ID A0A0J8S5W5_COCIT Unreviewed; 2688 AA.
AC A0A0J8S5W5;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Midasin {ECO:0000313|EMBL:KMU92567.1};
GN ORFNames=CIHG_10391 {ECO:0000313|EMBL:KMU92567.1};
OS Coccidioides immitis H538.4.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=396776 {ECO:0000313|EMBL:KMU92567.1, ECO:0000313|Proteomes:UP000054563};
RN [1] {ECO:0000313|Proteomes:UP000054563}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H538.4 {ECO:0000313|Proteomes:UP000054563};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
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DR EMBL; DS017096; KMU92567.1; -; Genomic_DNA.
DR STRING; 396776.A0A0J8S5W5; -.
DR VEuPathDB; FungiDB:CIHG_10391; -.
DR eggNOG; KOG1808; Eukaryota.
DR Proteomes; UP000054563; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR040848; AAA_lid_7.
DR InterPro; IPR011704; ATPase_dyneun-rel_AAA.
DR InterPro; IPR048617; MDN1_AAA_lid_4.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR48103:SF2; MIDASIN; 1.
DR PANTHER; PTHR48103; MIDASIN-RELATED; 1.
DR Pfam; PF07728; AAA_5; 4.
DR Pfam; PF17867; AAA_lid_7; 1.
DR Pfam; PF21108; MDN1_4th; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 3.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000054563}.
FT DOMAIN 295..467
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 604..839
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 2519..2577
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2589..2688
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2520..2534
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2555..2577
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2607..2627
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2628..2656
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2663..2679
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2688 AA; 300488 MW; 78825CA3548495A0 CRC64;
MPTLGEPSLD DLNSALASVS PTKLEKCNQD TLNRIRHNLT RVNALFEWSD GSLVSAMKSG
QHFLLDELSL ADDSVLERLN SVLEPHRSLL LAEKGPIDSL VVAAPGFQFL GTMNPGGDYG
KRELSAALRN RLTEIWVKLH SSLQNIAKPM MEFAKWFKET FQGSTSGSNS VRDLLAWVNF
VNDCRNLQPG LAVVHGACLV YIDSLGANPS AILAVASGDL NKDRRRCLEK LELIFSFDAV
SMYFCETRLD IDEERMVIGP FELAVGSNSQ PDPTFALDAP TTLLNTLRVA RGLQSSRPIL
LEGSPGVGKT TLVAALARGL GKPLTRINLS EQTDLTDLFG SDIPVEGAEI GNFAWSDAPF
LRAMQQGGWV LLDEMNLASQ SVLEGLNSCL DHRQQVYIAE LDQTFKRHPD FVLFATQNPH
HQGGGRKGLP ASFVNRFTVV YADSFTTDDL KLICRRLSRR VPPDQVERMV EFISTLNIRL
