ID A0A0J9BK40_9GAMM Unreviewed; 183 AA.
AC A0A0J9BK40;
DT 14-OCT-2015, integrated into UniProtKB/TrEMBL.
DT 14-OCT-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Transcriptional regulator BetI {ECO:0000313|EMBL:KMV73414.1};
DE Flags: Fragment;
GN ORFNames=AI29_15300 {ECO:0000313|EMBL:KMV73414.1};
OS bacteria symbiont BFo2 of Frankliniella occidentalis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales.
OX NCBI_TaxID=1628856 {ECO:0000313|EMBL:KMV73414.1, ECO:0000313|Proteomes:UP000036794};
RN [1] {ECO:0000313|EMBL:KMV73414.1, ECO:0000313|Proteomes:UP000036794}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BFo2 {ECO:0000313|EMBL:KMV73414.1,
RC ECO:0000313|Proteomes:UP000036794};
RA Facey P.D., Hitchings M.D., Hegarty M.J., Pachebat J.A., Morgan L.V.,
RA Hoeppner J.E., Whitten M.A., Dyson P.J., Del Sol R.;
RT "The draft genomes, genome evolution and classification of BFo1 and BFo2
RT two insect symbionts isolated from Western Flower Thrips (Frankliniella
RT occidentalis [Pergande]).";
RL Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Repressor involved in the biosynthesis of the osmoprotectant
CC glycine betaine. It represses transcription of the choline transporter
CC BetT and the genes of BetAB involved in the synthesis of glycine
CC betaine. {ECO:0000256|ARBA:ARBA00024936}.
CC -!- PATHWAY: Amine and polyamine biosynthesis; betaine biosynthesis via
CC choline pathway [regulation]. {ECO:0000256|ARBA:ARBA00004719}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KMV73414.1}.
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DR EMBL; JMSP01000176; KMV73414.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0J9BK40; -.
DR STRING; 1628856.WB67_01880; -.
DR PATRIC; fig|1628856.3.peg.3077; -.
DR UniPathway; UPA00529; -.
DR Proteomes; UP000036794; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0019285; P:glycine betaine biosynthetic process from choline; IEA:UniProtKB-UniPathway.
DR Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR HAMAP; MF_00768; HTH_type_BetI; 1.
DR InterPro; IPR039538; BetI_C.
DR InterPro; IPR023772; DNA-bd_HTH_TetR-type_CS.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001647; HTH_TetR.
DR InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR InterPro; IPR017757; Tscrpt_rep_BetI.
DR NCBIfam; TIGR03384; betaine_BetI; 1.
DR PANTHER; PTHR30055:SF254; HTH-TYPE TRANSCRIPTIONAL REGULATOR BETI; 1.
DR PANTHER; PTHR30055; HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR; 1.
DR Pfam; PF13977; TetR_C_6; 1.
DR Pfam; PF00440; TetR_N; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF48498; Tetracyclin repressor-like, C-terminal domain; 1.
DR PROSITE; PS01081; HTH_TETR_1; 1.
DR PROSITE; PS50977; HTH_TETR_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00335};
KW Reference proteome {ECO:0000313|Proteomes:UP000036794};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 1..54
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DNA_BIND 17..36
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KMV73414.1"
SQ SEQUENCE 183 AA; 20075 MW; BFE64561D77E7133 CRC64;
IDATLATINE VGLHYATISQ IAKRAGVSTG IISHYFGDKN GLLEATMRDI TSKLQLAILE
RLKTLAGASA EERLSAIVDA NFDETQVHPA VAKAWLDFWA SSLHQPGLHR LQKISSRRLF
STLTAEFHKE LDKAPARVAG YGLAALIDGL WLRAALSGDP FDPQMIKTIT RQFIRQQLAS
THS
//
