ID A0A0J7L3G4_LASNI Unreviewed; 1917 AA.
AC A0A0J7L3G4;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 08-NOV-2023, entry version 37.
DE SubName: Full=Myotubularin-related protein 13 {ECO:0000313|EMBL:KMQ97196.1};
GN ORFNames=RF55_2483 {ECO:0000313|EMBL:KMQ97196.1};
OS Lasius niger (Black garden ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Formicinae; Lasius; Lasius.
OX NCBI_TaxID=67767 {ECO:0000313|EMBL:KMQ97196.1, ECO:0000313|Proteomes:UP000036403};
RN [1] {ECO:0000313|EMBL:KMQ97196.1, ECO:0000313|Proteomes:UP000036403}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Whole {ECO:0000313|EMBL:KMQ97196.1};
RA Konorov E.A., Nikitin M.A., Kirill M.V., Chang P.;
RT "Lasius niger genome sequencing.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the protein-tyrosine phosphatase family. Non-
CC receptor class myotubularin subfamily. {ECO:0000256|ARBA:ARBA00007471}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KMQ97196.1}.
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DR EMBL; LBMM01000932; KMQ97196.1; -; Genomic_DNA.
DR STRING; 67767.A0A0J7L3G4; -.
DR PaxDb; 67767-A0A0J7L3G4; -.
DR OrthoDB; 3195274at2759; -.
DR Proteomes; UP000036403; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd13208; PH-GRAM_MTMR5_MTMR13; 1.
DR CDD; cd01235; PH_Sbf1_hMTMR5; 1.
DR CDD; cd14534; PTP-MTMR5-like; 1.
DR Gene3D; 3.30.60.20; -; 1.
DR Gene3D; 3.40.50.11500; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR046349; C1-like_sf.
DR InterPro; IPR001194; cDENN_dom.
DR InterPro; IPR005112; dDENN_dom.
DR InterPro; IPR043153; DENN_C.
DR InterPro; IPR004182; GRAM.
DR InterPro; IPR010569; Myotubularin-like_Pase_dom.
DR InterPro; IPR030564; Myotubularin_fam.
DR InterPro; IPR002219; PE/DAG-bd.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR022096; SBF1/SBF2.
DR InterPro; IPR037516; Tripartite_DENN.
DR PANTHER; PTHR10807; MYOTUBULARIN-RELATED; 1.
DR PANTHER; PTHR10807:SF109; SET DOMAIN BINDING FACTOR, ISOFORM A; 1.
DR Pfam; PF00130; C1_1; 1.
DR Pfam; PF02141; DENN; 1.
DR Pfam; PF02893; GRAM; 1.
DR Pfam; PF06602; Myotub-related; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF12335; SBF2; 1.
DR SMART; SM00109; C1; 1.
DR SMART; SM00801; dDENN; 1.
DR SMART; SM00799; DENN; 1.
DR SMART; SM00568; GRAM; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR SUPFAM; SSF57889; Cysteine-rich domain; 1.
DR SUPFAM; SSF50729; PH domain-like; 2.
DR PROSITE; PS50211; DENN; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS51339; PPASE_MYOTUBULARIN; 1.
DR PROSITE; PS00479; ZF_DAG_PE_1; 1.
