ID   A0A0J8R126_COCIT        Unreviewed;       947 AA.
AC   A0A0J8R126;
DT   14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2015, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=Transportin-1 {ECO:0000313|EMBL:KMU78030.1};
GN   ORFNames=CISG_06792 {ECO:0000313|EMBL:KMU78030.1};
OS   Coccidioides immitis RMSCC 3703.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX   NCBI_TaxID=454286 {ECO:0000313|EMBL:KMU78030.1, ECO:0000313|Proteomes:UP000054559};
RN   [1] {ECO:0000313|Proteomes:UP000054559}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RMSCC 3703 {ECO:0000313|Proteomes:UP000054559};
RX   PubMed=20516208; DOI=10.1101/gr.103911.109;
RA   Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA   Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA   Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA   FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA   Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA   Taylor J.W., Rounsley S.D.;
RT   "Population genomic sequencing of Coccidioides fungi reveals recent
RT   hybridization and transposon control.";
RL   Genome Res. 20:938-946(2010).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the importin beta family. Importin beta-2
CC       subfamily. {ECO:0000256|ARBA:ARBA00038423}.
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DR   EMBL; DS268159; KMU78030.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0J8R126; -.
DR   STRING; 454286.A0A0J8R126; -.
DR   Proteomes; UP000054559; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR040122; Importin_beta.
DR   PANTHER; PTHR10527:SF3; FI21453P1-RELATED; 1.
DR   PANTHER; PTHR10527; IMPORTIN BETA; 1.
DR   Pfam; PF13513; HEAT_EZ; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000054559}.
FT   REGION          349..410
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        392..408
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   947 AA;  105348 MW;  AC375925CE780B98 CRC64;
     MQRAVQSAIV NMAWQPEEEP LRQLAGFLND SLNGFDHAVQ KHAEHMLAQA TSSPDFVNYL
     SYLICTAQVP SAIGFDANQY VIIRVAAAMN LKTKLRVAYG TITPNSLGYI RSSSMVALQD
     PSGQVRNASG SIISEMVKQG GVLSWPTLFE ELLSLVGNST GSVPIVTQES AMSALEKVCE
     DNRKILDRDY QGQRPLSIIL PKLMEFTASP SPKVRSMALS TVQMFISSRP DALMGALDTF
     VHELFKLAHD QDTDVRKTVC QSIVQLVDVA PDKLAPHMEG LVNYIIMQQN NIEDPELALD
     AAEFWLTVGE QKQLQQSLVP YLGKVIPVLL HNMIYDEDDA ALLAGEEDDA EFEDKEEELR
     PQFAKSKGAR LPSLKSGDQP NGDGKAAQEE DDLSDGEIED DSDYGDDPED EWTVRKCSAA
     ALDVFATVYH QPVFETILPY LRDNLKHAKW TNREAAVLAL GAIADGCMDS VTPHLPELIP
     YLISLLSDPE PIVRKITCWC LGRYSEWAAH LEPTEKARFF EPMMEGILHR MLDNNKKVQE
     AAASAFTSLE EKSDANLIPY CQPILRQFVL CFQKYKDRNM YVLYDCVQTL AESVMSELAK
     PELVEILMPA LIERWNKVSD QSRELFPLLE CLGYIASAYG DAFSPFAPPI FARCIKILYE
     NIQEYINAVN NATGDEPDKD FLVTSLDLLS CIIQAIDPQK SGELVANSQP RFFDLLCYCL
     QDPNGEVRLS SYALLGDCAI NLFPHLQPFL PTIMPVLIKQ LDLDLIRDDD SASGLSVINN
     ACWACGEIAI HAKAAMAPYV ESLYQAFAII MSNEEVPDSV NENAAIALGR LGSGCPEQLA
     PHLARFAEMF LRAMSKVEFT REKSSSFLGF NQVVQQNPKA MESCLGEYFH AIALFPMKSL
     SQPEFTSLQH SFQQVLQGYK SLIPDFNAFL SSLPVNVTRK LQSSYQL
//