ID A0A0J6YGM1_COCIT Unreviewed; 1433 AA.
AC A0A0J6YGM1;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Eukaryotic initiation factor 4F subunit p130 {ECO:0000313|EMBL:KMP06224.1};
GN ORFNames=CIRG_05904 {ECO:0000313|EMBL:KMP06224.1};
OS Coccidioides immitis RMSCC 2394.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=404692 {ECO:0000313|EMBL:KMP06224.1, ECO:0000313|Proteomes:UP000054565};
RN [1] {ECO:0000313|Proteomes:UP000054565}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RMSCC 2394 {ECO:0000313|Proteomes:UP000054565};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
CC -!- SIMILARITY: Belongs to the eukaryotic initiation factor 4G family.
CC {ECO:0000256|ARBA:ARBA00005775}.
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DR EMBL; DS028096; KMP06224.1; -; Genomic_DNA.
DR STRING; 404692.A0A0J6YGM1; -.
DR Proteomes; UP000054565; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.180; -; 1.
DR Gene3D; 1.20.970.30; eIF4G, eIF4E-binding domain; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR022745; eIF4G1_eIF4E-bd.
DR InterPro; IPR036211; eIF4G_eIF4E-bd_sf.
DR InterPro; IPR045208; IF4G.
DR InterPro; IPR003890; MIF4G-like_typ-3.
DR PANTHER; PTHR23253; EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA; 1.
DR PANTHER; PTHR23253:SF9; EUKARYOTIC TRANSLATION INITIATION FACTOR 4G1, ISOFORM B-RELATED; 1.
DR Pfam; PF12152; eIF_4G1; 1.
DR Pfam; PF02854; MIF4G; 1.
DR SMART; SM00543; MIF4G; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF101489; Eukaryotic initiation factor 4f subunit eIF4g, eIF4e-binding domain; 1.
PE 3: Inferred from homology;
KW Initiation factor {ECO:0000313|EMBL:KMP06224.1};
KW Protein biosynthesis {ECO:0000313|EMBL:KMP06224.1}.
FT DOMAIN 1000..1240
FT /note="MIF4G"
FT /evidence="ECO:0000259|SMART:SM00543"
FT REGION 1..340
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 390..745
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 893..997
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1257..1433
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..31
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 42..86
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 131..196
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 206..224
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 269..291
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 307..331
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 397..468
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 494..526
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 527..563
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 565..582
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 586..612
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 619..697
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 707..722
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 913..931
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1257..1275
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1321..1347
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1381..1427
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1433 AA; 152800 MW; 3B542EDC150CEA91 CRC64;
MTSNPPTSNL QPQTQSTSQG QSSSGKTSPL TPVPVPSAPR SYASATKKSF SQVAAGDSAN
KPVSTTAQGS QHGKSPSTSQ VNGKPAMQNP PVPGAGGPTI VNGNPAANDH ARKPSMTISA
AGATGFISNG GPVSGRPNNI RFGFGDSQSS PSMGAAVLAN QQSSLGVSPV NNRITSPDSS
PSPIPQTLSG GRQPPSHIQG PGNMHFGNFS GEQNDLNRNL RPGSQPPLPN NPQPNHARRE
SAQSAHGDMG GHNIPSGPTR GGYHAQGGRG RNYNQSQVPY NSPGSTYRSH HGQRSGHFHS
QGRPMGPFQG SPHQSARSPA MASANPATPP TTHVPMANPP MQAQHFGYAQ HMGHQQGYAP
PASYETGGYY YPTQYPYQMH MPHLVSGPAR QPYMGSQPPF MPNQYAGSAN PPAQTASLQT
STPQAPAAER PGSSLGHGQQ SSVSMTQAPS HTPNRSTSSP SPNPQFVLPK RSSGVVIKNP
NSGDVVAFDR QGNSPARATP SPAKLGTTPS STPPPRTASR GDQEQAESKV QTQEEKIQSF
HEKVRMAAEQ AAEEQKALEL KKSQESLQPE PTKPSTDATD TTEPVAPAKE AEKPEKEPEL
KEEPKPAEPA EEEIDFDAIE RELAAKEAEE LAREKAYQEK KQREKEEAAR KAKEEAEAYE
ANMKKAEAEA EAAEEERLRK LAAAESEASK KEKADAFAAL TNKAATPAES PAVQTPAESG
AATPVSDVSM GPPKNIPGGK REKPAALKLE TNKTVEPPQP SAALKSLQTA RFLEDPSKIS
YPPSIVSPSP AFNVNAPSDR KFKYNKEFLL QFQNVFKEKP SLDWDTKVRE TVGDGSTDSR
SAMRTPVVNR TPSRTGVGGG AFDRMGMFQG AGRTQTMPSG GQDRFPISGM RGTALGGNFG
QFGRGPGGLT MGPPMSRTSS SSAQQIPGSP RSGSHRGGRS ASKAHKSAKK EEETNKTMPL
TAGQKIEPLA PSSGGWKPRS IGRAQNLVGP DGHLPPDVVQ GKVKSNLNKM TPEKFDKISD
QILAIVAQSK DESDGRTLRQ VIQLTFEKAT DEAHWAPLYA KFCMRMLESM SPEIQDENIK
DKHGNVVCGG SLFRKYLLNR CQEEFERGWK VNLPPKPEGT TDEAAMLSDE YYIAAAAKRR
GLGLVKFIGE LFKLSMLSDR IMHECVKKLV DYEGVPEEAE IESLTNLLRT IGATLDRSSD
KGHMMMNAYF ERIDKMVQTP GLPSRLKFML MDIIDLRKAN WVSKDADKGP KTIQEIREQA
ARAQQEQEME RKRQQASRGS GGIGLGRGDA RNFSGGYGNQ PPLDYASSKV GSDDLRRLKA
PRTTNQPTSF GPSSLLGSRS SSGRRTIGPG GNLVRGGEDS GASSRTGTPP GGKKDDKESA
STNAFSALAS LDTGDSLATS PPSNPTSPQL TKSRPAVAQQ SHAQGKDDSA GAS
//