LSDRRLGAIG GPWEMNLRDL SRWLMLSERF ELGDHPSQFL DIIVSQRFRT LEDRKVVSKL
YEEIFGTTPI SKSYFHNLRP DTYHIGIGTL QRDQILQHAS RRQIEILPRD LPILESLMLC
VEKRWPSVLV GPSGCGKSAT LQKLAALSGA RIVELALNAD TDAMDLIGGF EQRDDHRQIS
SLIDELAGLL QSCIIQAYSG TGSGGLDPEL TKLYKMINSD PLRLEDISDS LSRISNDHGN
PGLRELSHRC TQLVAGSSNE HIGFEWTPGL LIHAMQRGDW VVLDNANLCS ATVLDRLNSL
MEPDGYLIIN EQRTSDGSVQ IVKPHPHFRL FLTMDPKYGE LSRAMRNRSI EIFFLQQGDP
NPVPSSMITY SCDSAIYRLR NCHTFNSSEP SAVNDIAFEI SLDHLTPADI TEINTSLPSF
IQLWAGNKAL TESISLALNR YHSLVANNSL VGWPEYVLLS ELVDSTKFLQ PQQHTEPLHP
LINEPRLFHY PLISDHRSCL MRLAKLQEIQ LDTARLYQEL SRVGNIARSK KASDMNRLER
SMTSSTIAAH KKDSTVLVSY ESAPMHLMEL WSRMLDSFQA NWRLTTGQSM QMMWEAWRPA
TASDPVSLQQ MMKLEQLCSR FDEMVQKTNL SLTERSQLSN SLAGAKSSLL LGADGSRLVD
DLTFAINELA KRLHDTKSIV SPYFSAEYEA LCQYHDLSGW HSIEDAGSLQ GVLKLLAGRP
SSPSDISPFG NAAPGLLSDI SRFAGFRSPL NTAFALKGTI SLSLIQKLKQ IGNVPLSQMD
LLHTELAFLS KALASSAVEI SRDQFALLTS HLKELLKGYL VCHRNLIAPQ SLDAVITGLD
GDRKLSLPLN GLEADVIEPA AHKDAAHGSF VIKTVCDCFH DLITDQGVSN PYLQHGKALI
RFAMALLRSF IPDRPFDPSL AVVVERERYG KRMLERTQRL QAVKAFETRY SGQSTSLRIR
VLEDELRSLG KEPSQPSVSR PKPSRLSALQ GEFMNIVTSI LSKSVEDIFV SCQSLGGQSG
PHLIQQNIRQ MCARLERNYR AYDDITVPVV RFLELLDLGI GLFQYSQVGP TDQQSFVRDI
SQATPFLGQA RTSARLLRTI GAPHLARLNL ETDLYRLSVI SASQNTDSRT LHDVDYREIL
RSSLQHLYMQ WKEQLQADQV KEAERSALFR YRGSVEDQDE IDAEELLHMF PTFDEEPKAQ
GESLAKFDNK GVASKLSKLF KELFTTGDRE LEIKGLIAKA TELIGSILPG DELSVPLVQP
QNHLSAVLLL LEDEVHTSPM SSYNFYTDPN LPEVKKLADL VERTQRRFYE LQRSWPEHAT
LADAITCCSE IYQFKHCEPV AKFLTKAEKL HGYIHEWQTV ASKEFSAANF YDELTALLIS
WRRLELSTWA RLLDIEYEKC EQDADGWWFV AYEVIVATPL QLIQEGQDLV SHTCELISTL
EKFICSTPIG QYRSRLQLVE RFNSLLQLYA IDFPSLRRVI SALANLINHY KPFVQIFEEQ
LSNGRKSLET DIKQEILLTS WKDTNITALR ESARRSHYKL FKVVRKYRAI LGQLSDSTIE
NGLPTSAYKS EPAVVSSLHK PEAVSSTALS ICQEVISTWG SRPARFKDID ATTGNMRHVY
QRCFADFSVP CELDAFIRDV IDSINDFKSK TPKTLTEENK EEVQHLKVQK RRFYAEKLRE
LRHMGIRSNL GTDILEKQSP APRQAAREYS EDLSNVEAGR SAGFVEGILS RARTERTTIY
PALTALDSLT TVIQEMDSLS CLSKGSLRVN AAMAVHVKDL QGTLRWLSAL LETSVAILNI
HARHTNTDLS RVLNELSSRK DQAEGSYLAL ESLATLPKGL SSDVHEDQIL QAQTLITQIQ
TDVIRLGQTH PDVAFAMDQI LPWTKIDLSE YPNPKDGRYS ALLLKDIDKS LLSVIDKVFV
VLQRLSNCLS SYPASTENTG WLAKTDSVLS KALEELHMEE IANSMSSVLN TIRLISMQTP
NELDTVIAII SSLLPIMHQY RYICVDLVHR YANLHREVCK MGYVLSNSFI RVASEGFCSP
TEASDEQGSS GKLENGTGLG DGGGAEDISK DVQDDEDLSD LAQQKSENHG EKDDIEAADD
AVNMDNEDLE ADAEDFEQKE KGQQDEDESD LESADNMDEE VGSVDGWDQD AVDEKLWDGK
NNPDQKDTEN EEGKGSSNTD EQAAAPEKKD SKANEAEDPE AGSDNENP
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