ID   A0A0J6YLI5_COCIT        Unreviewed;       266 AA.
AC   A0A0J6YLI5;
DT   14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2015, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   RecName: Full=DNA polymerase epsilon subunit D {ECO:0000256|ARBA:ARBA00039775};
DE   AltName: Full=DNA polymerase II subunit D {ECO:0000256|ARBA:ARBA00042096};
GN   ORFNames=CIRG_08216 {ECO:0000313|EMBL:KMP08535.1};
OS   Coccidioides immitis RMSCC 2394.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX   NCBI_TaxID=404692 {ECO:0000313|EMBL:KMP08535.1, ECO:0000313|Proteomes:UP000054565};
RN   [1] {ECO:0000313|Proteomes:UP000054565}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RMSCC 2394 {ECO:0000313|Proteomes:UP000054565};
RX   PubMed=20516208; DOI=10.1101/gr.103911.109;
RA   Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA   Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA   Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA   FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA   Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA   Taylor J.W., Rounsley S.D.;
RT   "Population genomic sequencing of Coccidioides fungi reveals recent
RT   hybridization and transposon control.";
RL   Genome Res. 20:938-946(2010).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   EMBL; DS028098; KMP08535.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0J6YLI5; -.
DR   STRING; 404692.A0A0J6YLI5; -.
DR   Proteomes; UP000054565; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR   InterPro; IPR003958; CBFA_NFYB_domain.
DR   InterPro; IPR009072; Histone-fold.
DR   PANTHER; PTHR46172; DNA POLYMERASE EPSILON SUBUNIT 3; 1.
DR   PANTHER; PTHR46172:SF1; DNA POLYMERASE EPSILON SUBUNIT 3; 1.
DR   Pfam; PF00808; CBFD_NFYB_HMF; 1.
DR   SUPFAM; SSF47113; Histone-fold; 1.
PE   4: Predicted;
KW   DNA replication {ECO:0000256|ARBA:ARBA00022705}.
FT   DOMAIN          19..79
FT                   /note="Transcription factor CBF/NF-Y/archaeal histone"
FT                   /evidence="ECO:0000259|Pfam:PF00808"
FT   REGION          104..158
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          172..266
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        125..158
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        179..218
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        239..266
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   266 AA;  29992 MW;  5103D38D705949A3 CRC64;
     MSVLLTMAHH WNTLQDFLLP RTLTQRLAKG ALPPNTSIQK DALLAITKAA TVFVSYLSSN
     ANEETEKKTI TPQDVLSALK EIEFDSFRPQ LEQELVIYME TAVQKRQSKN EKKSQGNASA
     KEKACVNDGN KEPIIKRQKR DNEQHTPETG HHRHVKNSEV TYSLQACGIM PYNEEGGLHT
     DDTEEDDAEE EEEEEEEEEE EDDDDDDDDD GDDDDSDTQM AGVAEKQVND DGNDATEEQE
     LSEDSKSDMV RKKHFNLDSG IDSESD
//