ID   A0A0J7KAF3_LASNI        Unreviewed;       452 AA.
AC   A0A0J7KAF3;
DT   14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2015, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Sodium calcium exchanger 3 {ECO:0000313|EMBL:KMQ87403.1};
DE   Flags: Fragment;
GN   ORFNames=RF55_13322 {ECO:0000313|EMBL:KMQ87403.1};
OS   Lasius niger (Black garden ant).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC   Formicidae; Formicinae; Lasius; Lasius.
OX   NCBI_TaxID=67767 {ECO:0000313|EMBL:KMQ87403.1, ECO:0000313|Proteomes:UP000036403};
RN   [1] {ECO:0000313|EMBL:KMQ87403.1, ECO:0000313|Proteomes:UP000036403}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Whole {ECO:0000313|EMBL:KMQ87403.1};
RA   Konorov E.A., Nikitin M.A., Kirill M.V., Chang P.;
RT   "Lasius niger genome sequencing.";
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KMQ87403.1}.
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DR   EMBL; LBMM01010539; KMQ87403.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0J7KAF3; -.
DR   STRING; 67767.A0A0J7KAF3; -.
DR   PaxDb; 67767-A0A0J7KAF3; -.
DR   OrthoDB; 462435at2759; -.
DR   Proteomes; UP000036403; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0006816; P:calcium ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0007154; P:cell communication; IEA:InterPro.
DR   Gene3D; 2.60.40.2030; -; 1.
DR   Gene3D; 1.20.1420.30; NCX, central ion-binding region; 1.
DR   InterPro; IPR038081; CalX-like_sf.
DR   InterPro; IPR003644; Calx_beta.
DR   InterPro; IPR032452; Na_Ca_Ex_C-exten.
DR   InterPro; IPR004837; NaCa_Exmemb.
DR   InterPro; IPR044880; NCX_ion-bd_dom_sf.
DR   PANTHER; PTHR11878:SF65; NA_CA-EXCHANGE PROTEIN, ISOFORM G; 1.
DR   PANTHER; PTHR11878; SODIUM/CALCIUM EXCHANGER; 1.
DR   Pfam; PF03160; Calx-beta; 1.
DR   Pfam; PF01699; Na_Ca_ex; 1.
DR   Pfam; PF16494; Na_Ca_ex_C; 1.
DR   SMART; SM00237; Calx_beta; 1.
DR   SUPFAM; SSF141072; CalX-like; 1.
PE   4: Predicted;
KW   Antiport {ECO:0000256|ARBA:ARBA00022449};
KW   Calcium {ECO:0000256|ARBA:ARBA00022568};
KW   Calcium transport {ECO:0000256|ARBA:ARBA00022568};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Ion transport {ECO:0000256|ARBA:ARBA00022568};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000036403};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Signal {ECO:0000256|ARBA:ARBA00022729};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022568}.
FT   TRANSMEM        29..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        92..113
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        125..146
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        158..181
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        187..207
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          351..452
FT                   /note="Calx-beta"
FT                   /evidence="ECO:0000259|SMART:SM00237"
FT   COILED          334..361
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   NON_TER         452
FT                   /evidence="ECO:0000313|EMBL:KMQ87403.1"
SQ   SEQUENCE   452 AA;  50827 MW;  2F89FE446E8E2F7B CRC64;
     MSGNYSVRCE PGLVIPLWRP VENLHLIDII FRGLVYFFLL LYLFIGVSII SDRFMAAIEV
     ITSKEKELVV RRHGREPQII IVRVWNETVA NLTLMALGSS APEILLSIIE IWAKNFQAGE
     LGPGTIVGSA AYNLFVIISL CVFVIPNGES RKIKHLRVFF VTATWSIFAY VWLYIILAIS
     SPGVLEVWEG ILTFLFFPAT VLTAYVADRR LLIYKYLHKG YRMNKRGVIV QAEAGDSEIG
     VELEIKPQQD GLHGMVDRLA DIDSPEAKEF EQTRRDYINT LKELRKKYPT LPLEQLEVMA
     HEEVLGKGPK SRAFYRVQAT RKMVGAGNLS RKISERAQSD LSEVKAELQK AEAESIDIEN
     VNAMRVFFEP GHYTVMENVG SFEVGVTRAG GDLNKACSVD YCTEDGSAEA GSDYVSAKGT
     LTFESGETKK SIKLSVIDDE LFEEDEHFYV RS
//