ID A0A0J8UMJ0_COCIT Unreviewed; 361 AA.
AC A0A0J8UMJ0;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE RecName: Full=FAD-binding domain-containing protein {ECO:0000259|Pfam:PF01494};
GN ORFNames=CIHG_06426 {ECO:0000313|EMBL:KMU88758.1};
OS Coccidioides immitis H538.4.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=396776 {ECO:0000313|EMBL:KMU88758.1, ECO:0000313|Proteomes:UP000054563};
RN [1] {ECO:0000313|Proteomes:UP000054563}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H538.4 {ECO:0000313|Proteomes:UP000054563};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
CC -!- SIMILARITY: Belongs to the paxM FAD-dependent monooxygenase family.
CC {ECO:0000256|ARBA:ARBA00007992}.
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DR EMBL; DS017007; KMU88758.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0J8UMJ0; -.
DR STRING; 396776.A0A0J8UMJ0; -.
DR VEuPathDB; FungiDB:CIHG_06426; -.
DR eggNOG; KOG2614; Eukaryota.
DR Proteomes; UP000054563; Unassembled WGS sequence.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR002938; FAD-bd.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR PANTHER; PTHR13789; MONOOXYGENASE; 1.
DR PANTHER; PTHR13789:SF236; MONOOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G12060)-RELATED; 1.
DR Pfam; PF01494; FAD_binding_3; 1.
DR PRINTS; PR00420; RNGMNOXGNASE.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000054563}.
FT DOMAIN 36..257
FT /note="FAD-binding"
FT /evidence="ECO:0000259|Pfam:PF01494"
SQ SEQUENCE 361 AA; 39819 MW; 04C12AE204A49290 CRC64;
MNIFDYTGFD LGKHKLHGYN AGRGYTLNRG SLVFSMYDYA QKLGIKVFMG STVTEYWETE
DEAGIVVNGE KVAADCVICA EGIHSKGRAA ITGQEMQCKE TGFVSTRGYL EGKAAIQGPS
LTRIVSGMED GNCMYGWMGP RMHISMGIKI DGGELFWYAC HEAASVPPKN NSEAIDHILE
CMSDWTMRDE LESVVRNVSE GRFISQKLVV TTALKSWLSP RRRMIVIGDA AHAALPTSGQ
GGTQAIEDAA VLAIALELAG KQDIPLALSV TEKIRFKRAQ LIQQGGLAVL KFGMNRSDFE
LFRKDPNLAM PPHPAWIFDH DCQEYTYREF AAAAEAVRSG KDYVPTNIPA DGEYRMAYDS
K
//
