ID A0A0J8S4P8_COCIT Unreviewed; 359 AA.
AC A0A0J8S4P8;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Ribosomal RNA-processing protein 43 {ECO:0000256|ARBA:ARBA00030617};
GN ORFNames=CIHG_09654 {ECO:0000313|EMBL:KMU91781.1};
OS Coccidioides immitis H538.4.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=396776 {ECO:0000313|EMBL:KMU91781.1, ECO:0000313|Proteomes:UP000054563};
RN [1] {ECO:0000313|Proteomes:UP000054563}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H538.4 {ECO:0000313|Proteomes:UP000054563};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the RNase PH family.
CC {ECO:0000256|ARBA:ARBA00006678}.
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DR EMBL; DS017043; KMU91781.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0J8S4P8; -.
DR STRING; 396776.A0A0J8S4P8; -.
DR VEuPathDB; FungiDB:CIHG_09654; -.
DR Proteomes; UP000054563; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0000176; C:nuclear exosome (RNase complex); IEA:UniProt.
DR Gene3D; 3.30.230.70; GHMP Kinase, N-terminal domain; 2.
DR InterPro; IPR001247; ExoRNase_PH_dom1.
DR InterPro; IPR036345; ExoRNase_PH_dom2_sf.
DR InterPro; IPR027408; PNPase/RNase_PH_dom_sf.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR PANTHER; PTHR11097:SF9; EXOSOME COMPLEX COMPONENT RRP43; 1.
DR PANTHER; PTHR11097; EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN; 1.
DR Pfam; PF01138; RNase_PH; 1.
DR SUPFAM; SSF55666; Ribonuclease PH domain 2-like; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000054563};
KW rRNA processing {ECO:0000256|ARBA:ARBA00022552}.
FT DOMAIN 58..247
FT /note="Exoribonuclease phosphorolytic"
FT /evidence="ECO:0000259|Pfam:PF01138"
FT REGION 105..133
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 265..284
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 359 AA; 39120 MW; 632DA26B2253B5C1 CRC64;
MTSTAPNTKA PATPSPFLSL SPAHLARLQP HTYVYAHLNP SPDISRPSIR INGRTESQFR
PASVNTGSLS HTNGSAVVRI GDTTAVCGVR GEILSTHDIP AWKVSNNGAG SSWGSPQKRN
QDHDAEDEDY DEDDSEIHAF NLLVPNLSLS TGCSPSILPG SAPSSLAQSL SHQLLSLLHS
SRLIRASDLR IWSNPNPTQA PSQEQSEDID MEDTPAFTDS VGAPELKAFW TLYIDVLIIS
HAGNSFAVFE ADPVGDWRKV IIPLQDGEPK EKDQTSADDG DAARRKRWIL ADPDAFEESL
CQERVCIVVD KDGKKPGCMK ILMMEKGGGF YVGKSEIKGL VELASVRWEE WRALLEGVR
//
