ID A0A0J8RRS1_COCIT Unreviewed; 562 AA.
AC A0A0J8RRS1;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 28-JUN-2023, entry version 31.
DE SubName: Full=Kinase C {ECO:0000313|EMBL:KMU87945.1};
GN ORFNames=CIHG_05712 {ECO:0000313|EMBL:KMU87945.1};
OS Coccidioides immitis H538.4.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=396776 {ECO:0000313|EMBL:KMU87945.1, ECO:0000313|Proteomes:UP000054563};
RN [1] {ECO:0000313|Proteomes:UP000054563}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H538.4 {ECO:0000313|Proteomes:UP000054563};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
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DR EMBL; DS017001; KMU87945.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0J8RRS1; -.
DR STRING; 396776.A0A0J8RRS1; -.
DR VEuPathDB; FungiDB:CIHG_05712; -.
DR Proteomes; UP000054563; Unassembled WGS sequence.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd08689; C2_fungal_Pkc1p; 1.
DR CDD; cd11621; HR1_PKC-like_1_fungi; 1.
DR Gene3D; 3.30.60.20; -; 1.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR InterPro; IPR046349; C1-like_sf.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR037778; C2_fungal_PKC.
DR InterPro; IPR011072; HR1_rho-bd.
DR Pfam; PF00168; C2; 1.
DR Pfam; PF02185; HR1; 1.
DR SMART; SM00239; C2; 1.
DR SMART; SM00742; Hr1; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR SUPFAM; SSF57889; Cysteine-rich domain; 1.
DR PROSITE; PS50004; C2; 1.
DR PROSITE; PS51860; REM_1; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01207};
KW Kinase {ECO:0000313|EMBL:KMU87945.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054563};
KW Transferase {ECO:0000313|EMBL:KMU87945.1}.
FT DOMAIN 142..219
FT /note="REM-1"
FT /evidence="ECO:0000259|PROSITE:PS51860"
FT DOMAIN 302..420
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT REGION 219..282
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 562 AA; 62634 MW; C15BE6CA4F06F7DC CRC64;
MSLRSNPFAG SSTEDSPSAM RMNRAKLLQL VDTTAADSFF IDVKPGLQES SSGQDLDWRV
CEKFIPTIAS GSFSSFPSLT DKLGIPHAAQ STVVYFANFD ILRNWGFIRL PVVGNWALAL
PHECDQSFIS FNHCVDHSQP KSGLCKGATA KMDGDDELMA KVYRKIEREK ALINAATNMR
QSTDNPLVQQ RVDANIRDGR KNIAYLEEKM RELQLRKMGR EAGQQPGSPT QQRHSGGAPP
PPPKDGGHYS SDIGYAQEGS GSMPSQAPFH DPRPGGPIPK ARPNFSKLVC AISIRVLTTP
SPTADESLSS PNIRKPLTGH LTMRIHAVRD VDHAAGSRFS RGPETFVIMK VEDAIKAKTK
ATRNDKWAEE TFNVDIDKAN EIELTVYDKS GDRPTPIGML WIRLSDIAEE MRRKKIETEF
NTSGWVSADK MEHGAARTES HFQVNAPQHP QHDQASQPGP GATVMIDSWF ALEPVGRIHL
TMSFAKQLKD RRPFDIGLNR QGAVRQKKEE VHEKQGHKFV TQQFYNIMRC ALCGDFLKYA
AEMLPQGGHE VYQQSQLRDR SR
//
