ID A0A0J8TI24_COCIT Unreviewed; 1011 AA.
AC A0A0J8TI24;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Carrier domain-containing protein {ECO:0000259|PROSITE:PS50075};
GN ORFNames=CISG_03517 {ECO:0000313|EMBL:KMU73382.1};
OS Coccidioides immitis RMSCC 3703.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=454286 {ECO:0000313|EMBL:KMU73382.1, ECO:0000313|Proteomes:UP000054559};
RN [1] {ECO:0000313|Proteomes:UP000054559}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RMSCC 3703 {ECO:0000313|Proteomes:UP000054559};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
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DR EMBL; DS268130; KMU73382.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0J8TI24; -.
DR STRING; 454286.A0A0J8TI24; -.
DR Proteomes; UP000054559; Unassembled WGS sequence.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0044550; P:secondary metabolite biosynthetic process; IEA:UniProt.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR013120; Far_NAD-bd.
DR InterPro; IPR013217; Methyltransf_12.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR45681:SF6; CARRIER DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45681; POLYKETIDE SYNTHASE 44-RELATED; 1.
DR Pfam; PF18558; HTH_51; 1.
DR Pfam; PF08242; Methyltransf_12; 1.
DR Pfam; PF07993; NAD_binding_4; 1.
DR Pfam; PF00550; PP-binding; 1.
DR SMART; SM00823; PKS_PP; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000054559};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 72..146
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT REGION 152..190
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 170..189
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1011 AA; 112574 MW; 98B70BA15B746A70 CRC64;
MPAAGALVEA ILGISYVRIP KVSMSKLLSC LTVRNAHGCV AKHSGQSRVH HIGQPRTKYH
QTGKGEEAVS ESRREPEVKA ILVELSGLEL DEIKDDSQLA DLGIDSLMGM EMAHEIEQAF
NITLPESELM QIVDMCNLLK CVQSAVNRST GGEVAANSDY GESDDSYERS NTNNEFTAST
IQTNPSTPVP EAERDLLNKE PTGLELPFAT VMEAFNETKQ LTDEKIAEYN QTNYVDMVMP
VQTQLCIALT LEAFDELGCN LREAKPGQKL ARISHPSEHR RLVDYLYRML AKEALLINLD
GDTITRTTTP PPPESSKDIL EQLLKRFPDQ NTADRLTFYT GSNLAEVLRG NTDGIKLIFC
TEEGRELVSG LYADWPLNRL FYAQMEDFLC RLISKLDMST GPLKILEMGA GTGGTTKWIV
PLLAKLNVPI EYTFTDLAPS FVAGARKKFK PYQFMKFRTH DIEKAPADDL IGTQHVVIAS
NAVHATHSLC ESAKNIRKAL RPDGLLMMLE MTGTLYWVDM IFGLFEGWWF FDDGRTHAVT
CESRWEKDLQ SVGYGHVDWT DGNMPENKVE KLIIAMASGS RCDRLRIPST PKPIEIRSAD
CAARQAVVNK YVQELTDGFA AAVVDELSAS LPKHNPKGKT VLVTGATGSL GSHIIAKLAN
LPDIRRVVCL NRRSRQVPKE RQQQALTKKG ISINPEASRK LCVIETDLSK PNLGLLTVDY
EDLVNNVTDI IHNAWLMKCP SGPVKNFYTP ASDYVPTCSI SLGTKVTFEF ISSIATVGHW
PIWTGKVNVP EERMTIESVL PTGYGDAKYI CECMLDETLH KYPDRFRATA IRLGQVGGSS
ASGYWNPMEH LSFVFKSSQT LQALPDFDGL LSWTPVDDVA STLVDILMLP EETTLYPIYH
IDNPVRQPWK EMIPVLADAR DIPPQNVIPF KDWVQRVIDH PRRVEGPEAK NPAIILIDFL
DGNFLRMSCG GLLLDTAKAR EHSRTLANVG PVSERVARLF VKSWKDMGFL N
//
