBL:KMP01046.1};
GN   ORFNames=CIRG_01186 {ECO:0000313|EMBL:KMP01046.1};
OS   Coccidioides immitis RMSCC 2394.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX   NCBI_TaxID=404692 {ECO:0000313|EMBL:KMP01046.1, ECO:0000313|Proteomes:UP000054565};
RN   [1] {ECO:0000313|Proteomes:UP000054565}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RMSCC 2394 {ECO:0000313|Proteomes:UP000054565};
RX   PubMed=20516208; DOI=10.1101/gr.103911.109;
RA   Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA   Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA   Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA   FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA   Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA   Taylor J.W., Rounsley S.D.;
RT   "Population genomic sequencing of Coccidioides fungi reveals recent
RT   hybridization and transposon control.";
RL   Genome Res. 20:938-946(2010).
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DR   EMBL; DS028093; KMP01046.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0J6XXU6; -.
DR   STRING; 404692.A0A0J6XXU6; -.
DR   Proteomes; UP000054565; Unassembled WGS sequence.
DR   CDD; cd00012; NBD_sugar-kinase_HSP70_actin; 1.
DR   Gene3D; 3.30.420.40; -; 1.
DR   Gene3D; 3.30.420.150; Exopolyphosphatase. Domain 2; 1.
DR   Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR003695; Ppx_GppA_N.
DR   PANTHER; PTHR30005; EXOPOLYPHOSPHATASE; 1.
DR   PANTHER; PTHR30005:SF0; RETROGRADE REGULATION PROTEIN 2; 1.
DR   Pfam; PF02541; Ppx-GppA; 1.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 2.
PE   4: Predicted;
FT   DOMAIN          35..334
FT                   /note="Ppx/GppA phosphatase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02541"
SQ   SEQUENCE   604 AA;  66322 MW;  536B19A4749E988F CRC64;
     MAVQENQYLH ALVDMGSNGI RFSISDLSPL TSRILPTVFQ DRTGISLYDA QFRPGSNTRQ
     PISLSVQEDV VRRLVRFRET CKDFGVPEGN ITVLATEATR TAINSREFLS AIKESTGWDV
     QLLSKEEEGI LGAFGIASSL EAVEGLVMDL GGGSTQITWV IAKDGSVLTS PKGSISLPYG
     AAAVTKRLEK RSERQNLENE MIPKFRDAYS ELCVPKELLE HAAKRGGFDL FLSGGGFRGW
     GYLHMNRSKI NPYPIPIING FRVDCSEFCD TSGIMSSAAM EGSKIFGVSD RRASQVPAVA
     CLVKSLTKAI PNIKTIQFCQ GGVREGYLFK TLPEEIRLKS PLVVATAPYS TQSAFELSSL
     LLRALPCGVP ENTDASVPLS FTETMIVALA NIMFAHSSIS RESRAAVALH STINGLLASA
     HGISHADRAL LALLLYERWR GDLSPSDQSL LRRLRQITSR EEVWWCQYLG RVAALVCDIY
     PSGIIRDKIP RVDFVAGWAK GKKGKTHVRL EITLPNNSPG VDLSWLMGAK QSVEKAGKKK
     NWVRAVERIG EFEDWGLKID VSLNEGRMQV DGHLIILQNV SERNVNTGNP VGPCHGKEKQ
     GYPK
//