ID A0A0J8S1Y2_COCIT Unreviewed; 1840 AA.
AC A0A0J8S1Y2;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=Transport protein sec71 {ECO:0000313|EMBL:KMU91152.1};
GN ORFNames=CIHG_08901 {ECO:0000313|EMBL:KMU91152.1};
OS Coccidioides immitis H538.4.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=396776 {ECO:0000313|EMBL:KMU91152.1, ECO:0000313|Proteomes:UP000054563};
RN [1] {ECO:0000313|Proteomes:UP000054563}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H538.4 {ECO:0000313|Proteomes:UP000054563};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
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DR EMBL; DS017031; KMU91152.1; -; Genomic_DNA.
DR STRING; 396776.A0A0J8S1Y2; -.
DR VEuPathDB; FungiDB:CIHG_08901; -.
DR eggNOG; KOG0929; Eukaryota.
DR Proteomes; UP000054563; Unassembled WGS sequence.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProt.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR CDD; cd00171; Sec7; 1.
DR Gene3D; 1.10.220.20; -; 1.
DR Gene3D; 1.10.1000.11; Arf Nucleotide-binding Site Opener,domain 2; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR032629; DCB_dom.
DR InterPro; IPR015403; Mon2/Sec7/BIG1-like_HDS.
DR InterPro; IPR032691; Mon2/Sec7/BIG1-like_HUS.
DR InterPro; IPR046455; Sec7/BIG1-like_C.
DR InterPro; IPR023394; Sec7_C_sf.
DR InterPro; IPR000904; Sec7_dom.
DR InterPro; IPR035999; Sec7_dom_sf.
DR PANTHER; PTHR10663; GUANYL-NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR10663:SF375; LD29171P; 1.
DR Pfam; PF20252; BIG2_C; 1.
DR Pfam; PF16213; DCB; 1.
DR Pfam; PF01369; Sec7; 1.
DR Pfam; PF09324; Sec7-like_HDS; 1.
DR Pfam; PF12783; Sec7-like_HUS; 1.
DR SMART; SM00222; Sec7; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF48425; Sec7 domain; 1.
DR PROSITE; PS50190; SEC7; 1.
PE 4: Predicted;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000054563};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 777..975
FT /note="SEC7"
FT /evidence="ECO:0000259|PROSITE:PS50190"
FT REGION 1..142
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 341..409
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 742..782
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1135..1165
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1320..1342
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1555..1595
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 17..34
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 41..75
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 383..397
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 742..771
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1324..1342
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1574..1595
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1840 AA; 206468 MW; B9E85E23FCAA5D82 CRC64;
MAQCDVPEHD FVTGTSLSDE PAGSPTNNEA TMAELNETDP VPHTTELSTS ASQEVPSQNE
PSNTQESTND AVQGTGKESG DPAVPQENIG EEGPSIPVIT SSDTAMEADK RNQSHPSPIP
ALPAETRERS DSRSTVATQG MHRSAPLTSA VFVITALDTI AASKEARRSK ELGEAVSLAQ
GNIKQSEQHP IDPEIIFRPL ELASKTVSIP LQITALDCIG KLITYSYFAF PSSPDEPSSE
SQNQPPLIER AIETICDCFE NEATPPEIQQ QIIKSLLAAV LNDKIVVHGA GLLKAVRQIY
NIFIYSKSSQ NQHIAQGSLT QMVGTVYDRV RLRLDLKEAR LRDAQSQRNR SESDASLDQP
NDDASNEQDE SPEDGQSLVS DHPVAKEPRE KMTLQSFETN KDDAMVNDNA PTMVTRAKAN
RKASRSVPGE DLDPATDDED EIYVKDAFLV FRALCKLSHK ILSHEQQQDL KSQNMRSKLL
SLHLMQHLLS NHVTVFTSPL ATIRSSSNTG DTMTLLQAIR PHLCLSLSRN GASSVPPVFE
VCCEIFWLML RHMRVMLKVS PKMLLNKELE VFFKEIYLAI LEKRNSPMFQ KKYFMDILGR
LSTDPRALVE LYLNYDCDRM ALENTFQGII EQLSRISSMP VAVTVQQQQQ YQEHRANTPT
SAHDWHQPGT LPPSLSTAKI DNIAPTSSQN IPPEYAMKQR ALECLVEILR SLDTWSSQDT
NSSKSLPREP FSRNSLAMSR ESLDTAAPTL STASPRVDSG EPLTGQSTPV AEDDPNEIEK
AKQQKIALTN AIRQFNFKPK RGMKLFLSEG FIRSDSPSDI ASFLLRNERL DKAAVGEFLG
EGDAENIAIM HAFVDLMDFG DRGFVDALRE FLQSFRLPGE SQKIDRFMLK FAERYLTGNP
KSFATADDPY VLAYSVIMLN TDLHSSKLKR KMTKEDFIRN NRDLQDVPQE YLGATVGRDI
QGEKYAQASE EIANKTEQLY RSLIRAQRKS AMKEALSRFI PATSVRHVGS MFNVTWMSFL
SGLSAQVQDT QNLDTIRQCM EGIRLAIRIS CAFDLETPRV AFVTALAKFT NLGNLREMMA
KNLEALKVLL DVAISEGNHL KSSWREILTC ISQLDRFQLL TDGVDEGALP DMSVARVVPP
SDSSRTRKSL QVPRRPRPRS INGSTQFRPD IAMESRSTEM LSMRFLEIEE LPGFKFQKDF
LKPFEHVMAN STVVTVKDMV LRCLIQMIQA RGNNIRSGWK TMFGVFSVAA REPYEGIVNM
AFEHVSQIYN TRFGVIITQG AFPDLVVCLT EFSKNLKFQK KSLQAIETLK STVPKMLKTP
ECPLSHRRSS TSSAPSDTVV PLTPQTSRQS AEEQFWYPVL IAFQDVLMTG DDLEVRSRAL
TYLFEILIRY GGDFPTEFWD VLWRQLLYPI FVVLQSKSEM SKVPNHEELS VWLSTTMIQA
LRHMITLFTH YFDALEYMLD RFLGLLTLCI CQENDTIARI GSNCLQQLIL QNVQKFQATH
WDKIVGAFVE LFEKTTAYEL FTAVIPNPAK SSESSKVADD SASVNEISNE QIAVGDETSI
NGDQRPATAT EAEEAKSPQH SAQLEDHASP TEQQQAPLAI SASRRKFFNR IITNCVLQLL
MIETVNELFS NDAVYEQIPS DELLRLMALL KKSYQFAKKF NEAKDLRVAL WKQGFMKQPP
NLLKQESGSA ATYVNILFRM YHDEGDERKS SRGETEEALI PLCADIIRGY VKLDEETQQR
NIAAWRPVVV DVVEGYTGFP RETFDKHVET FYPLGVELLS RDLNSEVRLA LQSLFRRVGE
CRLGMRPVSP VEAPMSPRGS VLHSYFGNGH RRSRGRSIKG
//
