ID A0A0J7IZ69_9FLAO Unreviewed; 318 AA.
AC A0A0J7IZ69;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=2-hydroxyacid dehydrogenase {ECO:0000313|EMBL:KMQ71312.1};
GN ORFNames=ACM44_07895 {ECO:0000313|EMBL:KMQ71312.1};
OS Chryseobacterium koreense CCUG 49689.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales; Weeksellaceae;
OC Chryseobacterium group; Chryseobacterium.
OX NCBI_TaxID=1304281 {ECO:0000313|EMBL:KMQ71312.1, ECO:0000313|Proteomes:UP000035900};
RN [1] {ECO:0000313|EMBL:KMQ71312.1, ECO:0000313|Proteomes:UP000035900}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCUG 49689 {ECO:0000313|EMBL:KMQ71312.1,
RC ECO:0000313|Proteomes:UP000035900};
RX PubMed=15545478; DOI=10.1099/ijs.0.02998-0;
RA Kim M.K., Im W.T., Shin Y.K., Lim J.H., Kim S.H., Lee B.C., Park M.Y.,
RA Lee K.Y., Lee S.T.;
RT "Kaistella koreensis gen. nov., sp. nov., a novel member of the
RT Chryseobacterium-Bergeyella-Riemerella branch.";
RL Int. J. Syst. Evol. Microbiol. 54:2319-2324(2004).
CC -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC dehydrogenase family. {ECO:0000256|RuleBase:RU003719}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KMQ71312.1}.
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DR EMBL; LFNG01000009; KMQ71312.1; -; Genomic_DNA.
DR RefSeq; WP_048499479.1; NZ_LFNG01000009.1.
DR AlphaFoldDB; A0A0J7IZ69; -.
DR STRING; 1304281.ACM44_07895; -.
DR PATRIC; fig|1304281.5.peg.1687; -.
DR OrthoDB; 9777288at2; -.
DR Proteomes; UP000035900; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd12179; 2-Hacid_dh_14; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43761:SF1; 2-HACID_DH DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR43761; D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G13630); 1.
DR Pfam; PF00389; 2-Hacid_dh; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|RuleBase:RU003719};
KW Reference proteome {ECO:0000313|Proteomes:UP000035900}.
FT DOMAIN 4..312
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase
FT catalytic"
FT /evidence="ECO:0000259|Pfam:PF00389"
FT DOMAIN 105..293
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
SQ SEQUENCE 318 AA; 35484 MW; 20192C74A8113582 CRC64;
MKVLLLDKNH PLITEQLSPK GFEFEEDFDS PYDEVLQKIS NYDGIIIRSR IPIDRNFLEH
ATHLKFIARV GAGLENIDVD FAKSSGIKVI SSPEGNRDSV AEHVLGMLLI LMNRLFIASD
EVKSGIWRRE ENRGDELKGK TFGIIGYGNM GKAVAKRLSG FGVNVIFHDI LPNLSDESGT
QVSLETLKNE TDILSLHTPI TPETHHLIDE EFISAMKKDF YFVNTARGKN VKTKDLVEAI
KKGKIKGAAL DVLEYEKASF ENLDAPSSPG NHENEDLKFL LNSEKVIVTP HIAGWTIQSK
EKLAQVIVDK ILAEFAVS
//
