ID A0A0J8UAC7_COCIT Unreviewed; 622 AA.
AC A0A0J8UAC7;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Acyl-CoA synthetases /AMP-acid ligases II {ECO:0000313|EMBL:KMU84053.1};
GN ORFNames=CIHG_01839 {ECO:0000313|EMBL:KMU84053.1};
OS Coccidioides immitis H538.4.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=396776 {ECO:0000313|EMBL:KMU84053.1, ECO:0000313|Proteomes:UP000054563};
RN [1] {ECO:0000313|Proteomes:UP000054563}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H538.4 {ECO:0000313|Proteomes:UP000054563};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
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DR EMBL; DS016984; KMU84053.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0J8UAC7; -.
DR STRING; 396776.A0A0J8UAC7; -.
DR VEuPathDB; FungiDB:CIHG_01839; -.
DR eggNOG; KOG1176; Eukaryota.
DR Proteomes; UP000054563; Unassembled WGS sequence.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR CDD; cd05941; MCS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43201; ACYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR43201:SF8; FATTY ACID COA SYNTHETASE FAMILY; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:KMU84053.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054563}.
FT DOMAIN 95..448
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 518..607
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 622 AA; 67592 MW; A7802698B989B269 CRC64;
MLSYPGPLVA RCRESQLRSI LYSATSIRVP TPRTRRELST LPDLPLFRAL ASHDPKSTSI
VHSVSGRTFN YGNLLGDTLR AQEKLLQIAG RNPAVGGMQG RPVAFLAENS YDYVGIVCLT
VTLLSVLALD GIALPLSPAF PVGELRYILD NSQAGILLAT GKYASKAKEV VEGDLENVPV
VEIIDKINVG GGTVSELQFE NRSQNGGMML YTSGTTNRPK GVLLPQSALM AQTQSLVEAW
EYSPRDRLLH LLPLHHIHGT VNAILAPLLA GSSIEFMFPF NPTAVWNRFA ASFLRSQCGS
QAGNTAPITF FTAVPTIYNR LLSTHATLPP ETQEAAKVAI SPRHLRLNIS GSAALPTPTK
SAWTNLSGGN ILLERYGMTE VGMALSCSLD FADRVDGSVG WPLPSVQARL VDTDTNEVIQ
PGEEIDQDGR LRVGEIQLRG PTIFKEYWRN EKATSEEFVP DPDGKGQWFK TGDVAIRRAV
QGSGKSSRTW ARGPMYFIQG RKSVDIIKTG GEKVSALEVE RELLSLPQIA EAAVVGLPSE
QWGQKVAAIL VLNPTSSLFS GANGGKKEKK FSALDMRRAL KDKLAPYKIP QEMRVLDGGL
PRNAMGKVNK KVLVKQVFGD KL
//
