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Database: UniProt
Entry: A0A0J8RB76_COCIT
LinkDB: A0A0J8RB76_COCIT
Original site: A0A0J8RB76_COCIT 
ID   A0A0J8RB76_COCIT        Unreviewed;      1504 AA.
AC   A0A0J8RB76;
DT   14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2015, sequence version 1.
DT   03-JUL-2019, entry version 21.
DE   SubName: Full=DNA polymerase zeta catalytic subunit {ECO:0000313|EMBL:KMU81655.1};
GN   ORFNames=CISG_02673 {ECO:0000313|EMBL:KMU81655.1};
OS   Coccidioides immitis RMSCC 3703.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenales incertae sedis; Coccidioides.
OX   NCBI_TaxID=454286 {ECO:0000313|EMBL:KMU81655.1, ECO:0000313|Proteomes:UP000054559};
RN   [1] {ECO:0000313|Proteomes:UP000054559}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RMSCC 3703 {ECO:0000313|Proteomes:UP000054559};
RX   PubMed=20516208; DOI=10.1101/gr.103911.109;
RA   Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA   Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA   Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA   FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA   Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA   Taylor J.W., Rounsley S.D.;
RT   "Population genomic sequencing of Coccidioides fungi reveals recent
RT   hybridization and transposon control.";
RL   Genome Res. 20:938-946(2010).
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DR   EMBL; DS268126; KMU81655.1; -; Genomic_DNA.
DR   EnsemblFungi; KMU81655; KMU81655; CISG_02673.
DR   Proteomes; UP000054559; Unassembled WGS sequence.
DR   GO; GO:0016035; C:zeta DNA polymerase complex; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0019985; P:translesion synthesis; IEA:InterPro.
DR   Gene3D; 1.10.132.60; -; 1.
DR   Gene3D; 3.30.420.10; -; 1.
DR   Gene3D; 3.90.1600.10; -; 1.
DR   InterPro; IPR006172; DNA-dir_DNA_pol_B.
DR   InterPro; IPR006133; DNA-dir_DNA_pol_B_exonuc.
DR   InterPro; IPR006134; DNA-dir_DNA_pol_B_multi_dom.
DR   InterPro; IPR042087; DNA_pol_B_C.
DR   InterPro; IPR023211; DNA_pol_palm_dom_sf.
DR   InterPro; IPR030559; PolZ_Rev3.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR025687; Znf-C4pol.
DR   PANTHER; PTHR45812; PTHR45812; 2.
DR   Pfam; PF00136; DNA_pol_B; 2.
DR   Pfam; PF03104; DNA_pol_B_exo1; 2.
DR   Pfam; PF14260; zf-C4pol; 1.
DR   SMART; SM00486; POLBc; 1.
DR   SUPFAM; SSF53098; SSF53098; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000054559};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054559}.
FT   DOMAIN       57    200       DNA_pol_B_exo1. {ECO:0000259|Pfam:
FT                                PF03104}.
FT   DOMAIN      834   1025       DNA_pol_B_exo1. {ECO:0000259|Pfam:
FT                                PF03104}.
FT   DOMAIN     1092   1178       DNA_pol_B. {ECO:0000259|Pfam:PF00136}.
FT   DOMAIN     1212   1355       DNA_pol_B. {ECO:0000259|Pfam:PF00136}.
FT   DOMAIN     1401   1472       zf-C4pol. {ECO:0000259|Pfam:PF14260}.
FT   REGION      414    463       Disordered. {ECO:0000256|MobiDB-lite:
FT                                A0A0J8RB76}.
FT   REGION      509    649       Disordered. {ECO:0000256|MobiDB-lite:
FT                                A0A0J8RB76}.
FT   COMPBIAS    414    434       Polar. {ECO:0000256|MobiDB-lite:
FT                                A0A0J8RB76}.
FT   COMPBIAS    435    463       Polyampholyte. {ECO:0000256|MobiDB-lite:
FT                                A0A0J8RB76}.
FT   COMPBIAS    509    523       Polar. {ECO:0000256|MobiDB-lite:
FT                                A0A0J8RB76}.
FT   COMPBIAS    537    551       Polar. {ECO:0000256|MobiDB-lite:
FT                                A0A0J8RB76}.
