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Database: UniProt
Entry: A0A0J7KKJ4_LASNI
LinkDB: A0A0J7KKJ4_LASNI
Original site: A0A0J7KKJ4_LASNI 
ID   A0A0J7KKJ4_LASNI        Unreviewed;      1093 AA.
AC   A0A0J7KKJ4;
DT   14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2015, sequence version 1.
DT   03-JUL-2019, entry version 19.
DE   RecName: Full=DNA polymerase {ECO:0000256|RuleBase:RU000442};
DE            EC=2.7.7.7 {ECO:0000256|RuleBase:RU000442};
GN   ORFNames=RF55_9256 {ECO:0000313|EMBL:KMQ90933.1};
OS   Lasius niger (Black garden ant).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Hymenoptera; Apocrita; Aculeata;
OC   Formicoidea; Formicidae; Formicinae; Lasius; Lasius.
OX   NCBI_TaxID=67767 {ECO:0000313|EMBL:KMQ90933.1, ECO:0000313|Proteomes:UP000036403};
RN   [1] {ECO:0000313|EMBL:KMQ90933.1, ECO:0000313|Proteomes:UP000036403}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   TISSUE=Whole {ECO:0000313|EMBL:KMQ90933.1};
RA   Konorov E.A., Nikitin M.A., Kirill M.V., Chang P.;
RT   "Lasius niger genome sequencing.";
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC         diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-
CC         COMP:11130, Rhea:RHEA-COMP:11131, ChEBI:CHEBI:33019,
CC         ChEBI:CHEBI:61560, ChEBI:CHEBI:83828; EC=2.7.7.7;
CC         Evidence={ECO:0000256|RuleBase:RU000442};
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000256|RuleBase:RU000442};
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU000442}.
CC   -!- SIMILARITY: Belongs to the DNA polymerase type-B family.
CC       {ECO:0000256|RuleBase:RU000442}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KMQ90933.1}.
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DR   EMBL; LBMM01006107; KMQ90933.1; -; Genomic_DNA.
DR   OrthoDB; 20210at2759; -.
DR   Proteomes; UP000036403; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.132.60; -; 1.
DR   Gene3D; 3.30.420.10; -; 1.
DR   Gene3D; 3.90.1600.10; -; 1.
DR   InterPro; IPR006172; DNA-dir_DNA_pol_B.
DR   InterPro; IPR017964; DNA-dir_DNA_pol_B_CS.
DR   InterPro; IPR006133; DNA-dir_DNA_pol_B_exonuc.
DR   InterPro; IPR006134; DNA-dir_DNA_pol_B_multi_dom.
DR   InterPro; IPR042087; DNA_pol_B_C.
DR   InterPro; IPR023211; DNA_pol_palm_dom_sf.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR025687; Znf-C4pol.
DR   Pfam; PF00136; DNA_pol_B; 1.
DR   Pfam; PF03104; DNA_pol_B_exo1; 1.
DR   Pfam; PF14260; zf-C4pol; 1.
DR   PRINTS; PR00106; DNAPOLB.
DR   SMART; SM00486; POLBc; 1.
DR   SUPFAM; SSF53098; SSF53098; 1.
DR   PROSITE; PS00116; DNA_POLYMERASE_B; 1.
PE   3: Inferred from homology;
KW   4Fe-4S {ECO:0000256|RuleBase:RU000442};
KW   Complete proteome {ECO:0000313|Proteomes:UP000036403};
KW   DNA replication {ECO:0000256|RuleBase:RU000442};
KW   DNA-binding {ECO:0000256|RuleBase:RU000442};
KW   DNA-directed DNA polymerase {ECO:0000256|RuleBase:RU000442};
KW   Iron {ECO:0000256|RuleBase:RU000442};
KW   Iron-sulfur {ECO:0000256|RuleBase:RU000442};
KW   Metal-binding {ECO:0000256|RuleBase:RU000442};
KW   Nucleotidyltransferase {ECO:0000256|RuleBase:RU000442};
KW   Nucleus {ECO:0000256|RuleBase:RU000442};
KW   Reference proteome {ECO:0000313|Proteomes:UP000036403};
KW   Transferase {ECO:0000256|RuleBase:RU000442};
KW   Zinc {ECO:0000256|RuleBase:RU000442};
KW   Zinc-finger {ECO:0000256|RuleBase:RU000442}.
