ID A0A0J8RKX6_COCIT Unreviewed; 778 AA.
AC A0A0J8RKX6;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Rad4 {ECO:0000313|EMBL:KMU85790.1};
GN ORFNames=CIHG_03318 {ECO:0000313|EMBL:KMU85790.1};
OS Coccidioides immitis H538.4.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=396776 {ECO:0000313|EMBL:KMU85790.1, ECO:0000313|Proteomes:UP000054563};
RN [1] {ECO:0000313|Proteomes:UP000054563}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H538.4 {ECO:0000313|Proteomes:UP000054563};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; DS016990; KMU85790.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0J8RKX6; -.
DR STRING; 396776.A0A0J8RKX6; -.
DR VEuPathDB; FungiDB:CIHG_03318; -.
DR eggNOG; KOG0987; Eukaryota.
DR eggNOG; KOG1929; Eukaryota.
DR Proteomes; UP000054563; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:UniProt.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR CDD; cd18433; BRCT_Rad4_rpt3; 1.
DR CDD; cd17723; BRCT_Rad4_rpt4; 1.
DR CDD; cd17731; BRCT_TopBP1_rpt2_like; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 4.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR PANTHER; PTHR13561; DNA REPLICATION REGULATOR DPB11-RELATED; 1.
DR PANTHER; PTHR13561:SF20; DNA TOPOISOMERASE 2-BINDING PROTEIN 1; 1.
DR Pfam; PF00533; BRCT; 1.
DR Pfam; PF12738; PTCB-BRCT; 2.
DR SMART; SM00292; BRCT; 3.
DR SUPFAM; SSF52113; BRCT domain; 4.
DR PROSITE; PS50172; BRCT; 4.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000054563}.
FT DOMAIN 8..81
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 103..192
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 271..371
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 383..468
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT REGION 470..609
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 637..665
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 722..778
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 474..508
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 509..523
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 554..577
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 640..665
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 722..740
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 778 AA; 86242 MW; 41C54E7E678DB9D1 CRC64;
MAEDVAPNKE QPLRGVILCC TSILPETRSQ LAAIAGQMGA VHMFDLTSDV THLIVGETNT
PKYKYVAKER SDVKVLRPEW IEAVRSSWLL GGDTDLHALE EEYKLPTFTG LSICLTGFED
LNFRNHLQRT IAKNGGEFRR DLTKSVTHLI ARSAEGQKYK FGVLWNIKIV GLRWLEDSLE
RGMVLDESLY DPLVPEEEQG IGAWNRTAPI QVEKRQNVAE VHSVLETRRV TSVNCDQTKD
MTEIWETIPP AATNRAFTMD ALAPRFQPAE KARGIWYGAQ FFISGFTTKQ TQLLRNHLIS
RDAEIVSSID DLSIGDGGPD PKQYILVPYN LPQSDIPSTA DSESEVHVVT DMWIEKCIHS
NTFVPPEAHT TSTPVPRFPI PAFQSLRVCS TGFTGIDLLH VSKLVTLLGA TYDEYFTQKA
SVLICNTTKP NSEKLRHAQQ WNIPAVLADW LWISVQTGEM KAFEPYLISG RDPYSAGGQT
NETRSLGGSR QTEPKKLQGP SGQQPESRRQ DEGSSKEEPI LTHDASLEPG SHGSPAKKMP
SPPPTLALPK TDSSEDKPAT SSRSLDVAIS ELLRQTRSRA KQSAEKSAHT QRRRRLFGRA
NSNSSLLGNK ERISRASSID TLNEDGYGSV VDGFNSPSVK GHSKAPSFTS LAQPTAALKG
NSDPTEAQQL LESRLNLLRN GLGQYDAERY EFEEEETPPM TQLGYEAPDA VAMREKITRR
AREMNGAEEN TDDMQEGKNK NDNGGRLVLG QLKDSETLAI WGGGRRTRSK RTSNGDEV
//
