ID A0A0J8FZ44_CLOCY Unreviewed; 620 AA.
AC A0A0J8FZ44;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Lipoteichoic acid synthase-like YqgS {ECO:0000313|EMBL:KMT20891.1};
GN Name=yqgS {ECO:0000313|EMBL:KMT20891.1};
GN ORFNames=CLCY_1c01250 {ECO:0000313|EMBL:KMT20891.1};
OS Clostridium cylindrosporum DSM 605.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1121307 {ECO:0000313|EMBL:KMT20891.1, ECO:0000313|Proteomes:UP000036756};
RN [1] {ECO:0000313|EMBL:KMT20891.1, ECO:0000313|Proteomes:UP000036756}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 605 {ECO:0000313|EMBL:KMT20891.1,
RC ECO:0000313|Proteomes:UP000036756};
RA Poehlein A., Schiel-Bengelsdorf B., Bengelsdorf F., Daniel R., Duerre P.;
RT "Draft genome sequence of the purine-degrading Clostridium cylindrosporum
RT HC-1 (DSM 605).";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Cell wall biogenesis; lipoteichoic acid biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004936}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the LTA synthase family.
CC {ECO:0000256|ARBA:ARBA00009983}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KMT20891.1}.
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DR EMBL; LFVU01000028; KMT20891.1; -; Genomic_DNA.
DR RefSeq; WP_048571293.1; NZ_LFVU01000028.1.
DR AlphaFoldDB; A0A0J8FZ44; -.
DR STRING; 1121307.CLCY_1c01250; -.
DR PATRIC; fig|1121307.3.peg.486; -.
DR OrthoDB; 5901192at2; -.
DR Proteomes; UP000036756; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd16015; LTA_synthase; 1.
DR Gene3D; 3.30.1120.170; -; 1.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR012160; LtaS-like.
DR InterPro; IPR000917; Sulfatase_N.
DR PANTHER; PTHR47371; LIPOTEICHOIC ACID SYNTHASE; 1.
DR PANTHER; PTHR47371:SF3; PHOSPHOGLYCEROL TRANSFERASE I; 1.
DR Pfam; PF00884; Sulfatase; 1.
DR PIRSF; PIRSF005091; Mmb_sulf_HI1246; 1.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Manganese {ECO:0000256|PIRSR:PIRSR005091-2};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR005091-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000036756};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 37..58
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 65..81
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 111..134
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 155..173
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 249..539
FT /note="Sulfatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00884"
FT ACT_SITE 299
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-1"
FT BINDING 257
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-3"
FT BINDING 299
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-3"
FT BINDING 412
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-2"
FT BINDING 473
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-3"
FT BINDING 474
FT /ligand="Mn(2+)"
FT /ligand_id="ChEBI:CHEBI:29035"
FT /evidence="ECO:0000256|PIRSR:PIRSR005091-3"
SQ SEQUENCE 620 AA; 71009 MW; 5F23D81D9950819F CRC64;
MNSTQKILKN NLDILLFISI IFLKLISSNI TLKLNGLSFY TIIGCLGSVL VLLGFSYFFT
KRIRIPIFFV INIIVTLIIY IDNVYNRYFL DVTTIGLIKQ LGITGEVKDS VFNLITIFDL
LYILDLIILI PFYLKNKREI TRGELKFNKR VISSISMLII GFMLSALSVI GLAKMQVGIL
NSFYDKKAIV REVGLLNYHV LDINKYINNY MLKKSSITED EKAQVEAFFE NKNKTSLNNP
KYNGIAKGKN LIVIQLEAFQ SFVLNKKING VEITPNLNKL AKESLNFKNY YFQTSLGGTS
DAEFLSNTSL LPAREGSVYY QYAQNEYNSL PKSLKESGYY TAVMHANRPG FWNRQEMYKA
LGFDTFQSEK NYKIDDVKIL GLSDKSFFRQ NIEKLKSYPK PFYGFMISLT SHFSFRDEKN
SLKDVMNVGE YEGSLVGDYI KTARYTDEAL GQFLNDLKKE GLYDNTVIAI YGDHSAISSD
KRDQLAKVVY GKETISEFEW QEAQKVVSMI HIPGSNLKGD VDSVAGQYDL YPTLANLFGF
KTKVTLGQDL LNKSEGFVVT RAGNFVTDSV IYVKAEDKIY DRKTKKELNK KDYQKYFDKM
NEYFTVTDKI IENNLIKVFN
//
