ID A0A0J8QIF8_COCIT Unreviewed; 858 AA.
AC A0A0J8QIF8;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Heat shock protein 104 {ECO:0000313|EMBL:KMU72139.1};
GN ORFNames=CISG_00448 {ECO:0000313|EMBL:KMU72139.1};
OS Coccidioides immitis RMSCC 3703.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=454286 {ECO:0000313|EMBL:KMU72139.1, ECO:0000313|Proteomes:UP000054559};
RN [1] {ECO:0000313|Proteomes:UP000054559}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RMSCC 3703 {ECO:0000313|Proteomes:UP000054559};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC {ECO:0000256|RuleBase:RU004432}.
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DR EMBL; DS268118; KMU72139.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0J8QIF8; -.
DR STRING; 454286.A0A0J8QIF8; -.
DR Proteomes; UP000054559; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR004176; Clp_R_dom.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF194; HEAT SHOCK PROTEIN 104; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF02861; Clp_N; 1.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF81923; Double Clp-N motif; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51903; CLP_R; 1.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS00871; CLPAB_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004432};
KW Chaperone {ECO:0000256|RuleBase:RU004432};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004432};
KW Reference proteome {ECO:0000313|Proteomes:UP000054559};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|PROSITE-
KW ProRule:PRU01251}; Stress response {ECO:0000313|EMBL:KMU72139.1}.
FT DOMAIN 3..139
FT /note="Clp R"
FT /evidence="ECO:0000259|PROSITE:PS51903"
FT COILED 408..522
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 858 AA; 94743 MW; 473CC2BA9007C469 CRC64;
MNTSQFTDRA NEAIQQAGEL ADQFAHPEIA PIHLAVALLN PILAETEDGG KSAPIPLFKQ
VVERAHGDTQ QLDRSLQRAL PKVIRSAKEL AKTQKDSYVA IDHLIIALAG DSTVKRALAD
SNVPDVKMID SAVQQIRGTK RVDSKTADSE VDSEYLKKFT IDMTALAREG KIDPVIGREE
EIRRVIRILS RRTKNNPVLI GEPGVGKTTI VEGLARRIVN ADVPANLAHC KLLSLDVGAL
VAGTKYRGEF EERMKGVLKE IEESKETIVL FVDEMHLLMG AGNSGGGGMD AANLLKPMLA
RGQLHCIGAT TLGEYRKYIE KDQAFERRFQ QVLVKEPSVS ETISILRGLK ERYEVHHGVN
ILDAAIVSAA TLAARYLTAR RLPDSAVDLI DEAAAAVRVA RESQPEAIDT MERRLRQLQI
EIHALEREKD AASKTRLEVA KQEAANVNEE LRPLREKYER EKQRSRDIQD AKMKLDQLKV
KAEEATRSGD MQTASDLVYY AIPDVEKRIE RLEAARARQD AEAVAQAGAE GEALLADAVG
PEQINEIVAR WTGIPVTRLK TSEKDRLLHM ESHLGKIVIG QKEAVQSVSN AIRLQRSGLA
NPNQPPSFLF CGPSGTGKTL LTKALAEFLF DDPKAMIRFD MSEYQERHSL SRMIGAPPGY
VGHDAGGQLT EALRRRPFSI LLFDEVEKAA KEVLTVLLQL MDDGRITDGQ GRIVDASNCI
VVMTSNLGAE YLSRPNTADG TIDATTKELR RLEQNDRNVK ISCTDEVKDY LGKAGYSPAY
GARPLSRLIE KEILNRLAVL ILRGAIKDDE VARVAMQGGH ITVLPNHVGS EDEDEEMIDE
DEAIAELEDD MGDKDLYE
//
