ID   A0A0J7ZAT9_STRVR        Unreviewed;       449 AA.
AC   A0A0J7ZAT9;
DT   14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2015, sequence version 1.
DT   24-JAN-2024, entry version 36.
DE   SubName: Full=Uracil permease {ECO:0000313|EMBL:KMS72939.1};
GN   ORFNames=ACM01_20745 {ECO:0000313|EMBL:KMS72939.1};
OS   Streptomyces viridochromogenes.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1938 {ECO:0000313|EMBL:KMS72939.1, ECO:0000313|Proteomes:UP000037432};
RN   [1] {ECO:0000313|EMBL:KMS72939.1, ECO:0000313|Proteomes:UP000037432}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL 3414 {ECO:0000313|EMBL:KMS72939.1,
RC   ECO:0000313|Proteomes:UP000037432};
RA   Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL   Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC       2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KMS72939.1}.
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DR   EMBL; LFNT01000023; KMS72939.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0J7ZAT9; -.
DR   PATRIC; fig|1938.3.peg.2619; -.
DR   OrthoDB; 9805749at2; -.
DR   Proteomes; UP000037432; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR   GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:UniProt.
DR   InterPro; IPR006043; NCS2.
DR   InterPro; IPR017588; UacT-like.
DR   InterPro; IPR006042; Xan_ur_permease.
DR   NCBIfam; TIGR00801; ncs2; 1.
DR   NCBIfam; NF037981; NCS2_1; 1.
DR   NCBIfam; TIGR03173; pbuX; 1.
DR   PANTHER; PTHR42810; PURINE PERMEASE C1399.01C-RELATED; 1.
DR   PANTHER; PTHR42810:SF4; URIC ACID TRANSPORTER UACT; 1.
DR   Pfam; PF00860; Xan_ur_permease; 1.
DR   PROSITE; PS01116; XANTH_URACIL_PERMASE; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        12..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        36..57
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        64..84
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        90..112
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        119..143
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        155..172
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        184..201
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        221..240
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        306..329
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        335..355
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        367..389
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        395..415
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          426..449
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   449 AA;  45823 MW;  A2227C127ED8D48C CRC64;
     MATTGLQHVA AMYAGVVAPP LIVGAAIGLS ATDLTFLTGA CLFTAGLATF LQTLGIWKIG
     ARLPFVNGVT FAGVAPMTAV VASTEDKSDA LPIIFGAVIV AGLLGFLAAP FFSKAVRFFP
     PVVTGTVITL IGISLLPVAF NWAQGPDPAA NDYGSGTNLG LAAGTLLVVL LLRRFTKGFV
     KQIAVLLGLV VGTLIAIPFG VTDFGPVADA DVIGFPTPFH FGAPQFQLAA IISLCVVMVV
     SMTESTADML ALGEIVERPA DEKTIAAGLR ADTLGSAISP LFNGFMCSAF AQNIGLVAMT
     KIRSRYVVAV GGGFLVLMGL CPMAASLIAV VPRPVLGGAG VVLFGSVAAS GIQTLVRAGL
     DKDNNVLIVA VSLAVGIVPI TAPEFYHAFP ETARIVLDSG ISTGCVAAVL LNLVFNHLGK
     GGRDAHDVTH PMEAGEEITG TATRAPATP
//