ID A0A0J8RVJ6_COCIT Unreviewed; 452 AA.
AC A0A0J8RVJ6;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Metacaspase {ECO:0000313|EMBL:KMU88591.1};
GN ORFNames=CIHG_06529 {ECO:0000313|EMBL:KMU88591.1};
OS Coccidioides immitis H538.4.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=396776 {ECO:0000313|EMBL:KMU88591.1, ECO:0000313|Proteomes:UP000054563};
RN [1] {ECO:0000313|Proteomes:UP000054563}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H538.4 {ECO:0000313|Proteomes:UP000054563};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
CC -!- SIMILARITY: Belongs to the peptidase C14B family.
CC {ECO:0000256|ARBA:ARBA00009005}.
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DR EMBL; DS017006; KMU88591.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0J8RVJ6; -.
DR STRING; 396776.A0A0J8RVJ6; -.
DR VEuPathDB; FungiDB:CIHG_06529; -.
DR Proteomes; UP000054563; Unassembled WGS sequence.
DR GO; GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.40.50.12660; -; 1.
DR InterPro; IPR011600; Pept_C14_caspase.
DR PANTHER; PTHR48104:SF30; METACASPASE-1; 1.
DR PANTHER; PTHR48104; METACASPASE-4; 1.
DR Pfam; PF00656; Peptidase_C14; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000054563}.
FT DOMAIN 174..442
FT /note="Peptidase C14 caspase"
FT /evidence="ECO:0000259|Pfam:PF00656"
FT REGION 1..156
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..21
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 34..112
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 452 AA; 49302 MW; B8BCC51D815FEF62 CRC64;
MSYYPPPSGY PGGPPAYPPP QQQQQQQQQY PSYGAPPPQY PPQNNYAPPS YPPPGQYGHP
PQPGYPPHSS PYGHTPSPQP PYGNLQHPPP QHPPHQPPHR PPPSPGYGHL PPSTPNSGPA
FHGQPGIATV NNNDYVHGNH SAPPPPPSGS VAFGHGAPQG YSYQDASYGA VFDDVKNMSK
YLNQSFKYAR EDMVILTDDQ QNPMSQPTKV NIERGMHWLR KMLDRPTHCL PLLCGAKTYF
VGHGGQTPDL DGDEDDGYDE VIYPVDFRNA GHIVDDEMHR IMVRPLPAGV RLTAIFDSCH
SGSALDLPYI YSTQGVLKEP NLAKEAGQGL LGVVSAYARG DMGSMVSTAM GFIKKATRGE
ETYQRAKQTK TSPADVIMWS GSKDVQTSAD ATINGQATGA LSWAFITALK KNPQQSYVQL
LNSIRDELAS KYSQKPQLSC SHPLEYDSYA QL
//
