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Database: UniProt
Entry: A0A0J7ABE6_9ACTN
LinkDB: A0A0J7ABE6_9ACTN
Original site: A0A0J7ABE6_9ACTN 
ID   A0A0J7ABE6_9ACTN        Unreviewed;       198 AA.
AC   A0A0J7ABE6;
DT   14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2015, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   SubName: Full=RNA polymerase sigma factor SigK {ECO:0000313|EMBL:KMO94561.1};
GN   ORFNames=ACS04_28550 {ECO:0000313|EMBL:KMO94561.1};
OS   Streptomyces roseus.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=66430 {ECO:0000313|EMBL:KMO94561.1, ECO:0000313|Proteomes:UP000035932};
RN   [1] {ECO:0000313|EMBL:KMO94561.1, ECO:0000313|Proteomes:UP000035932}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31245 {ECO:0000313|EMBL:KMO94561.1,
RC   ECO:0000313|Proteomes:UP000035932};
RA   Cruz-Morales P., Martinez-Guerrero C., Morales-Escalante M.A.,
RA   Yanez-Guerra L.A., Kopp J.F., Feldmann J., Ramos-Aboites H.E.,
RA   Barona-Gomez F.;
RT   "Recapitulation of the evolution of biosynthetic gene clusters reveals
RT   hidden chemical diversity on bacterial genomes.";
RL   Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the sigma-70 factor family. ECF subfamily.
CC       {ECO:0000256|ARBA:ARBA00010641}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KMO94561.1}.
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DR   EMBL; LFML01000126; KMO94561.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0J7ABE6; -.
DR   STRING; 66430.ACS04_28550; -.
DR   PATRIC; fig|66430.4.peg.1368; -.
DR   Proteomes; UP000035932; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0016987; F:sigma factor activity; IEA:InterPro.
DR   GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProt.
DR   CDD; cd06171; Sigma70_r4; 1.
DR   Gene3D; 1.10.1740.10; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR039425; RNA_pol_sigma-70-like.
DR   InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR   InterPro; IPR007627; RNA_pol_sigma70_r2.
DR   InterPro; IPR013249; RNA_pol_sigma70_r4_t2.
DR   InterPro; IPR013325; RNA_pol_sigma_r2.
DR   InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   NCBIfam; TIGR02937; sigma70-ECF; 1.
DR   PANTHER; PTHR43133:SF70; ECF RNA POLYMERASE SIGMA FACTOR SIGK; 1.
DR   PANTHER; PTHR43133; RNA POLYMERASE ECF-TYPE SIGMA FACTO; 1.
DR   Pfam; PF04542; Sigma70_r2; 1.
DR   Pfam; PF08281; Sigma70_r4_2; 1.
DR   SUPFAM; SSF88946; Sigma2 domain of RNA polymerase sigma factors; 1.
DR   SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000035932};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          39..106
FT                   /note="RNA polymerase sigma-70 region 2"
FT                   /evidence="ECO:0000259|Pfam:PF04542"
FT   DOMAIN          138..190
FT                   /note="RNA polymerase sigma factor 70 region 4 type 2"
FT                   /evidence="ECO:0000259|Pfam:PF08281"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   198 AA;  22230 MW;  29838700F031D09F CRC64;
     MNQPVPINTG RPSDDHGGSG LTDLMQKVAH GDKEAFSDLY DALAPMVFGI VVKVVRDRAQ
     SEEVSQEVMI DLWRQAARYR PEAGSVTTWA ATIAHRRAVD RVRSAQASAH REHAQAAREH
     TIAFDEVAEQ VETRLDSEQV RRCMRGLTEV QRQAVTLAYY QGLTYREVAE ALRTPLPTIK
     TRMRDGLIRL RDCMGVTT
//
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