ID A0A0J6Y239_COCIT Unreviewed; 522 AA.
AC A0A0J6Y239;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 13-SEP-2023, entry version 21.
DE RecName: Full=Nuclear polyadenylated RNA-binding protein Nab2 {ECO:0008006|Google:ProtNLM};
GN ORFNames=CIRG_01174 {ECO:0000313|EMBL:KMP01034.1};
OS Coccidioides immitis RMSCC 2394.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=404692 {ECO:0000313|EMBL:KMP01034.1, ECO:0000313|Proteomes:UP000054565};
RN [1] {ECO:0000313|Proteomes:UP000054565}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RMSCC 2394 {ECO:0000313|Proteomes:UP000054565};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; DS028093; KMP01034.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0J6Y239; -.
DR STRING; 404692.A0A0J6Y239; -.
DR Proteomes; UP000054565; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008143; F:poly(A) binding; IEA:InterPro.
DR GO; GO:1900364; P:negative regulation of mRNA polyadenylation; IEA:InterPro.
DR GO; GO:0043488; P:regulation of mRNA stability; IEA:InterPro.
DR Gene3D; 4.10.1000.30; -; 1.
DR Gene3D; 4.10.1000.40; -; 1.
DR Gene3D; 1.10.340.40; Nuclear abundant poly(A) RNA-bind protein 2, N-terminal domain; 1.
DR InterPro; IPR040366; Nab2/ZC3H14.
DR InterPro; IPR043094; Nab2/ZC3H14_N_sf.
DR PANTHER; PTHR14738; ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 14; 1.
DR PANTHER; PTHR14738:SF29; ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 14; 1.
DR Pfam; PF14608; zf-CCCH_2; 4.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT REGION 132..158
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 190..215
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 300..349
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 489..522
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 313..349
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 489..508
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 522 AA; 57272 MW; A7264B70BAA6205C CRC64;
MAISVELNTP LAQALNEVIQ PKLVEVGWST GGGDDSALAE YVILMLVNGK TQEQIASELA
NDLLGLGPDD TEAVDFSRWL FEQVELLNKR LNGELAEPEP ENAAQAIPSF TEGSDDAAAP
ASAPLKFDAE MTDSPLQPRE GGLPSGPRNM RNPKQNGRGR LLGQITRAMD RSSESVLHRV
RNQSGAERIN MHREPPRGPR AFQARGGRSG GGRQAGGMGM NMGMGAMGMG NNPMQNMPPG
SNMMTPQQQM QMMALFEEQA RMMAQFMPGF VPPAINPAFQ TAQGLQNQGR SLFERAEHHK
DRNPHFQRHH QNGRQHNQGT NMDVDGGPKE STDTQMEEAP QSESQDRGTE GVCRYNLRCT
NKDCPYAHQS PAAPEGTTVD VSDVCPFGAA CKNRKCVARH PSPAQKAMHQ SEELCKYFPH
CQNPHCQFKH PSMPLCRNGA DCSVPGCKFT HQQIPCRYKP CLNPTCPFKH SEGQKGVFSD
KVWTAERKDA PHVSERKFVS DEAGEEELIK PPPSSSEAEI VT
//
