ID   A0A0J8R0J9_COCIT        Unreviewed;      1284 AA.
AC   A0A0J8R0J9;
DT   14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2015, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Pfs {ECO:0000313|EMBL:KMU77168.1};
GN   ORFNames=CISG_06012 {ECO:0000313|EMBL:KMU77168.1};
OS   Coccidioides immitis RMSCC 3703.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX   NCBI_TaxID=454286 {ECO:0000313|EMBL:KMU77168.1, ECO:0000313|Proteomes:UP000054559};
RN   [1] {ECO:0000313|Proteomes:UP000054559}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RMSCC 3703 {ECO:0000313|Proteomes:UP000054559};
RX   PubMed=20516208; DOI=10.1101/gr.103911.109;
RA   Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA   Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA   Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA   FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA   Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA   Taylor J.W., Rounsley S.D.;
RT   "Population genomic sequencing of Coccidioides fungi reveals recent
RT   hybridization and transposon control.";
RL   Genome Res. 20:938-946(2010).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; DS268153; KMU77168.1; -; Genomic_DNA.
DR   STRING; 454286.A0A0J8R0J9; -.
DR   Proteomes; UP000054559; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0009116; P:nucleoside metabolic process; IEA:InterPro.
DR   Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR   Gene3D; 3.40.50.1580; Nucleoside phosphorylase domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR000845; Nucleoside_phosphorylase_d.
DR   InterPro; IPR035994; Nucleoside_phosphorylase_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR46082:SF11; AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR   PANTHER; PTHR46082; ATP/GTP-BINDING PROTEIN-RELATED; 1.
DR   Pfam; PF12796; Ank_2; 1.
DR   Pfam; PF05729; NACHT; 1.
DR   Pfam; PF01048; PNP_UDP_1; 1.
DR   SMART; SM00248; ANK; 4.
DR   SUPFAM; SSF48403; Ankyrin repeat; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF53167; Purine and uridine phosphorylases; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 3.
DR   PROSITE; PS50088; ANK_REPEAT; 3.
DR   PROSITE; PS50837; NACHT; 1.
PE   4: Predicted;
KW   ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054559}.
FT   DOMAIN          360..510
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
FT   REPEAT          831..863
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          864..896
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          897..929
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
SQ   SEQUENCE   1284 AA;  144545 MW;  BEF486DEEA47E166 CRC64;
     MVPPAMLSRG DYTVGWICAL PLELAAAQAI LDTIHEEPLL DPDSNDDNGY VFGSIGDHNV
     VIACLPSGVY GTVSAARVAK QMTTSYKSIR FNLMVGIGGG VPSTKKDTRL GDVVVSKPTA
     TSGGVIQYDL GKRTGPDQLK ITGTLNKPPQ VLLTAAAKLE ARDILGQSQF SRYLSQIIER
     DQNGAFAYPG ADQDHVGEER KVRHRAARKT EAPKVHYGLI ASGNQVMRHG LTRDRLALKN
     GILCFEMEAA GLMDNHPCLV IRGICDYADS HKNKQWQGYA AAAAAAYGKE ILISIPAKPL
     QGPSVVRVRQ SEILNALLLT QPEDDRNSLI IRKGKRVENT CQWIMKNQQY RQWLEQTNSQ
     ILWLSGGPGK GKTILAIYLT EELERCVNLK SGTVLYYFCD NQDEKRNTAL AVLRGLLHQL
     LEQHPYLAQY IEKFFDGVET TSYTVSRFER LWRAFYTLLQ NGGLNEVVCV VDGLDECEDE
     SLKLFLDSLH SLFLGSKPLN TRFKLLLLSR AQPTFIESKL GRFPRLDLDV DCRHELRRDV
     EKYITAKVNE LELEDQLEES RLKIVREALE KGADGTFLWV GFVADELKGK SKHKMEEILT
     KVPKRLGDIY KRILHQMEDK EQLARILQWV VLARRPLTLT ELAIAVDIHD SNTQSCVEIL
     KDQLSSCRQL LKVMGDSVSL IHNSAKDFLL GDVHSGIEAF CVREETHLVL ARTCLDTIEV
     GHKTSNNIRS EPAESTLFPY ASRYWLDHLR QVPDTIEQDL FSRQFFTPNS SARGRWWADY
     WVKEQYGVAP TSFTLLHLAA YLESLHGLKC FLEKKRRSRF PSSPEHMKDS YGRTPLFWAA
     SRGHGEVARL LLDNGANVNS KDKNKLTPLH VATTSEHTKL MTLFLDRGAH IEAKGASGDT
     PLARAIENGS KEVIKVLLER GANEEYLHAQ TRVRPGAHAA TRQVSIEDRA EALLDLQDDL
     LFRRFEKRFE VMGFALGKVL FLLRLKPFFK LIAKYMDYQL DQREASSFEV LRQLVVKDRS
     TGLEKAVRPV IKFCDRVVDS KDIQRLQGLV VVGNKLVQNA LAPGSEALLG VAIQVGVAMF
     QRAVNQQFRE GLDIMGYHSA QSLKIAFEKD KHDVIRREMS QTEEKGVWTC WEPAWSLYKS
     IVFDGDPMTT KVMLNIYADA FGELVRGKYS ESLFSDLTIV LSNDAAYLAR RRDHDAVQTV
     TKCLMLLAER GDDLQTRALK ALIECLILMK QTYPTELGET LGYVKKIFET VKQERILDEK
     DINQILYYIF GISNGDAASD CGSG
//