ID A0A0J7IBC2_9FLAO Unreviewed; 529 AA.
AC A0A0J7IBC2;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Replicative DNA helicase {ECO:0000256|ARBA:ARBA00021957, ECO:0000256|RuleBase:RU362085};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551, ECO:0000256|RuleBase:RU362085};
GN ORFNames=ACM40_02650 {ECO:0000313|EMBL:KMQ63713.1};
OS Chryseobacterium sp. BLS98.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales; Weeksellaceae;
OC Chryseobacterium group; Chryseobacterium.
OX NCBI_TaxID=885586 {ECO:0000313|EMBL:KMQ63713.1, ECO:0000313|Proteomes:UP000036030};
RN [1] {ECO:0000313|EMBL:KMQ63713.1, ECO:0000313|Proteomes:UP000036030}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BLS98 {ECO:0000313|EMBL:KMQ63713.1,
RC ECO:0000313|Proteomes:UP000036030};
RA Pipes S.E., Miller J.R., Newman J.D.;
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Participates in initiation and elongation during chromosome
CC replication; it exhibits DNA-dependent ATPase activity.
CC {ECO:0000256|RuleBase:RU362085}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665,
CC ECO:0000256|RuleBase:RU362085};
CC -!- SIMILARITY: Belongs to the helicase family. DnaB subfamily.
CC {ECO:0000256|ARBA:ARBA00008428, ECO:0000256|RuleBase:RU362085}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KMQ63713.1}.
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DR EMBL; LFNF01000001; KMQ63713.1; -; Genomic_DNA.
DR RefSeq; WP_048501274.1; NZ_LFNF01000001.1.
DR AlphaFoldDB; A0A0J7IBC2; -.
DR STRING; 885586.ACM40_02650; -.
DR PATRIC; fig|885586.5.peg.537; -.
DR OrthoDB; 9773982at2; -.
DR Proteomes; UP000036030; Unassembled WGS sequence.
DR GO; GO:1990077; C:primosome complex; IEA:UniProtKB-UniRule.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003678; F:DNA helicase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006269; P:DNA replication, synthesis of RNA primer; IEA:UniProtKB-UniRule.
DR CDD; cd00984; DnaB_C; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036185; DNA_heli_DnaB-like_N_sf.
DR InterPro; IPR007692; DNA_helicase_DnaB.
DR InterPro; IPR007694; DNA_helicase_DnaB-like_C.
DR InterPro; IPR007693; DNA_helicase_DnaB-like_N.
DR InterPro; IPR016136; DNA_helicase_N/primase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR00665; DnaB; 1.
DR PANTHER; PTHR30153:SF2; REPLICATIVE DNA HELICASE; 1.
DR PANTHER; PTHR30153; REPLICATIVE DNA HELICASE DNAB; 1.
DR Pfam; PF00772; DnaB; 1.
DR Pfam; PF03796; DnaB_C; 1.
DR SUPFAM; SSF48024; N-terminal domain of DnaB helicase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51199; SF4_HELICASE; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU362085};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705,
KW ECO:0000256|RuleBase:RU362085};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU362085};
KW Helicase {ECO:0000256|RuleBase:RU362085, ECO:0000313|EMBL:KMQ63713.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU362085};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU362085}; Primosome {ECO:0000256|RuleBase:RU362085}.
FT DOMAIN 195..473
FT /note="SF4 helicase"
FT /evidence="ECO:0000259|PROSITE:PS51199"
FT REGION 503..529
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 529 AA; 58666 MW; 2F16A4DA6B9069D9 CRC64;
MAQKETLSSL THGNFARELS IADGKMPPNA VDFERLVIGT FLIDKKGLDH SIDLLTPEVF
YDPRHQVIFS TILKLYEGNH PVDLMTIIQE LKKEDKLSQA GGDHYIIDLT MGVSSSAHIE
YHVRVILEKY ILRSLINVSA NVIDSSYKES TDVFELLDKA EQSFFEITNG TIKKGFDTAN
SLVKQAIDTI KSLKDKEGLS GVPSGFRDID KETGGWQNSD LIIIAARPAM GKTAFLLSMA
RNIAVGHKIP MVLFSLEMAS VQLITRMIAS ETKISSEKLR KGTLDDEEWQ RLFSNVSELE
NAPLFIDETP SLSIFDFRAK CRRLVMQHGV KLIMVDYLQL MTAGGGGKGV GNREQEISMI
SRSLKAIAKE LNVPVIALSQ LSRSVEARPG KRPQLSDLRE SGAIEQDADI VSFIFRPEYY
KISVWDNDEE GQETSTENQA ELIIAKHRNG ATADVRLSFL KHFAKFGDIE AAFDGGMGGY
PSNFGSNEPS GFDKIKTTIQ PGAAFDLPDN SKLSGSSMND FDDDDDFPF
//
