ID A0A0J7LBZ0_LASNI Unreviewed; 585 AA.
AC A0A0J7LBZ0;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 08-NOV-2023, entry version 31.
DE SubName: Full=Frizzled-like protein {ECO:0000313|EMBL:KMR05343.1};
GN ORFNames=RF55_46 {ECO:0000313|EMBL:KMR05343.1};
OS Lasius niger (Black garden ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Formicinae; Lasius; Lasius.
OX NCBI_TaxID=67767 {ECO:0000313|EMBL:KMR05343.1, ECO:0000313|Proteomes:UP000036403};
RN [1] {ECO:0000313|EMBL:KMR05343.1, ECO:0000313|Proteomes:UP000036403}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Whole {ECO:0000313|EMBL:KMR05343.1};
RA Konorov E.A., Nikitin M.A., Kirill M.V., Chang P.;
RT "Lasius niger genome sequencing.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor Fz/Smo family.
CC {ECO:0000256|ARBA:ARBA00008077}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00090}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KMR05343.1}.
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DR EMBL; LBMM01000015; KMR05343.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0J7LBZ0; -.
DR STRING; 67767.A0A0J7LBZ0; -.
DR PaxDb; 67767-A0A0J7LBZ0; -.
DR OrthoDB; 5483535at2759; -.
DR Proteomes; UP000036403; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR CDD; cd15034; 7tmF_FZD1_2_7-like; 1.
DR CDD; cd07458; CRD_FZ1_like; 1.
DR Gene3D; 1.10.2000.10; Frizzled cysteine-rich domain; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR015526; Frizzled/SFRP.
DR InterPro; IPR000539; Frizzled/Smoothened_7TM.
DR InterPro; IPR020067; Frizzled_dom.
DR InterPro; IPR036790; Frizzled_dom_sf.
DR InterPro; IPR017981; GPCR_2-like_7TM.
DR PANTHER; PTHR11309; FRIZZLED; 1.
DR PANTHER; PTHR11309:SF47; FRIZZLED; 1.
DR Pfam; PF01534; Frizzled; 1.
DR Pfam; PF01392; Fz; 1.
DR PRINTS; PR00489; FRIZZLED.
DR SMART; SM00063; FRI; 1.
DR SMART; SM01330; Frizzled; 1.
DR SUPFAM; SSF63501; Frizzled cysteine-rich domain; 1.
DR PROSITE; PS50038; FZ; 1.
DR PROSITE; PS50261; G_PROTEIN_RECEP_F2_4; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00090}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000036403};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..585
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5005290677"
FT TRANSMEM 252..274
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 286..306
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 345..370
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 423..451
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 472..495
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 543..561
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 36..155
FT /note="FZ"
FT /evidence="ECO:0000259|PROSITE:PS50038"
FT DOMAIN 250..568
FT /note="G-protein coupled receptors family 2 profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50261"
FT DISULFID 41..102
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00090"
FT DISULFID 49..95
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00090"
FT DISULFID 116..140
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00090"
SQ SEQUENCE 585 AA; 65318 MW; 8C7D3C76BDE75D09 CRC64;
MPWTAMIGVM ILSSVVAVTA ALHSSTALNG GGDSLPHHGR CEPITINLCM NIPYNETIMP
NLMNHQKQED AGQEVHQYVP LVKMKCSPDL RFFLCTVYAP VCTIIEKAIP PCRSLCESAR
SGCEGLMNSF GFAWPEALDC SKMPENDGTE LCVGTNETTT PQEPAAPVYP PPRMPVAEFQ
PPWNEGAKPY GGTGANGFAI GARDFGFVCP VQFKVPHGLG YSLKVGDKVE ADCGAPCDGM
FFTERERRFS RVWVGTWASI CAASCFFTFL TFLIDTDRFR YPERPIIFLS VCYLMVALVY
VIGWAAGNSI ACREPFPPPM GIRLQMPSTI TQGTKHELCT VLFMVLYFFG MASSIWWVIL
TLTWFLAAGL KWGHEAIETN SQYFHLAAWA APAVKTVTIL AMGKVEGDIL SGVCYVGLWN
VEALRGFVLA PLCVYLLLGT AFLLAGFVSL FRIRTVMKHD GTKTDKLEKL MIRIGIFSVL
YIVPALIVIA CLFYEQAHFD QWMLTWNMEM CSRPGPQSLY SLPCPVGERT RDLGRRPEFE
VFMIKYLMAM IVGITSSFWV WSKKTLTSWQ QFFHHIRGHR AEAYV
//
