ID   A0A0J8TPM3_COCIT        Unreviewed;       273 AA.
AC   A0A0J8TPM3;
DT   14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT   14-OCT-2015, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   SubName: Full=FHA-HIT protein {ECO:0000313|EMBL:KMU75662.1};
GN   ORFNames=CISG_04836 {ECO:0000313|EMBL:KMU75662.1};
OS   Coccidioides immitis RMSCC 3703.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX   NCBI_TaxID=454286 {ECO:0000313|EMBL:KMU75662.1, ECO:0000313|Proteomes:UP000054559};
RN   [1] {ECO:0000313|Proteomes:UP000054559}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RMSCC 3703 {ECO:0000313|Proteomes:UP000054559};
RX   PubMed=20516208; DOI=10.1101/gr.103911.109;
RA   Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA   Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA   Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA   FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA   Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA   Taylor J.W., Rounsley S.D.;
RT   "Population genomic sequencing of Coccidioides fungi reveals recent
RT   hybridization and transposon control.";
RL   Genome Res. 20:938-946(2010).
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DR   EMBL; DS268142; KMU75662.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0J8TPM3; -.
DR   STRING; 454286.A0A0J8TPM3; -.
DR   Proteomes; UP000054559; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006139; P:nucleobase-containing compound metabolic process; IEA:UniProt.
DR   Gene3D; 3.30.428.10; HIT-like; 1.
DR   InterPro; IPR011146; HIT-like.
DR   InterPro; IPR036265; HIT-like_sf.
DR   InterPro; IPR032566; Znf-C2HE.
DR   PANTHER; PTHR12486:SF4; APRATAXIN; 1.
DR   PANTHER; PTHR12486; APRATAXIN-RELATED; 1.
DR   Pfam; PF01230; HIT; 1.
DR   Pfam; PF16278; zf-C2HE; 1.
DR   SUPFAM; SSF54197; HIT-like; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054559};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          70..197
FT                   /note="HIT"
FT                   /evidence="ECO:0000259|Pfam:PF01230"
FT   DOMAIN          212..268
FT                   /note="Aprataxin C2HE/C2H2/C2HC zinc finger"
FT                   /evidence="ECO:0000259|Pfam:PF16278"
FT   REGION          1..53
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        22..39
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   273 AA;  31371 MW;  5F0CAE7A394E6E52 CRC64;
     MPATPQTSEK DAERAASPEM AGKTTNAFTV LMSKKPKDST NSPELSRDRT KFPRAFHSRD
     ALGAYIERPE SSPGIVYHTD DFVAISDLYP KASIHLLLLP RDPSKYRLHP FDAFEDHEFL
     TKVQAEAQKL RKTAASELRR RYGKYSVSEK ARSEAMDADP APDELPPGRD WEKEIMCGVH
     AHPSMNHLHV HIISKDRCSP CLKHRKHYNS FSTPFFVPID DLPLDHHDAR RHPGREGYLQ
     QDLKCWRCGS NFGNKFTLLK DHLNQEFETW KCY
//