FT   COMPBIAS    567    585       Polar. {ECO:0000256|MobiDB-lite:
FT                                A0A0J8RB76}.
FT   COMPBIAS    598    620       Polar. {ECO:0000256|MobiDB-lite:
FT                                A0A0J8RB76}.
FT   COMPBIAS    628    649       Polar. {ECO:0000256|MobiDB-lite:
FT                                A0A0J8RB76}.
SQ   SEQUENCE   1504 AA;  170285 MW;  4E987794B27C04DD CRC64;
     MANSPYHPME PFRVLLNCVD HYQAAPTCLD PQLPCGDGPT SARTRPKVPV IRVFGATETG
     QKVCAHIHGA FPYLYIEYRG SLAMEQVKAA TRSLHVSIDH ALAVSYRRNA YDPGTAYVAH
     ISLVKGTPFY GYHVGHKFFF KIYLLNPLHM TRLADLLLQG AVMKRVLQPY ESHMQYIPQW
     MCDYNLYGCA YIDCRKVTFR GPVPLQCELE DSEHQWHDQN IAPALISDAG AFPRQSHCAL
     EVDVHVQDIL NRLGIKERPL HNYLFEGLDT IPPDAKLVPS LASLWEDEKR RRKAAMGLTD
     SESSPFTSAD LVSMSADSRN VAAGGWIHEE EFRARVAEIV VKEQARNNGA KPSPASLIQS
     DPFEASIQSA LDSVEDLYPE KLQAAVFDPV NVGDEGVEVG IEVDEARILS LQLPDTSNSY
     EDSSGSGLRT PQPDSTRETR IRGDLANVRT PRENRERLDE ENNTLDSSAH ITDAELTSMG
     VRRSSAIINS QEDFFEIDDE FISKIGSNRT KRSISTAANT QPSKRPRFML DPVKSSSILK
     SPRNEMTLSQ RPADQVERKW HIAAEELSSQ PKSSQKSNKS DGNSRLQFPV VKDPNDPATI
     SRASQQSGSV KLSHPISGFG SKSALTALPA PHSHSNSDKT TSCETSQLPR SDGVEFDKIL
     RESFNIPPNA TIYTFHSPCP SSSLIRETIS NDSRPSVVYQ DAYYSNDDDV PDRSREYAGR
     EFKLESNTVP YLPPFDPTGK SPLLHGDKRP VVVDQGALER ESDRLRKACS LRCWEFAPLP
     PSRSEVIEWC KEQDSKRLGP QSFTTTNSKQ PGISQIEAAT QKDSHGFLYS QKKFSRNIQH
     EAHYMSVMSL EVHVNTRCTL APNPEEDEIS CIFWCIQSGD RSLGVNEPSD EVQTGVLAVA
     ETESIAAKIR YDTNAEIEEE SSELDVLTKL VDIVRYYDPD ILTGYEVHNG SWGYLIERAR
     VKYDYDLCDE LSRVKTDSHG RFGKESDRWG FNHTSTIRVT GRHMINIWRA MRSELNLIQY
     TLENVAFHLL HKRIPHYPFH DLTKWFKSTK PRNLVKVVNY FITRTRLNLD ILDANELISR
     TSEQARILGI DFFSVFSRGS QFKVESLMFR IAKPENFILI SPSKAQVGQQ NALECLPLVM
     EPQSDFYNSP LLVLDFQSLY PSVMIAYNYC YSTFLGRIVD WRGRNKMGFI DYQRQPGLLG
     LLESQINIAP NETVRRDGTP AEQKIEEKAL RILFETADLS RVKKYFQKQC AKIMQGKVSI
     QDFCFAKEVR LGTYSEKGPP PPGALISAKR MLEDPRLEPQ YGERIPYVVI SGAPGSRLID
     RCVAPEVLLQ DPQMELDAEY YISKNLIPPL ERIFNLVGAN IRQWYDEMPK YQRVRRTDNA
     MISDGTLLRK TLESYMRASS CVVCREKLEN GEALCNHCLR RPHLSLMRLR YRVQRAEKKV
     ANIHEVCRSC MGVQWGEEVK CDSKDCPVFY SRTRTTFNLS YTRSLSDPIA EALERSGESN
     PWAW
//
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