FT   DOMAIN      116    466       DNA_pol_B_exo1. {ECO:0000259|Pfam:
FT                                PF03104}.
FT   DOMAIN      531    960       DNA_pol_B. {ECO:0000259|Pfam:PF00136}.
FT   DOMAIN      998   1071       zf-C4pol. {ECO:0000259|Pfam:PF14260}.
FT   REGION        1     30       Disordered. {ECO:0000256|MobiDB-lite:
FT                                A0A0J7KKJ4}.
FT   COMPBIAS     16     30       Polyampholyte. {ECO:0000256|MobiDB-lite:
FT                                A0A0J7KKJ4}.
SQ   SEQUENCE   1093 AA;  124457 MW;  E95CE036957E6574 CRC64;
     MSKISRKPFS APKGVVKKAK FRDEDEEKPS SFEAELATMD YMDDDFLDET LVIGEGPEQE
     NTSAKWSRAP PPPLNPQIDT LAFQQIEIDH YICKPIFGMP GSKVGPVPVM RMFGVTELGN
     SICCHVHGFC PYLFVSAPSN FTNNHCKSFK EALNQAVKKD MKSNPDNIQE AILAVELVYK
     QSMYGYGGND KLPFLKITVA VPKLIAPCKR LLEQDTVYTV FNHHYRAFES NIDFDIRFMV
     DTSVVGCSWI ELPPKSWKLR GQYGHMLELT TRCQLEVDVA WDAFIAHAPE GEWSKLAPFR
     ILSFDIECAG REGIFPEAKH DPVIQIANMV IRQGESEPFL RNIFTLDTCA PIVGCQVLSF
     DKENLMLEKW ADFVRQLDPD IFTGYNINNF DFPYLINRAQ HLNVKNFNFL GRIKNIKSVI
     KDHVLQSKQL GRRENKSINF EGRVPFDLLL VLVRDYKLRS YSLNAVSYHF LQEQKEDVHH
     KDITGLQNGN SQTRRRLAVY CLKDAYLPLR LLDKLMCIII YMEMARVTGV SISSLLTRGQ
     QIKVVSQLLR KTREKDYLMP VHQGHSTDEQ FEGATVIEPK RGYYNDPIAT LDFSSLYPSI
     IMAHNLCYTT LLTITKKKEL NIQEDQITTT PSNSLFIKGA VRKGILPEIL ENLLTARKRA
     KAELKQETDP LKQKVLDGRQ YALKVSANSV YGFTGAQMGK LPCLEISASV TAYGRTMIEH
     TKQEVEEHFR IENGYKNDAI VIYGDTDSVM VKFGVKSIED AMELGKEAAD YVTSKFIKPI
     KLEFEKVYFP YLLINKKRYA GLYFTKPDKY DKMDCKGLET VRRDNCPLVA NMMNTCLQIL
     LIERNPHAAV DYAKQIISDL LCNRIDLSQL VITKELTKTD YAAKQAHVEL AAKMKKRDAG
     NAPKLGDRVA YVFTSAAKGT PAYQKAEDPV YALQNSIPID TTYYLENQLA KPLIRIFEPI
     LGEKAESLLL KGDHTRTKCI ATSQVGALAA FTRKKETCLG CKAVLPSDRE DKAVCKHCES
     QEAELFHNEL QAQQKLEEKF SRLWTECQRC QGSLHQEVIC SNRDCPIFYM RVKSRMDMAA
     KAKRIQRFGI PEW
//
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