ID A0A0J8G1R2_CLOCY Unreviewed; 530 AA.
AC A0A0J8G1R2;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=Flagellar hook-associated protein 2 {ECO:0000256|RuleBase:RU362066};
DE Short=HAP2 {ECO:0000256|RuleBase:RU362066};
DE AltName: Full=Flagellar cap protein {ECO:0000256|RuleBase:RU362066};
GN Name=fliD {ECO:0000313|EMBL:KMT21691.1};
GN ORFNames=CLCY_2c04530 {ECO:0000313|EMBL:KMT21691.1};
OS Clostridium cylindrosporum DSM 605.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1121307 {ECO:0000313|EMBL:KMT21691.1, ECO:0000313|Proteomes:UP000036756};
RN [1] {ECO:0000313|EMBL:KMT21691.1, ECO:0000313|Proteomes:UP000036756}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 605 {ECO:0000313|EMBL:KMT21691.1,
RC ECO:0000313|Proteomes:UP000036756};
RA Poehlein A., Schiel-Bengelsdorf B., Bengelsdorf F., Daniel R., Duerre P.;
RT "Draft genome sequence of the purine-degrading Clostridium cylindrosporum
RT HC-1 (DSM 605).";
RL Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for morphogenesis and for the elongation of the
CC flagellar filament by facilitating polymerization of the flagellin
CC monomers at the tip of growing filament. Forms a capping structure,
CC which prevents flagellin subunits (transported through the central
CC channel of the flagellum) from leaking out without polymerization at
CC the distal end. {ECO:0000256|RuleBase:RU362066}.
CC -!- SUBUNIT: Homopentamer. {ECO:0000256|ARBA:ARBA00011255,
CC ECO:0000256|RuleBase:RU362066}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|RuleBase:RU362066}.
CC Bacterial flagellum {ECO:0000256|RuleBase:RU362066}.
CC -!- SIMILARITY: Belongs to the FliD family. {ECO:0000256|ARBA:ARBA00009764,
CC ECO:0000256|RuleBase:RU362066}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KMT21691.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LFVU01000027; KMT21691.1; -; Genomic_DNA.
DR RefSeq; WP_048571107.1; NZ_LFVU01000027.1.
DR AlphaFoldDB; A0A0J8G1R2; -.
DR STRING; 1121307.CLCY_2c04530; -.
DR PATRIC; fig|1121307.3.peg.1311; -.
DR OrthoDB; 9776025at2; -.
DR Proteomes; UP000036756; Unassembled WGS sequence.
DR GO; GO:0009421; C:bacterial-type flagellum filament cap; IEA:InterPro.
DR GO; GO:0009424; C:bacterial-type flagellum hook; IEA:UniProtKB-UniRule.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR InterPro; IPR040026; FliD.
DR InterPro; IPR010809; FliD_C.
DR InterPro; IPR003481; FliD_N.
DR PANTHER; PTHR30288; FLAGELLAR CAP/ASSEMBLY PROTEIN FLID; 1.
DR PANTHER; PTHR30288:SF0; FLAGELLAR HOOK-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF07195; FliD_C; 1.
DR Pfam; PF02465; FliD_N; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum {ECO:0000256|ARBA:ARBA00023143,
KW ECO:0000256|RuleBase:RU362066};
KW Cell projection {ECO:0000313|EMBL:KMT21691.1};
KW Cilium {ECO:0000313|EMBL:KMT21691.1};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Flagellum {ECO:0000313|EMBL:KMT21691.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000036756};
KW Secreted {ECO:0000256|RuleBase:RU362066}.
FT DOMAIN 10..114
FT /note="Flagellar hook-associated protein 2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02465"
FT DOMAIN 237..518
FT /note="Flagellar hook-associated protein 2 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07195"
SQ SEQUENCE 530 AA; 58099 MW; D57B50374205D56C CRC64;
MVMRIGGLAS GMDTDTVVKQ MLSREQARVD KVKGQKQILQ WQQETYRDFI GQIQKFKNKY
FDQLNKATYA LSNSFFSSKT STVVGSDSGA VSITPSNTAN SGTYKVDVTT VAKGAKVEAT
LNAKLTDSLS GVGINTGEKI TIKGTGISDT VIEVKDSTKT ISDLVSLINN DTNLKGNINA
SYSEITGKLS IETVNTGNAQ ELTVTDSFSN NNIKFLDSNV QNPIEGQKAL GVNGNIKVTV
NGGASTYTTN KFTVDGIAFN IKDIGTTPTS TTFEVSPNVD KAVDNIKEFV KTYNEMIDGI
ASKIYERKQY KYSPLTDEQK KEMKEDEIKS WESKCKEGII KGDSTLEKML LDMRQAFSTS
IDGKTVKGVS INLKDIGIGT SADFTQRGKL EIDEEKLRTA LKERPDDVAK LFTQESSDYP
YDKKTGYGGN PNRRDNVGIF VRLSDIVEDN IGTIGGKGFL LKKAGITGDI TVTQNTISDT
IKEKDTLLSD LIRKMSDKEA MLYNKFATLE SVMNKYNSQS SWLTQQLGGM
//
