ID   A0A0J6YIC6_COCIT        Unreviewed;       740 AA.
AC   A0A0J6YIC6;
DT   14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2015, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=Protein CASP {ECO:0000256|ARBA:ARBA00018691};
GN   ORFNames=CIRG_07056 {ECO:0000313|EMBL:KMP07375.1};
OS   Coccidioides immitis RMSCC 2394.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX   NCBI_TaxID=404692 {ECO:0000313|EMBL:KMP07375.1, ECO:0000313|Proteomes:UP000054565};
RN   [1] {ECO:0000313|Proteomes:UP000054565}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RMSCC 2394 {ECO:0000313|Proteomes:UP000054565};
RX   PubMed=20516208; DOI=10.1101/gr.103911.109;
RA   Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA   Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA   Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA   FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA   Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA   Taylor J.W., Rounsley S.D.;
RT   "Population genomic sequencing of Coccidioides fungi reveals recent
RT   hybridization and transposon control.";
RL   Genome Res. 20:938-946(2010).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004211}; Single-
CC       pass type IV membrane protein {ECO:0000256|ARBA:ARBA00004211}.
CC   -!- SIMILARITY: Belongs to the CASP family.
CC       {ECO:0000256|ARBA:ARBA00006415}.
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DR   EMBL; DS028097; KMP07375.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0J6YIC6; -.
DR   STRING; 404692.A0A0J6YIC6; -.
DR   Proteomes; UP000054565; Unassembled WGS sequence.
DR   GO; GO:0000139; C:Golgi membrane; IEA:InterPro.
DR   GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; IEA:InterPro.
DR   InterPro; IPR012955; CASP_C.
DR   PANTHER; PTHR14043; CCAAT DISPLACEMENT PROTEIN-RELATED; 1.
DR   PANTHER; PTHR14043:SF2; HOMEOBOX PROTEIN CUT; 1.
DR   Pfam; PF08172; CASP_C; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        680..698
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          442..701
FT                   /note="CASP C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08172"
FT   REGION          1..27
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          152..233
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          258..292
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          333..360
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          419..474
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          536..584
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   740 AA;  82707 MW;  333A1771F14A339F CRC64;
     MDTLAASESA GDKPNVDVQH AEKPQEETKF QRAISAWRSI DLANLVSKLD TTASDIVAHQ
     RDSLVQRKDL AQKTKDFRRL DDASKLAEYK GLLKSYQAFI DLLTTHGKAS SSAFLQLYSA
     FSEAPDPYPL LEASIDSLVL SEDTVPKLTA EKETLQKSVS QLTLQLEESE KKLEEERSLR
     RKLEQEQEKK IQEVEASWTA VLSEKTSNWE AKEKSYEEKA ENHERLLKEI KASYEVSQRL
     DSQDDGDTQR SAATAAELEI VAADLEKTSL RLAEVEARNE QLRLDLAQAV SHPHSEPKHR
     PVEEEPEYLR LQSENSSLLR KLESARFDKD VEKNASEAKL RQVERRNARV TTERDELRTK
     LEKVADYDDI RRELEIIKSI EFSTGNDDTA DLNDGAIEDA TVSTNSKENN LEQLLLARNK
     KLSNELTLLR VSHRDLESQL ESLREELSKT NADLERSRNL TANLENDLLQ VQKETTQSSA
     MSIAGTYTSR YPYSARRGRA SPTSSIISGF DHGVAPTNSL EAIRAGEAMG GGSGILPMVQ
     AQRDRFKQKN AELEDELSKT YATVKTLRQE IASLQKDNLN LYEKTRYIST YNRGGQVATS
     SSSSAFASQP HQTSAHVASD GPFGMYLDKY HSAYEAQISP FAAFRGREST RAYKRMSLPE
     RIIFSITRMV LANRTSRNMF AAYCLALHVL VFVMLYMIST LEVGKQSATL GSMAGVAAAQ
     GGSGAGASPE GWQQEAPRID
//