ID A0A0J7KEK4_LASNI Unreviewed; 631 AA.
AC A0A0J7KEK4;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=alanine--tRNA ligase {ECO:0000256|ARBA:ARBA00013168};
DE EC=6.1.1.7 {ECO:0000256|ARBA:ARBA00013168};
GN ORFNames=RF55_11887 {ECO:0000313|EMBL:KMQ88601.1};
OS Lasius niger (Black garden ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Formicinae; Lasius; Lasius.
OX NCBI_TaxID=67767 {ECO:0000313|EMBL:KMQ88601.1, ECO:0000313|Proteomes:UP000036403};
RN [1] {ECO:0000313|EMBL:KMQ88601.1, ECO:0000313|Proteomes:UP000036403}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Whole {ECO:0000313|EMBL:KMQ88601.1};
RA Konorov E.A., Nikitin M.A., Kirill M.V., Chang P.;
RT "Lasius niger genome sequencing.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase family.
CC {ECO:0000256|ARBA:ARBA00008226}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KMQ88601.1}.
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DR EMBL; LBMM01008837; KMQ88601.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0J7KEK4; -.
DR STRING; 67767.A0A0J7KEK4; -.
DR PaxDb; 67767-A0A0J7KEK4; -.
DR OrthoDB; 3639120at2759; -.
DR Proteomes; UP000036403; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0004813; F:alanine-tRNA ligase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006419; P:alanyl-tRNA aminoacylation; IEA:InterPro.
DR CDD; cd00673; AlaRS_core; 1.
DR Gene3D; 2.40.30.130; -; 1.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR002318; Ala-tRNA-lgiase_IIc.
DR InterPro; IPR018162; Ala-tRNA-ligase_IIc_anticod-bd.
DR InterPro; IPR018165; Ala-tRNA-synth_IIc_core.
DR InterPro; IPR018164; Ala-tRNA-synth_IIc_N.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR PANTHER; PTHR11777:SF9; ALANINE--TRNA LIGASE, CYTOPLASMIC; 1.
DR PANTHER; PTHR11777; ALANYL-TRNA SYNTHETASE; 1.
DR Pfam; PF01411; tRNA-synt_2c; 2.
DR PRINTS; PR00980; TRNASYNTHALA.
DR SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR SUPFAM; SSF101353; Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS); 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS50860; AA_TRNA_LIGASE_II_ALA; 1.
PE 3: Inferred from homology;
KW Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000036403};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW tRNA-binding {ECO:0000256|ARBA:ARBA00022555}.
FT DOMAIN 17..631
FT /note="Alanyl-transfer RNA synthetases family profile"
FT /evidence="ECO:0000259|PROSITE:PS50860"
SQ SEQUENCE 631 AA; 71794 MW; 3B74A78EAAA73082 CRC64;
MAYYKLIRSY NQSSNNKPAN LIRKEFLDYF SKDLKHSIIR SSPVSPIADQ TLAFINAGMN
QFKGIFLDYY EPPVTKVVNS QKCIRVGGKH NDLSVVGNDS YHHTFFEMLG NWSFGDYFKE
DACTYAWNLL TNVYGIPEEC LYVTYFGGNE KLGMGPDLEC KNIWLKLGLP ECKVLPFGIR
ENFWEMGVSG PCGPCTEIHV DYMKRSTNQA ARVNKGYADL MELWNIVFIQ YERLANGCIV
PLPKHHVDTG MGLERLVTFL QGKKSNYDTD LFQPLFDAIQ KHSNAPKYKG TFSDDDTGKI
DYGYRILADH ARMVTVALAD NMLPEQHQKL RRILRNAIDV GEKIFKKPGI VTELACTVAD
NLGAAYPELC HNLKQVQRII DFEEDLFKRL RNTSGKKWNK MVEVRPELAS ITDWMASGLV
DGYKELQSML KELHKTNVLP GSVAFKLYDT YGLNSETIAE LAQVESLHFD QIDFEKQLDN
CRYQSRIGLD KCSILTKESL RILEENHVSK TNDSFKYNYI YNGSNYEFPA LNSKLIGIII
NGELVINRND SKTTKINNVN NRKAININEM LNSTNEIGII LDKTVCYSLE GGQVSDKGNI
CIKNLLFNID SVRKVNGYVI HSGHFAKTDL L
//