DR PROSITE; PS50081; ZF_DAG_PE_2; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000036403};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 1..322
FT /note="UDENN"
FT /evidence="ECO:0000259|PROSITE:PS50211"
FT DOMAIN 1033..1575
FT /note="Myotubularin phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS51339"
FT DOMAIN 1713..1763
FT /note="Phorbol-ester/DAG-type"
FT /evidence="ECO:0000259|PROSITE:PS50081"
FT DOMAIN 1813..1917
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 688..717
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1198..1262
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1203..1222
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1237..1251
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1917 AA; 215601 MW; 7EDDFBF9BF437EFF CRC64;
MCFNETVSIV PSKPVDEEED PVDGDSRPLV RAIPTIAHHS IMYAPKCLVL VSRLDYIETF
RNCLGIIYTV YVENLGIPLE TLVGNILGCI QVPPAGGPQQ LGIRNVLVLF CAVMTEHKIL
FHSASYSRLT EGCRALTALM YPFRYSHVYI PLLPAALVEI LSTPTPFIMG VHSSLKYEVA
ELMDVIVADL DGGSITVPDG VSLALLPEPL LSQTQDALSL VLQPELTCAD YAFPPLATRA
PHSPMLDKEL RAVFMRTFAQ LLQGYRSCLT LIRIHPKPVI TFHKAAFLGE RGLTDCDFTT
RVLDCMFFTS FIAERGPPWR PCDVWDELYS NLSDQLKQET QDHRVILTHI QELAQQLYLN
ENPNPQPYVQ KILKPPEGAF ARIHQPLLPR INLEQVQAII DEGLAKNNLK VRLSSLRPIQ
PRIVPMGPHI SFVHDTRHLV SNSARRLEVL RNCINCIFEN KISDARKTFP AVLRALKSKA
ARLALCMELS QHVVGNKAML EHQQFDLVVR LMNCALQDDS SMDEHGVAAA LLPLATAFCR
KLCTGVIQFA YTCIQEHPVW QNQQFWEDAF YLDVQKDIKR LYLPGDNSPP RLINDGILSP
ISPRDGKEFP YRDRYSIYQA QEPSALEIAA DQMRIWPSID SEKQKELVNS EESTMYSQAI
HYANRMVYLL VPLDIGSKTH RQDHVYDDER ASNSITNSVA SDSGDAESGF EETDPNETGS
AVIRMVSRFV DRVCTEGGVS AEHVRCLHQM VPGVVHMHIE TLEAVHRESK RLPPIQKPKI
LTPNMLPGEE VIMDGLRVYL LPDGREESSA GLPKIPPLLP AEGAIFLTNY RIVFKGIPCD
PFACEQLVVR AFPVTSLTKE KRVAVQHLAH LDQCLQEGLQ LRSCTFQLIK LAFDEEVTPE
NIDTLRKLVH KARYPPHIFH HFAFNGQILV TQTAHHKNKE KNATLKGFAK KTLLKTARKA
GFKPKQSSKR QKYVLPNMNL INSNNKYMTS PGRMSLPMTD NNDLSHDDDL SVDDFEIPGM
VTQPPTDAKT LERLSERSYV RDWYRLGLYS NGPHNNRRNE PFRLTSVNCA YMICRSYPAL
LIVPTSVSDE SIRRFCRLHR HSRMPVVTWR HPRTKALLIR GAGYHGKGVM GMLKAHPTSS
SNLKTTSSET TSSLEQEKYM MALVAATPLS VLRQGSAWGM SDSSLSIDSL LLAAEDRNAT
PEQSRRNPFN KPLSTFSSSG GKGPKNFGRW GSLKDKRHNS QASLTSVHHQ RGTVRHSADS
DSGTECVHTF QRAALYILGE KAHMKGVKAE SVPKTDFIPV EYYDVRHTKA AFKKLMRACV
PSSPNVEPDQ SFYRLIESSE WLQQLQNLMQ LAGAVIDLMD MQGSSVAVCL EDGWDTTTTV
CSVAQVCLDP HYRTIDGFRI LIEKEWLGFG HRFGHRSNLA ANSQTTNFTP TFLQFLDIVH
QIQKQFPLAF EFNEYYLKFL AYHSVSCRFR TFLLDCEFDR VECGITAIED KRGSLTSHHK
GVDTGSDDDT IYPGGRLAGT GNPGCNLGQS IFDYVEKQHA RCPLFYNFMY TPNTENPVLR
PVSHLPSLDI WQFYLEEELA HGPAYDLEVL QQDSQQEEEA EAADGVVKSN RKVVTQGYDG
VSAMVPDQFS HLLEEIHKLE TELGHLPQKW KVLWDKLELP NTDSLARHAS FSTALVRYHG
RLIHKRSTLE LLLRGKLAGG NTTGNEGSVY AHPHRFERLD SATPTHCDAC SGVLWGPVKA
GLRCIDCGHV CHDKCADAVP KNCTKYKAVT DNLQTHTLTR SGGDNGSVNS SVTTIQTSSQ
QYYEQFSSNV AENRTHEGYL YKRGALLKGW KQRWFVLDSI KHQLRYYDAV EDSHCKGYID
LAEVVSVTPA APMPGPPKKT DDKSFFDLRT NRRTYNFCAA DAATAQEWIE KVQACLQ
//
