ID A0A0J7ASN7_COCIT Unreviewed; 476 AA.
AC A0A0J7ASN7;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=CENP-T/Histone H4 histone fold domain-containing protein {ECO:0000259|Pfam:PF15511};
GN ORFNames=CIRG_00429 {ECO:0000313|EMBL:KMP00287.1};
OS Coccidioides immitis RMSCC 2394.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=404692 {ECO:0000313|EMBL:KMP00287.1, ECO:0000313|Proteomes:UP000054565};
RN [1] {ECO:0000313|Proteomes:UP000054565}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RMSCC 2394 {ECO:0000313|Proteomes:UP000054565};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the CENP-T/CNN1 family.
CC {ECO:0000256|ARBA:ARBA00010137}.
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DR EMBL; DS028093; KMP00287.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0J7ASN7; -.
DR STRING; 404692.A0A0J7ASN7; -.
DR Proteomes; UP000054565; Unassembled WGS sequence.
DR GO; GO:0000776; C:kinetochore; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0051382; P:kinetochore assembly; IEA:InterPro.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR InterPro; IPR028255; CENP-T.
DR InterPro; IPR035425; CENP-T/H4_C.
DR InterPro; IPR009072; Histone-fold.
DR PANTHER; PTHR46904; CENTROMERE PROTEIN T; 1.
DR PANTHER; PTHR46904:SF1; CENTROMERE PROTEIN T; 1.
DR Pfam; PF15511; CENP-T_C; 1.
DR SUPFAM; SSF47113; Histone-fold; 1.
PE 3: Inferred from homology;
KW Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242}.
FT DOMAIN 369..475
FT /note="CENP-T/Histone H4 histone fold"
FT /evidence="ECO:0000259|Pfam:PF15511"
FT REGION 1..92
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 133..168
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 338..373
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 53..67
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 476 AA; 52486 MW; C22EB21A49AF020E CRC64;
MSSPSGPDAL RITPRRRRGS AGAGPSPAHN TPSSILQQLA GMAGDPATPA GRSRRSLSAS
RVSLRRSSRG VSGIGISDAF AGGSHAPATP HALKAFQRRA AVYTPGRDRR KSGRVQRETP
LDILRNLGKA LAPTSEVIKS SPMTETDQET DQQESEDLDE EPDLPRPRLS LPMHEMIVPG
DGDGSPEIVP PRLSLPLDED DFTQRSIEMP RRERSTRDLA TLSRYSLAST RFSEHFGDAS
RLEYTEEGME FTAPQGDDNF VDDQIELTAE QPIFDLGGET EDLRRFDLNF SFPTPDAPQH
IENEHEDFVL DTTMPIADDV PVSSDDDFGA GDLELAVREG SPRPPLQESS PQPPQESRLD
QNKERVSKHG IPVPKLPRGI VKRLATRFAR TGNGSRTRIS KEALAALEKA TDWFFEQAND
DLSAYSKHSN RKTVDETDVI ALMKRQRQIG KGTSVFALAQ KYLPKELLQD IRLAKK
//
