ID   A0A0J6YBB7_COCIT        Unreviewed;      1090 AA.
AC   A0A0J6YBB7;
DT   14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2015, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   RecName: Full=Nuclear pore complex protein {ECO:0000256|RuleBase:RU365072};
GN   ORFNames=CIRG_03784 {ECO:0000313|EMBL:KMP04093.1};
OS   Coccidioides immitis RMSCC 2394.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX   NCBI_TaxID=404692 {ECO:0000313|EMBL:KMP04093.1, ECO:0000313|Proteomes:UP000054565};
RN   [1] {ECO:0000313|Proteomes:UP000054565}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RMSCC 2394 {ECO:0000313|Proteomes:UP000054565};
RX   PubMed=20516208; DOI=10.1101/gr.103911.109;
RA   Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA   Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA   Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA   FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA   Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA   Taylor J.W., Rounsley S.D.;
RT   "Population genomic sequencing of Coccidioides fungi reveals recent
RT   hybridization and transposon control.";
RL   Genome Res. 20:938-946(2010).
CC   -!- FUNCTION: Functions as a component of the nuclear pore complex (NPC).
CC       {ECO:0000256|RuleBase:RU365072}.
CC   -!- SUBUNIT: Part of the nuclear pore complex (NPC).
CC       {ECO:0000256|RuleBase:RU365072}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nuclear pore complex
CC       {ECO:0000256|RuleBase:RU365072}. Nucleus membrane
CC       {ECO:0000256|RuleBase:RU365072}.
CC   -!- SIMILARITY: Belongs to the nucleoporin Nup84/Nup107 family.
CC       {ECO:0000256|RuleBase:RU365072}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; DS028094; KMP04093.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0J6YBB7; -.
DR   STRING; 404692.A0A0J6YBB7; -.
DR   Proteomes; UP000054565; Unassembled WGS sequence.
DR   GO; GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005643; C:nuclear pore; IEA:UniProtKB-SubCell.
DR   GO; GO:0017056; F:structural constituent of nuclear pore; IEA:UniProtKB-UniRule.
DR   GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.3450.20; -; 1.
DR   Gene3D; 1.20.190.50; -; 1.
DR   InterPro; IPR007252; Nup84/Nup107.
DR   PANTHER; PTHR13003:SF2; NUCLEAR PORE COMPLEX PROTEIN NUP107; 1.
DR   PANTHER; PTHR13003; NUP107-RELATED; 1.
DR   Pfam; PF04121; Nup84_Nup100; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|RuleBase:RU365072};
KW   mRNA transport {ECO:0000256|ARBA:ARBA00022816};
KW   Nuclear pore complex {ECO:0000256|RuleBase:RU365072};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU365072};
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW   Translocation {ECO:0000256|ARBA:ARBA00023010,
KW   ECO:0000256|RuleBase:RU365072};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU365072}.
FT   REGION          1..150
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          211..239
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          857..877
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        30..95
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        213..239
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1090 AA;  124689 MW;  38018513DF306B50 CRC64;
     MAAFSHSLRD GRDSVLSNGS SMIPHDAEII EIDDDSDGEV QDKEVPMNED DEEISEGDED
     DEEDEMEEEE DYDEDEDHEM RFENGEEDEA EEEESVRDYH ENGEEAEELP SEYGGTNGTH
     SIEEPYPNWK ARIEGHTPRS PAFTPSNLLS SDIKQTLHPL QDMAERVLKQ IESFAHNLDQ
     FRRQSPTPHD PRAFREACKL VKTYQSIAEN NARDLSKADR SQKPKRSTQE EKESENVADE
     VEEQIARWQR EAETWDLLSQ LLLIADPETR ERAEQCQETA LQSLHRYSSD QEVWEKFLET
     DLFARECVIV LQWLEKTARS AKGRDSVVSE LDKDTDRDQG LWAHGWLYTK ETIKGAKRLR
     SWPQPLDPED SRVTSSLLGS ERQAPLITQL DPDAIIRQGL GLQKQDQVHE QAAWLTCWKM
     LRSGRSWSEI RAWSQERLES WRAISVFGAS LHPNSKSTSL PDTGLSRMMS CRSQQSWKSA
     CSVLASDPHV DRYERAVYAL LCGETKPAYA VCQSWDDFLY VFYNHMVLSR YSDFCKQFLR
     KLGLPSNTKV LVNIEPANHD GIRYFLSNIR KDERFAEESK NFYRQIQAAI LSQNYDYFFY
     NHAIAKSKYV EHINGPSLLP LRPPPGMTQD PLLTAPDDES SLRIIAHLYL LLSFVGIFRV
     ESHLLDQYGL NVIKYVEVLR EKDKMDLIPL YASLLPETMG QATLGIVLIN VLGEGERQVL
     LQRMRAFGIN VSGVLSCQWQ WALAGTDIDV KKPIKIAGKF VTEQKPGSIS ALNKDIIGRD
     VPLRHERLIR CMEWYSFVGT EWPTLCVNIA YLYKRFLRRT QLATARELWK RIQFSQIPVP
     PEFNLIALKV DANADSDINQ SADNRPASPV KAGRSKSPLK SAAYHRQHLS SMSSGKTVAE
     QLCIHARTVE DLELLISTLD AMERWGNLSD EYLELSNPER KREFQQMLQQ AIDDVTENVN
     PLCQDWLCRP LNEEEAAEFD LIRTAYLPEI ILMYHNSLYL AGCTIGREIL AQCMSLSIAI
     AGSQTLTECF VSAGRMRELA RALAMSSMAI MTLKDPKLKK KLPRNATLDI WKIKPIEEDA
     VGLTQHWKKG
//